Prof. Dr. Guangming Xiong

Profile

Academic positionFull Professor
Research fieldsGeneral Genetics, Functional Genome Research,Medicine
KeywordsGenetics, Microbiology, Molecular Biology, Biochemistry, Enzyme

Current contact address

CountryGermany
CityKiel
InstitutionUniversitätsklinikum Schleswig-Holstein
InstituteInstitut für Toxikologie und Pharmakologie für Naturwissenschaftler

Host during sponsorship

Prof. Dr. Walter DoerflerInstitut für Genetik, Universität zu Köln, Köln
Start of initial sponsorship01/03/1988

Program(s)

1987Humboldt Research Fellowship Programme

Publications (partial selection)

2001 Maser E, Xiong G, Grimm C, Ficner R, Reuter K: 3alpha-Hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni: biological significance tree-dimensional structure and gene regulation. In: Chem Biol Interact, 2001, 707-722
2001Xiong G, Martin H, Blum A, Schafer C, Maser E: A model on the regulation of 3alpha-hydroxysteroid dehydrogenese/carbonyl reductase expression in Comamonas testosteroni. In: Chem Biol Interact, 2001, 723-736
2001 Xiong G, Maser E: Regulation of the steroid-inducible 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase gene in Comamonas testosteroni. In: J Biol Chem, 2001, 9961-9970
2000Maser E, Mobus E, Xiong G: Functional expression, purificatiion, and characterization of 3 alpha-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni. In: Biochem Biophys Res Commun, 2000, 622-628
1998Xiong G, Lin J, Oepen P, Senerwa D, Lutz F: Control of effective expression of the phage phiCTX-encoded ctx gene in Pseudomonas aeruginosa by a promoter upstream of the cos site. In: Mol Gen Genet, 1998, 249-254
1996Xiong G, Lutz F Mutational analysis of bacteriophage phi CTX cos site. In: Virus Res., 1996, 149-156
1996Xiong G, Oepen P, Geiben R, el-Idrissi AH, Lutz F Plasmids containing cos ends inhibit the replication of phage phi CTX in Pseudomonas aeruginosa . In: Virus Res, 1996, 77-87
1995Struckmeier M, Xiong G, Lutz F: Pseudomonas aeruginosa cytotoxin: the Asp197-Gly-Asp-Tyr-His-Tyr-His-Tyt202 containing loop is critical for plasma membrane binding. In: Naunyn Schmiedebergs Arch Pharmcol, 1995, 315-319
1995Wang Z, Xiong G, Lutz F: Site-specific integration of the phage phi CTX genome into the Pseudomonas aeruginosa chromosome: characterization of the functional integrase gene located close to and upstreama of attP. In: Mol Gen Genet , 1995, 72-79
1994Xiong G, Struckmeier M, Lutz F Pore-forming Pseudomonas aeruginosa cytotoxin . In: Toxicology , 1994, 69-83
1993Elsabbagh H, Xiong G, Lutz F Nucleotide sequence of attP and cos sites of phage CTX and expression of cytotoxin in Pseudomonas aeruginosa PA158 5. Pore-forming Pseudomonas aeruginosa cytotoxin . In: Mol Gen Genet , 1993, 421-428
1992Xiong G, Lutz F: Site-directed mutagenesis of the Pseudomonas aeruginosa cytotoxin for probing toxic activity. In: Eur J Biochem. 1992;204(2):789-792 , 1992, 789-792