Prof. Dr. Antti Poso

Profile

Academic positionFull Professor
Research fieldsPharmacy,Theoretical Chemistry: Electron Structure, Dynamics, Simulation
KeywordsCannabinoids, Drug Design, Molecular modelling, QSAR, Drug-receptor interaction

Current contact address

CountryGermany
CityTübingen
InstitutionEberhard Karls Universität Tübingen
InstituteArbeitskreis Pharmazeutische Biochemie

Host during sponsorship

Prof. Dr. Hans-Dieter HöltjeInstitut für Pharmazeutische und Medizinische Chemie, Heinrich-Heine-Universität Düsseldorf, Düsseldorf
Prof. Dr. Markus KalesseInstitut für Organische Chemie, Gottfried Wilhelm Leibniz Universität Hannover, Hannover
Start of initial sponsorship01/01/1998

Programme(s)

1997Humboldt Research Fellowship Programme

Publications (partial selection)

2002J. Päivärinta, Antti T. Poso, M. Hotokka, E. Muttonen: Molecular Dynamics of Steroid Structures in Different Solvents. In: Chrystal growth & Design, 2002, 121-126
2002J.I. Venäläinen, R.O. Juvonen, M.M. Forsberg, A. Garcia-Horsman, Antti T. Poso, E.A. A. Wallen, J. Gynther, P.T. Männistö: Substrate-Dependent, Nonhyperbolic Kinetics of Pig Brain Prolyl Oligopeptidase and its Tight Binding Inhibition by JTP-4819. In: Biochem Pharmacol, 2002, 463-471
2001A. Poso, J. Gynther, R. Juvonen: A Comperative Molecular Field Analysis of cytochrome P450 2A5 and 2A6 inhibitors. In: J. Comp-Aid. Mol. Des., 2001, 195-202
2001J. Päivärinta, S. Karlsson, A. Poso, M. Hotokka: Calculated molecular properties for different alkanoic acid-alkylamine complexes: A comparison with measured FTIR and Raman spectra. In: Chemical Physics, 2001, 127-138
2001S. Karlsson, J. Päivärinta, R. Friman, Antti T. Poso, M. Hotokka, S. Backlund: Characterization of the Phase Behaviour and Complexation in the Heptanoic Acid-Heptylamine-Water System. In: J. Phys. Chem, 2001, 7944-7949
2001M. Tarvainen, R. Sutinen, M. Kinnunen, P. Paronen, Antti T. Poso: Predicting Plasticization Efficiency from Three-Dimensional Molecular Structure of the Polymer Plasticizer. In: Pharm. Res., 2001, 1760-1766
2000JT. Kovalainen, JA Christiaans, R. Ropponen, A. Poso, M. Peräkylä, J.Vepsäläinen, R. Laatikainen, J. Gynther: A proton relay process as the mechanism of activations of the histamine H3-receptor determined by 1H-NMR and ab initio quantum mechanical calculations. In: Journal of the American Chemical Society, 2000, 6989-6996
2000J. Päivärinta, S. Karlsson, M. Hotokka, A. Poso: Calculated and measured vibrational frequencies in an alkanoic adic-alkylamine complex. In: Chem. Phys. Lett., 2000, 420-424
2000E. Suihko, A. Poso, O. Korhonen, J. Gynther, J. Ketolainen, P. Paronen Deformation behaviour of tolbutamide, hydroxyprpyl-ß-cyclodextrin and their physical and molecular dispersions. In: Pharm Res., 2000, 942-948
2000Antti T. Poso, R. Juvonen, G. Gynther, M. Pasanen, E. Alhava: Pronounced differences in inhibition potency of lactone and non-lactone compounds between mouse and human coumarin 7-hydroxylases (CYP2A5 and CYP2A6). In: Xenobiotica, 2000, 81-92
1999J. Kovalainen, J. Christiaans, Antti T. Poso, J. Vepsäläinen, R. Laatikainen, J. Gynther: 1H NMR study of putative intramolecular hydrogen bonding for histamine H3-receptor agonists . In: Tetrahedron Lett., 1999, 2425-2428
1999A. Bauer-Brandl, M. E. Geoffroy, Antti T. Poso, J. Suurkuusk, E. Wappler, K. H. Bauer: Comparison of experimental methods and theoretical calculations on crystal energies of 'isoenergetic' polymorphs of cimetidine . In: J. Therm. Anal. Calor., 1999, 7-22