Prof. Dr. Hirobumi Yamamoto

Profile

Academic positionFull Professor
Research fieldsPharmacy,Plant Biochemistry and Biophysics
KeywordsLithospermum erythrorhizon, plant cell cultures, shikonin production, enzymes, biosynthesis

Current contact address

CountryJapan
CityGunma
InstitutionToyo University
InstituteFaculty of Sciences

Host during sponsorship

Prof. Dr. Lutz HeideAbteilung Pharmazeutische Biologie, Eberhard Karls Universität Tübingen, Tübingen
Start of initial sponsorship01/08/1998

Programme(s)

1997Humboldt Research Fellowship Programme

Publications (partial selection)

2008Kanako Sasaki, Kouji Mito, Kazuaki Ohara, Hirobumi Yamamoto, Kazufumi Yazaki: Cloning and Characterization of Naringenin 8-Prenyltransferase, a Flavonoid-Specific Prenyltransferase of Sophora flavescens. In: Plant Physiology, 2008, 1075-1084
2007Nobuyoshi Sato, Minoru Uehara, Koichiro Shimomura, Hirobumi Yamamoto, Kenichi Kamijo: Outlier Rejection in Massive Trace Element Data for Geographical Origin Identification System of Vegetables. In: Journal of Networks, 2007, 61-68
2006Nobuyoshi Sato, Minoru Uehara, Koichiro Shimomura, Hirobumi Yamamoto, Kenichi Kamijo: Efficient Retrieval on Dense Vector by Similarity Preserve Hash in Vegetable Geographical Origin Identification System. In: International Journal of Computer Science and Network Security, 2006, 227-235
2006Rahnab L.-ur, Kitamura Y., Yamaguchi J., Murai M., Akiyama K., Yamamoto H., Muranaka T., Ikenaga T.: Exogenous plant H6H but not bacterial HCHL gene is expressed in Duboisia leichhardtii hairy roots and affect tropane alkaloid production. In: Emzyme and Microbial Technology, 2006, 1183-1189
2005Sato N., Uehara M., Tamaoka J., Shimomura K., Yamamoto H., Kamijo K.: A Distributed Geographical Origin Identification System for Agricultural Products by Trace Element Compositions. In: International J. Computer Science and Network Security, 2005, 55-63
2005Taguchi G., Shitchi Y., Shirasawa S., Yamamoto H., Hayashida N.: Molecular cloning, characterization, and downregulation of an acyltransferase that catalyzes the malonylation of flavonoid and naphthol glucosides in tobacco cells. In: The Plant Journal, 2005, 481-491
2004Ohara K., Kokado Y., Yamamoto H., Sato F., Yazaki K: Engineering of ubiquinone biosynthesis using the yeast coq2 gene confers oxidative stress tolerance in transgenic tobacco. In: The Plant Journal, 2004, 734-743
2004Yamamoto H., Kuribayashi H., Seshima Y., Zhao P., Kouno I., Taguchi G., Shimomura K.: Metabolism of administered (2RS)-naringenin in flavonoid-producing cultured cells of Sophora flavescens. In: Plant Biotechnology, 2004, 355-359
2004Zhao P., Zhang Y.-G., Yamamoto H., Yang C.-G.: Recent advance on the chemistry, bioactivity and biosynthesis of prenylated flavonoids from Sophora flacescens. In: Tianran Chanwu Yanjiu Yu Kaifa, 2004, 172-178
2004P. Zhao, Y. Iwamoto, I. Kouno, Y. Egami, H. Yamamoto: Stimulating the production of homoisoflavonoids in cell suspension cultures of Caesalpinia pulcherrima using cork tissue. In: Phytochemistry , 2004, 2455-2461
2003P. Zhao, K. Inoue, I. Kouno, H. Yamamoto: Characterization of leachianone G 2'' -dimethylallyltransferase, a novel prenyl side-chain elongation enzyme for the formation of the lavandulyl group of sophoraflavanone G in Sophora flavescens Ait. cell suspension cultures. In: Plant Physiology, 2003, 1306-1313
2003G. Taguchi, T. Ubukata, N. Hayashida, H. Yamamoto, M. Okazaki: Cloning and characterization of a glucosyltransferase that reacts on 7-hydroxyl group of flavonol and 3-hydroxyl group of coumarin from tobacco cells. In: Arch. Biochem. Biophys., 2003, 95-102
2003P. Zhao, C. Hamada, K. Inoue, H. Yamamoto: Efficient production and capture of 8-prenylnaringenin and leachianone G ¿ biosynthetic intermediates of sophoraflavanone G ¿ by the addition of cork tissue to cell suspension cultures of Sophora flavescens. In: Phytochemistry, 2003, 1093-1099
2003H. Yamamoto, M. Hori, H. Kuwajima, K. Inoue: Formation of benzoquinol moiety in cornoside by salidroside mono-oxygenase, a cytochrome P450 enzyme, from Abeliophyllum distichum cell suspension cultures. In: Planta, 2003, 432-436
2003K. Terasaka, K. Sakai, F. Sato, H. Yamamoto, K. Yazaki: Thalictrum minus cell cultures and ABC-like transporter. In: Phytochemistry, 2003, 483-489
2002H. Yamamoto, M. Sha, Y. Kitamura, M. Yamaguchi, N. Katano, K. Inoue: Iridoid biosynthesis: 7-deoxyloganetic acid 1-O-glucosyltransferase in cultured Lonicera japonica cells. In: Plant Biotechnology, 2002, 295-301
2002H. Yamamoto, P. Zhao, K. Inoue: Origin of two isoprenoid units in a lavandulyl moiety of sophoraflavanone G from Sophora flavescens cultured cells. In: Phytochemistry, 2002, 263-267
2002H. Yamamoto, P. Zhao, K. Yazaki, K. Inoue: Regulation of lithospermic acid B and shikonin production in Lithospermum erythrorhizon cell suspension cultures. In: Chemical & Pharmaceutical Bulletin, 2002, 1086-1090
2001H. Yamamoto, A. Yatou, K. Yazaki, H. Hayashi, G. Taguchi, K. Inoue: Increases of secondary metabolite production in various plant cell cultures by co-cultivation with cork. In: Bioscience, Biotechnology and Biochemistry, 2001, 853-860
2001N. Katano, H. Yamamoto, R. Iio, K. Inoue: 7-Deoxyloganin 7-hydroxylase in Lonicera japonica cell cultures. . In: Phytochemistry, 2001, 53-58
2001H. Yamamoto, A. Yatou, K. Inoue: 8-Dimethylallylnaringenin 2¿-hydroxylase, the crucial cytochrome P450 monooxygenase for lavandulylated flavanone formation in Sophora flavescens cultured cells. In: Phytochemistry, 2001, 671-676
2001H. Yamamoto, A. Yatou, K. Yazaki, H. Hayashi, G. Taguchi, K. Inoue: Increases of secondary metabolite production in various plant cell cultures by co-cultivation with cork. In: Bioscience, Biotechnology and Biochemistry, 2001, 853-860
2001A.B. Kirakosyan, R.R. Vardapetyan, A.G. Charchoglyan, H. Yamamoto, H. Hayashi, K. Inoue: The effect of cork pieces on pseudohypericin production in cells of Hypericum perforantum shoots. In: Russian Journal of Plant Physiology, 2001, 816-819
2000H. Yamamoto, M. Senda, K. Inoue: Flavanone 8-dimethylallyltransferase in Sophora flavescens cell suspension cultures. In: Phytochemistry, 2000, 649-655
2000H. Yamamoto, K. Inoue, S.-M. Li, L. Heide: Geranylhydroquinone 3¿-hydroxylase, a cytochrome P-450 monooxygenase from Lithospermum erythrorhizon cell suspension cultures. In: Planta, 2000, 312-317
2000H. Hayashi, N. Hosono, M. Kondo, N. Hiraoka, Y. Ikeshiro, M. Shibano, G. Kusano, H. Yamamoto, T. Tanaka K. Inoue: Phylogenetic relationship of six Glycyrrhiza species based on rbcL sequences and chemical constituents. In: Biological & Pharmaceutical Bulletin, 2000, 602-606
2000H. Yamamoto, K. Yazaki, K. Inoue: Production of caffeic acid oligomers in Lithospermum erythrorhizon cell suspension cultures. In: Phytochemistry, 2000, 651-657
2000H. Yamamoto, N. Katano, A. Ooi, K. Inoue: Secologanin synthase which catalyzes the oxidative cleavage of loganin into secologanin is a cytochrome P-450. In: Phytochemistry, 2000, 7-12
2000H. Yamamoto, K. Yazaki, K. Inoue: Simultaneous analysis of shikimate-derived secondary metabolites in Lithospermum erythrorhizon cell suspension cultures by high-performance liquid chromatography. In: Journal of Chromatography B: Biomedical Sciences and Applications, 2000, 3-15