Prof. Dr. Fathy Mohamed Abdel-Razek

Profile

Academic positionEmeritus
Research fieldsOrganic Molecular Chemistry
KeywordsHeterocyclic Synthesis

Current contact address

CountryEgypt
CityGiza
InstitutionCairo University
InstituteFaculty of Science, Department of Chemistry

Host during sponsorship

Prof. Dr. Hans Martin R. HoffmannInstitut für Organische Chemie, Gottfried Wilhelm Leibniz Universität Hannover, Hannover
Prof. Dr. Peter MetzInstitut für Organische Chemie, Technische Universität Dresden, Dresden
Start of initial sponsorship01/10/1987

Program(s)

1986Humboldt Research Fellowship Programme

Publications (partial selection)

2022Abdelrazek, F. M., A. M. S. Hebeishy, R. H. Ali: Synthesis and biological activity evaluation of some novel heterocyclic compounds incorporating pyridine / chromene moiety. In: Egypt. J. Chem., 65, 2022, 569-576
2021Fathy M. Abdelrazek, Sobhi M. Gomha, Mohamed S. Farghaly, Peter Metz: One-Pot, Three-Component Synthesis of Pyrido[2,3-d]pyrimidinones Using Aluminate Sulfonic Acid Nanocatalyst Under Grinding Technique. In: Polycyclic Aromatic Compounds, 41, 2021, 1472-1482
2021L. A. Al-Mutabagani, F. M. Abdelrazek, S. M. Gomha, A. S. Hebishy, M. S. Abdelfattah, S. M. Hassan, and M. M. Elaaser: Synthesis and biological evaluation of thiazolyl-ethylidene hydrazino-thiazole derivatives: A novel heterocyclic system.. In: Applied Sciences, 11, 2021, 8908-8920
2020Mansour, E., Ekhlas M. Nassar, Ahmed. F. El-Farargy, and F. M. Abdelrazek, An eco-friendly synthesis of some novel chromene-based heterocyclic compounds of biological interest.. In: Russ. J. BioOrg. Chem., 46, 2020, 582-589
2020Fathy M. Abdelrazek, Sobhi M. Gomha, Hassan M. Abdel-Aziz, Mohamed S. Farghaly, Peter Metz, Ahmed Abdel-Shafy Efficient Synthesis and In-Silico Study of Some Novel Pyrido[2,3-d][1,2,4]Triazolo[4,3-a]Pyrimidine Derivatives . In: J. Heterocyclic Chem., 2020, 1759-1769
2020 I. F. Nassar, A. F. El Farargy, F. M. Abdelrazek, Z. Hamza: Synthesis of new uracil derivatives and their sugar hydrazones with potent antimicrobial, antioxidant and anticancer activities.. In: Nucleosides, Nucleotides & Nucleic Acids, 2020, 991-1010
2019Abdelwahed R. Sayed, Sobhi M. Gomha, Fathy M. Abdelrazek, Mohamed S. Farghaly, Shaimaa A. Hassan, Peter Metz : Design, efficient synthesis and molecular docking of some novel thiazolyl-pyrazole derivatives as anticancer agents. In: BMC Chemistry, 2019, 1-13
2019Fathy M. Abdelrazek, Sobhi M. Gomha, Mohamed E. B. Shaaban, Kamal A. Rabee, Heba N. El-Shemy, Abanoub M. Abdallah, Peter Metz: One-Pot Three-Component Synthesis and Molecular Docking of Some Novel 2-Thiazolyl Pyridines as Potent Antimicrobial Agents. In: Mini-Reviews in Medicinal Chemistry, 2019, 527-538
2019Fathy M. Abdelrazek, Peter Metz, Anne Jaeger Some Reactions With Indane-1,3-dione: A Facile Synthesis of Pentacycline Heterocyclic Analogues. In: J. Heterocyclic Chem., 2019, 1939-1945
2018Fathy M. Abdelrazek, Sobhi M. Gomha, Mohamed E. B. Shaaban, Aziza I. Lotfi, Heba N. El-Shemy: Facile synthesis of some novel triazolo[3,4- b]thiadiazines and triazolo[4,3-b]tetrazines. In: Synthetic Communications, 2018, 32-37
2018Ibrahim F. Nassar, Ahmed F. El Farargy, Fathy M. Abdelrazek: Synthesis and Anti-Cancer Activity of Some New Fused Pyrazoles and Their Glycoside Derivatives. In: J. Heterocyclic Chem., 2018, 1709-1719
2018Sobhi M. Gomha, Fathy M. Abdelrazek, Aly H. Abdelrahman, Peter Metz: Synthesis of some new pyridine-based heterocyclic compounds with anticipated anti-tumor activity. In: J. Heterocyclic Chem., 2018, 1729-1737
2017Nadia H. Metwally, Fathy M. Abdelrazek, Salwa M. Eldaly, Peter Metz: 3-(3,5-Dimethyl-1H-Pyrazol-1-yl)-3-Oxopropanenitrile as Precursor for Some New Mono-Heterocyclic and Bis-Heterocyclic Compounds. In: J. Heterocyclic Chem., 2017, 289-294
2017Fathy M. Abdelrazek, Sobhi M. Gomha, Aly H. Abdelrahman, Peter Metz, Mohsen A. Sayed: A Facile Synthesis and Drug Design of Some New Heterocyclic Compounds Incorporating Pyridine Moiety and Their Antimicrobial Evaluation. In: Letters in Drug Design & Discovery , 2017, 752-762
2017Fathy M. Abdelrazek, Peter Metz, Anne Jäger, Nadia H. Metwally: An Eco-friendly Synthesis of Some Novel 4-methyl-4-hetaryl Chromene and Pyrano[2,3-c]pyrazole Derivatives. In: J. Heterocyclic Chem., 2017, 2313-2318
2017Ibrahim F. Nassar, Ahmed F. El Farargy, Fathy M. Abdelrazek, Nasser S.M. Ismail: Design, synthesis and anticancer evaluation of novel pyrazole, pyrazolo[3,4-d]pyrimidine and their glycoside derivatives. In: Nucleosides, Nucleotides & Nucleic Acids , 2017, 275-291
2017Fathy M. Abdelrazek, Sobhi M. Gomha, Peter Metz, Mohamed M. Abdalla: Synthesis of Some Novel 1,4-Phenylene-bis-thiazolyl Derivatives and Their Anti-hypertensive α-blocking Activity Screening. In: J. Heterocyclic Chem., 2017, 618-623
2016Sobhi M. Gomha, Fathy M. Abdelrazek: A Facile Three-Component One-Pot Synthesis of Some Novel Tricyclic Hetero-Ring Systems. In: J. Heterocyclic Chem., 2016, 1892-1896
2016Ekhlass M. Nassar, Fathy M. Abdelrazek, Rezk R. Ayyad, Ahmed F. El-Farargy: Synthesis and some reactions of 1-aryl-4-acetyl-5-methyl-1,2,3-triazoleDerivatives with anticonvulsant activity. In: Mini-Reviews in Medicinal Chemistry, 2016, 926-936
2016Sobhi M. Gomha, Fathy M. Abdelrazek, Aly H. Abdelrahman, Peter Metz: Synthesis of some novel thiazole, thiadiazole and 1,4-phenylene-bis-thiazole derivatives as potent anti-tumor agents.. In: Heterocycles (Jpn), 2016, 954-967
2015Fathy M. Abdelrazek, Maher H. Helal, Ali S. Hebishy, Safaa M. Hassan: A Novel Synthesis of Some 1,4-Phenylene-bis-heterocyclic Derivatives and of Some Pyran, Pyrano[2,3-c]pyrazole, and Pyrano[2,3-d]pyrimidine Derivatives. In: Journal of Heterocyclic Chemistry, 2015, 1026-1031
2015E. Nassar, A. F. El-Farargy, F. M. Abdelrazek: Synthesis of Some Novel Cyclooctane-Fused-Heterocycles with Anticipated Biological Activities. In: Journal of Heterocyclic Chemistry, 2015, 1395-1399
2015Fathy M. Abdelrazek, Mohamed S. Farghaly, Hussein E. Abdelrahman: Synthesis of Some Novel Heterocyclic Xylidinyl Amines and Carboxamides. In: J. Heterocyclic Chem. , 2015, 163-168
2015Sobhi M. Gomha, Fathy M. Abdelrazek, Mohamed M. Abdulla: Synthesis of new functionalised derivatives of [1,2,4]triazolo[4,3-a]pyrimidine and pyrimido[2,1-b][1,3,5]thiadiazine as aromatase inhibitors. In: Journal of Chemical Research, 2015, 425-429
2014Fathy Mohamed Abdel-Razek, Hamdi M. Hassaneen, Ekhlass M. Nassar, Anna Jager: Phenacyl Bromides Revisited: Facile Synthesis of Some New Pyrazoles, Pyridazines, and Their Fused Derivatives. In: J. Heterocyclic Chem., 2014, 475-481
2014Fathy M. Abdel-Razek, Nadia H. Metwally, Nazmi A. Kassab, Mohammed T. Jaafar, Peter Metz, Anne Jäger: Studies on the Reaction of Cycloalkanones with Malonodinitrile. In: J. Heterocyclic Chem., 2014, 1785-1790
2014Fathy M. Abdelrazek, Yehia M. Elkholy, Ali M. Salah, Nagwa M. Abdelazeem, Peter Metz: Synthesis of Some New Pyrazole, Pyrimidine, Pyridazine, and Their Fused Derivatives from 3-Oxo-3,N-diphenylpropionamide. In: J. Heterocyclic Chem., 2014, 824-829
2012Fathy M. Abdelrazek, Nehal A. Sobhy, Peter Metz, Akram A. Bazbouz: Synthetic Studies with 3-Oxo-N-[4-(3-oxo- 3-phenylpropionylamino)-phenyl]-3-phenylpropionamide. In: J. Heterocyclic Chem., 2012, 381-387
2011Fathy M. Abdelrazek, Ahmed A. Fadda, Samar S. Mohamed: Heterosynthesis Using Nitriles: Novel Pyrrolo[2,3-b]pyridines. In: International Journal of Organic Chemistry, 2011, 218-223
2011Fathy M. Abdelrazek, Ahmed A. Fadda, Akram N. Elsayed: Novel Synthesis of Some New Pyridazine and Pyridazino[4,5-d]pyridazine Derivatives. In: Synthetic Communications, 2011, 1119-1126
2011Ahmed Ali Fadda, Fathy Mohamed Abdelrazek, Ahmed Mahmoud Fouda: Studies with aza‐heterocyclic N‐oxides: Synthesis of some new aromatic N‐oxide derivatives.. In: European J. Chem., 2011, 51-57
2011Shams El-Din H. A.-Hafaz, Maisa I. A.-Monem, Mohamed G. Mohamed, Fathy M. Abdelrazek, Saoud A. M. Mettwally, Synthesis and reactions of some new selenolo[2,3-c]pyridazines . In: Chem. Heterocycl. Compounds, 2011, 441-449
2010Fathy M. Abdelrazek, Nadia H. Metwally, Nazmi A. Kassab, Nehal A. Sobhy Peter Metz, Anna Jaeger: SYNTHESIS OF SOME NOVEL POLYAZA FUSED HETEROCYCLIC COMPOUNDS.. In: J. Heterocyclic Chem., 2010, 384-388
2010Fathy Mohamed Abdelrazek, Nazmi Abdel‐Latif Kassab, Nadia Hanafy Metwally and Nehal Ahmed Sobhy: Synthesis of some novel pyridine and naphthyridine derivatives. In: Eur. J. Chem., 2010, 368-372
2010Ahmed Ali Fadda, Fathy Mohamed Abdelrazek, Khaled Samir Mohamed, Howayda Mohamed Mostafa Ghieth, Hassan Ali Etman: Synthetic applications of benzothiazole containing cyanoacetyl group. In: Eur. J. Chem., 2010, 90-95
2010Fathy Mohamed Abdel-Razek, Mohey F. Sharaf, Peter Metz, Anna Jaeger: The Reaction of 2-Dimethylaminomethylene-3-oxo-N-phenylbutyramide With Active Methylene Nitriles. In: J. Heterocyclic Chem., 2010, 528-533
2009Fathy Mohamed Abdel-Razek, Nadia H. Metwally, Nazmi A. Kassab, Nehal A. Sobhy: A novel synthesis of some 1,4-phenylene-bis-heterocyclic carboxamide derivatives. In: J. Heterocyclic Chem., 2009, 1380-1385
2009Fathy M. Abdel-Razek, Akram N. Elsayed: About the reaction of b-dimethylamino-a,b-enones with active methylene nitriles. In: J. Heterocyclic Chem., 2009, 949-953
2009Fathy M. Abdel-Razek, Nadia H. Metwally: Novel synthesis of N-arylpyrrole, pyrrolo[1,2-a]quinazoline, and pyrrolo[3,4-d]pyridazine derivatives. In: Synthetic Communications, 2009, 4088-4099
2008Tayseer A. Abdallah, Nadia H. Metwally, Fathy M. Abdelrazek: Heterocyclic Synthesis with ώ-bromoacetoplenone: Synthesis of Some New Pyrazole, Pyridazine and Furan derivatives. . In: Afinidad, 2008, 393-398
2008Fathy M. Abdelrazek, Nadia H. Metwally, Nehal A. Sobhy: Synthesis and Molluscicidal Activity of Some Newly Substituted Chromene and Pyrano[2,3-c]pyrazole Derivatives . In: Afinidad, 2008, 482-487
2008Fathy M. Abdelrazek, Ashraf M. Mohamed, Akram N. El Sayed: Synthesis of some new thieno[2,3-d]pyrimidine derivatives. In: Afinidad, 2008, 322-326
2007Fathy Mohamed Abdel-Razek, Said A. Ghozlan, Farid A. Michael: A Novel Synthesis of Some New Benzoyl-substituted Heterocycles from 2-Benzoyl-3-phenylpent-2-ene-1,5-dinitrile. In: J. Heterocyclic Chem., 2007, 63-67
2007Fathy M. Abdel-Razek, Peter Metz, Olga Kataeva, Anne Jäger, Sherif F. El-Mahrouky: Synthesis and Molluscicidal Activity of New Chromene and Pyrano [2,3-c]pyrazole Derivatives. In: Arch. Pharm. Chem. Life Sci. , 2007, 543-548
2007Fathy M. Abdel-Razek, Farid A. Michael, Sherif F. El-Mahrouky: Synthesis and molluscicidal activity of some new substituted-furan and furo [2,3-d]pyrimidine derivatives. In: International Journal of Physical Sciences, 2007, 212-216
2006Fathy Mohamed Abdel-Razek, Farid A. Michael: New Data About the Reaction of Benzyolacetonitrile with Malononitrile and Its Self-condensation. In: J. Heterocyclic Chem., 2006, 7-10
2006Fathy M. Abdelrazek, Peter Metz, Nadia H. Metwally, Sherif F. El-Mahrouky: Synthesis and molluscicidal activity of new cinnoline and pyrano[2,3-c]pyrazole derivatives. In: Arch. Pharm. Chem. life Sciences (Weinheim), 2006, 456-460
2006Fathy M. Abdelrazek, Farid A. Michael, A. E. Mohamed: Synthesis and molluscicidal activity of some 1,3,4-triaryl-5-chloropyrazole, pyrano[2,3- c]pyrazole, pyrazolylphthalazine and pyrano[2,3-d]thiazole derivatives. . In: Arch. Pharm. Chem. life Sciences (Weinheim) , 2006, 305-312
2006Fathy Mohamed Abdel-Razek, Farid A. Michael: Synthesis and some Reactions of 2-Benzoyl-3-phenylpent-2-ene-1,5-dinitrile. In: Afinidad, 2006, 335-338
2006Fathy Mohamed Abdel-Razek, Nadia H. Metwally: Synthesis of Some New N-Substituted Pyrroles, Pyrrolo[1,2-a]quinazoline, and Diaza-as-indacene Derivatives. In: Synthetic Communications, 2006, 83-89
2006Fathy Mohamed Abdel-Razek, Nadia H. Metwally, Nehal A. Sobhy: Synthesis of some New Pyridine and Pyrido-fused Derivatives From alpha-cyanomethylbenzylidene Malononitrile. In: Afinidad, 2006, 149-152
2005Fathy Mohamed Abdel-Razek, Alaa El-Din M. Fahty: A Novel Synthesis and Molluscicidal Activity of some functionally Substituted Pyridine, Pyrido-[3,2-c]pyridazine, and Pyrido[3,2-c]pyridazino-[2',3'-a]quinazoline Derivatives . In: Arch. Pharm. Chem. Life Sci., 2005, 329-334
2005Nadia H. Metwally, Fathy Mohamed Abdel-Razek, Nehal A. Sobhy: About the Reaction of alpha-Substituted Cinnamonitriles with 3-Substituted and 1,3 Disubstituted Pyrazolin-5-ones. In: Afinidad, 2005, 616-621
2005Fathy Mohamed Abdel-Razek: Heterocyclic Synthesis with Nitriles: Synthesis of Some New Thiophene, Pyridazine, Oxyzine, Thiopyran, Pyrrole, and Pyrrolo[1,2-b]pyridazine Derivatives. In: Synthetic Communications, 2005, 2251-2258
2005Nadia H. Metwally, Fathy Mohamed Abdel-Razek: Reaction of Anthranilonitrile with Some Active Methylene Reagents: Synthesis of Some New Quinoline and Quinazoline Derivatives. In: Synthetic Communications, 2005, 2481-2487
2004Fathy Mohamed Abdel-Razek, Peter Metz, Ebtehal K. Farrag: Synthesis and Molluscicidal Activity of 5-oxo-5,6,7,8-Tetrahydro-4H-Chromene Derivatives. In: Arch. Pharm. Pharm. Med. Chem. , 2004, 482-485
2004Fathy Mohamed Abdel-Razek, Nadia H. Metwally: The reaction of ethyl benzoylacetate with Ortho-substituted anilines. In: Afinidad, 2004, 134-138
2003Fathy M. Abdelrazek, Nadia H. Metwally: Some reactions with ώ-bromoacetophenone. A novel synthesis of some polysubstituted pyridine, pyrimidine, pyrazolo[1,5-a]pyrimidine and benzimidazolo[1,2-a]pyrimidine derivatives. . In: Afinidad , 2003, 554-557
1993Fathy M. Abdelrazek, Abdellatif M. Salah: Heterocyclic synthesis with nitriles: Synthesis of some new mercapto-substituted heterocycles from alkylidenemalononitrile . In: Bull. Chem. Soc. Jpn., 1993, 1722-1726
1992Fathy M. Abdelrazek, Abdellatif M. Salah, Zeinab. E. Elbazza: Synthesis of some novel thieno[2,3-d]pyrimidine, thieno[2,3-b]pyridine and thiazolo [3,2-a]thieno[2`,3`-d]pyrimidine derivatives and their effect on mycotoxins production. . In: Arch. Pharm. (Weinheim); , 1992, 301-305
1990Fathy M. Abdelrazek: Some reactions with ώ-bromoacetophenone: Synthesis of new pyrazole, pyrrole and furan derivatives. . In: J. Prakt. Chem., 1990, 479-483
1989Fathy M. Abdelrazek: Heterocyclic synthesis with nitriles: A novel synthesis of some thiophene and thieno[2,3-d]pyrimidine derivatives II . . In: Z. Naturforsch., 1989, 488-492
1989Fathy M. Abdelrazek: Heterocyclic synthesis with nitriles: Synthesis of some novel pyrazolo[1,5-a]pyrimidine and pyrrolo-[2`,3`:3,4]pyrazolo[1,5-a]pyrimidine derivatives. . In: J. Prakt. Chem., , 1989, 475-478
1988Fathy M. Abdelrazek, Hamed A. Ead: Heterocyclic synthesis with nitriles: A new approach to thiophene and thieno[2,3-d]pyrimidine derivatives. . In: J. Prakt. Chem. , 1988, 585-589
1988Fathy M. Abdelrazek, Ayman W. Erian, AbdelMoneim M. Torgoman: Some reactions with ώ-bromoacetophenone: Novel synthesis of polysubstituted pyrrole, furan, pyridine and pyridazine derivatives. . In: Chemistry & Industry (London), 1988, 30-32