Nominator's project description
| Professor Michel Rohmer as a doctoral student detected the hopanoids as an important class of bacterial lipids. The bacterial hopanoids are by his finding considered as the precursors of the hopanoids and their
derivatives in crude oil and ancient sediments. His most important
contribution was the discovery of a new biosynthetic pathway for
isoprenoids in bacteria and plant chloroplasts. The pathway is also
occurring in plasmodia and therefore his discovery has opened an avenue for the development of antimalarial drugs. In the lab of Karl Poralla in Tuebingen bacterial genes for the biosynthesis of hopanoids will be isolated and characterized. |
Publications (partial selection)
| 2001 | Michel Rohmer, Jean-Michel Bravo, Michael Perzl, Thomal Härtner, Elmar L. Kannenberg: Novel methylated triterpenoids of the gammacerane series from the nitrogen-fixing bacterium Bradyrhizobium japonicum USDA 110. In: Eur. J. Biochem., 2001, 1323-1331 |
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