Dr. Ajay Khopade

Profile

Academic positionCurrently without academic position
Research fieldsPharmacy,Basic Research in Biology and Medicine
KeywordsDrug delivery, ultrathin capsules, Novel drug delivery systems, Self-assembly, Nanotechnology
Honours and awards

2022: Express Pharma, FDD leadership award, Jurys choice

2022: India Pharma Awards, Excellence in R&D, Special recognition

2002: JSPS fellowship, Japan

Current contact address

CountryIndia
CityVadodara
InstitutionSun Pharma Advanced Research Company Limited
InstituteDepartment of Formulation Development

Host during sponsorship

Prof. Dr. Frank CarusoAbteilung Grenzflächen, Max-Planck-Institut für Kolloid- und Grenzflächenforschung, Golm
Start of initial sponsorship01/03/2001

Programme(s)

2000Humboldt Research Fellowship Programme

Publications (partial selection)

2025Ramachandran, Gayathri and Chacko, Indhu Annie and Mishara, MG and Khopade, Ajay Jaysingh and Sabitha, M and Sudheesh, MS: A review on design rules for formulating amorphous solid dispersions based on drug-polymer interactions in aqueous environment. In: International journal of pharmaceutics, 675, 2025, 125541
2023Khopade, Ajay J and Halder, Arindam and Patel, Vivek and Shah, Harsh and Shah, Ankit and Burade, Vinod and Zalawadia, Rishit and Patel, Alpesh: Low dose ophthalmic solution of difluprednate for the management of pain and inflammation. In: Journal of Drug Delivery Science and Technology, 83, 2023, 104387
2022Halder, Arindam and Shah, Malay D and Pateliya, Bharat and Burade, Vinod and Khopade, Ajay J: A gel-free reservoir system for once-a-day ophthalmic delivery of Timolol maleate. In: Journal of Pharmaceutical Innovation, 17, 2022, 1247--1258
2022Ghosh, Saikat and Mishra, Pooja and Banerjee, Shubhadeep and Maiti, Kuntal and Khopade, Ajay and Misra, Ambikanandan and Sawant, Krutika and Bhowmick, Subhas: Exploration of the cardinal formulation parameters influencing the encapsulation and physicochemical properties of co-loaded anticancer dual drug nanoliposomes. In: Journal of Drug Delivery Science and Technology, 71, 2022, 103295
2022Khopade, Ajay J and Halder, Arindam and Burade, Vinod and Pateliya, Bharat and Jani, Kaushal and Patel, Vivek and Upadhyay, Shivam: Ophthalmic suspension of Brimonidine for sustained delivery using nano-resin/drug complex technique. In: Journal of Drug Delivery Science and Technology, 75, 2022, 103594
2021Ma, Wen Wee and Zhu, Mojun and Lam, Elaine T and Diamond, Jennifer R and Dy, Grace K and Fisher, George A and Goff, Laura Williams and Alberts, Steven and Bui, Lynne A and Sanghal, Akhil and others: A phase I pharmacokinetic and safety study of Paclitaxel Injection Concentrate for Nano-dispersion (PICN) alone and in combination with carboplatin in patients with advanced solid malignancies and biliary tract cancers. In: Cancer chemotherapy and pharmacology, 87, 2021, 779--788
2021Halder, Arindam and Khopade, Ajay J: Pharmacokinetics and pharmacology of latanoprost 0.005% without benzalkonium chloride vs latanoprost 0.005% with benzalkonium chloride in New Zealand white rabbits and beagles. In: Current Eye Research, 46, 2021, 1031--1037
2021Ghosh, Saikat and Javia, Ankit and Shetty, Saritha and Bardoliwala, Denish and Maiti, Kuntal and Banerjee, Shubhadeep and Khopade, Ajay and Misra, Ambikanandan and Sawant, Krutika and Bhowmick, Subhas: Triple negative breast cancer and non-small cell lung cancer: Clinical challenges and nano-formulation approaches. In: Journal of Controlled Release, 337, 2021, 27--58
2020Tripathi, Pushpendra Kumar and Gupta, Shraddha and Rai, Suruchi and Shrivatava, Ankur and Tripathi, Shalini and Singh, Sima and Khopade, Ajay J and Kesharwani, Prashant: Curcumin loaded poly (amidoamine) dendrimer-plamitic acid core-shell nanoparticles as anti-stress therapeutics. In: Drug development and industrial pharmacy, 46, 2020, 412--426
2020Halder, Arindam and Khopade, Ajay J: Physiochemical properties and cytotoxicity of a benzalkonium chloride-free, micellar emulsion ophthalmic formulation of latanoprost. In: Clinical Ophthalmology, 2020, 3057--3064
2017Khopade, Ajay and Halder, Arindam and Shah, Malay and Burade, Vinod and Ruan, Harry and Desai, Dipali and others: A novel BAK free, room temperature stable, swollen micelle microemulsion formulation of latanoprost. In: Investigative Ophthalmology \& Visual Science, 58, 2017, 4117--4117
2016Jain, Minish M and Gupte, Smita U and Patil, Shekhar G and Pathak, Anand B and Deshmukh, Chetan D and Bhatt, Niraj and Haritha, Chiramana and Govind Babu, K and Bondarde, Shailesh A and Digumarti, Raghunadharao and others: Paclitaxel injection concentrate for nanodispersion versus nab-paclitaxel in women with metastatic breast cancer: a multicenter, randomized, comparative phase II/III study. In: Breast cancer research and treatment, 156, 2016, 125--134
2008Omray, LK and Kohli, S and Khopade, AJ and Patil, S and Gajbhiye, Asmita and Agrawal, GP: Development of mesophasic microreservoir-based transdermal drug delivery system of propranolol. In: Indian journal of pharmaceutical sciences, 70, 2008, 578
2007Upadhyay, Kamal K and Tiwari, Chandraprabha and Khopade, Ajay J and Bohidar, Himadri B and Jain, Sanjay K: Sorbitan ester organogels for transdermal delivery of sumatriptan. In: Drug development and industrial pharmacy, 33, 2007, 617--625
2005Khopade, Ajay J and Arulsudar, N and Khopade, Surekha A and Knocke, Roy and Hartmann, Jürgen and Möhwald, Helmuth: From ultrathin capsules to biaqueous vesicles. In: Biomacromolecules, 6, 2005, 3433--3439
2005Khopade, Ajay J and Möhwald, Helmuth: Pseudobilayer Vesicle Formation via Layer-by-Layer Assembly of Hydrophobically Modified Polymers on Sacrificial Substrates. In: Advanced Functional Materials, 15, 2005, 1088--1094
2005Khopade, Ajay J and Möhwald, Helmuth: Statistical megamer morphologies and materials from PAMAM dendrimers. In: Macromolecular rapid communications, 26, 2005, 445--449
2004A. J. Khopade and F. Caruso: Two-Component, Ultrathin Microcapsules Prepared by a Core-Mediated Layer-by-Layer Approach 4. Khopade AJ, Caruso F Surface-modification of polyelectrolyte multilayer-coated particles for biological applications Langmuir 2003 19, 6219. . In: Chem. Mater. , 2004, 2107 -2112
2004Ajay Khopade, F. Caruso: Core-assisted multilayer growth of polyelectrolyte films. In: Chem. Mater., 2004, 2107-2112
2004Khopade, Ajay J and Shenoy, Dinesh B and Khopade, Surekha A and Jain, Narendra K: Phase structures of a hydrated anionic phospholipid composition containing cationic dendrimers and pegylated lipids. In: Langmuir, 20, 2004, 7368--7373
2004Chauhan, Abhay Singh and Jain, Narendra Kumar and Diwan, Prakash Vamanrao and Khopade, Ajay Jaysingh: Solubility enhancement of indomethacin with poly (amidoamine) dendrimers and targeting to inflammatory regions of arthritic rats. In: Journal of drug targeting, 12, 2004, 575--583
2004Khopade, Ajay J and Caruso, Frank: Two-component, ultrathin microcapsules prepared by a core-mediated layer-by-layer approach. In: Chemistry of materials, 16, 2004, 2107--2112
2003PK. Tripathi, Ajay Khopade, T. Dutta, et al.: Dendrimer Polycation for Delivery of Genes. In: Ind. J. Pharm. Sci., 2003,
2003Tripathi, PK and Khopade, AJ and Dutta, T and Umamaheshewari, RB and Jain, S and Saraf, DK and Jain, NK: Dendrimer polycation for delivery of genes. In: Indian journal of pharmaceutical sciences, 65, 2003, 15--21
2003Ajay Khopade, F. Caruso: Suface-modification of polyelectrolyte multilayer-coated particles for biological applications. In: Langmuir, 2003, 6219
2003Khopade, Ajay J and Caruso, Frank: Surface-modification of polyelectrolyte multilayer-coated particles for biological applications. In: Langmuir, 19, 2003, 6219--6225
2002Ajay Khopade: Delivering with dendrimers. In: Nature material update (net edition), 2002,
2002Tripathi, PK and Khopade, AJ and Nagaich, S and Shrivastava, S and Jain, S and Jain, NK: Dendrimer grafts for delivery of 5-fluorouracil.. In: Die Pharmazie, 57, 2002, 261--264
2002P. Tripathi, Ajay Khopade, S. Nagaich et al.: Dendrimer grafts for delivery of 5-flurouracil. In: Pharmazie, 2002, 261-264
2002Khopade, AJ and Khopade, Surekha and Jain, NK: Development of hemoglobin aquasomes from spherical hydroxyapatite cores precipitated in the presence of half-generation poly (amidoamine) dendrimer. In: International journal of pharmaceutics, 241, 2002, 145--154
2002Khopade AJ. Khopade S. Jain NK: Development of hemoglobin aquasomes from spherical hydroxyapatite cores precipitated in the presence of half-generation poly(amidoamine) dendrimer.. In: International Journal of Pharmaceutics, 2002, 145-154
2002Khopade, Ajay J and Caruso, Frank and Tripathi, Pushpendra and Nagaich, Surekha and Jain, Narendra K: Effect of dendrimer on entrapment and release of bioactive from liposomes. In: International journal of pharmaceutics, 232, 2002, 157--162
2002Khopade AJ. Caruso F. Tripathi P. Nagaich S. Jain NK.: Effect of dendrimer on entrapment and release of bioactive from liposomes.. In: International Journal of Pharmaceutics, 2002, 157-162
2002A.J. Khopade, F. caruso: Electrostatically Assembled Polyelectrolyte/Dendrimer Multilayer Films as Ultrathin Nanoreservoirs. In: Nano Letters, 2002, 415-418
2002Khopade, Ajay J and Caruso, Frank: Electrostatically assembled polyelectrolyte/dendrimer multilayer films as ultrathin nanoreservoirs. In: Nano Letters, 2, 2002, 415--418
2002Ajay J. Khopade and Frank Caruso: Investigation of the Factors Influencing the Formation of Dendrimer/Polyanion Multilayer Films. In: Langmuir , 2002, 7669-7676
2002Khopade, Ajay J and Caruso, Frank: Investigation of the factors influencing the formation of dendrimer/polyanion multilayer films. In: Langmuir, 18, 2002, 7669--7676
2002Ajay J. Khopade and Frank Caruso: Stepwise Self-Assembled Poly(amidoamine) Dendrimer and Poly(styrenesulfonate) Microcapsules as Sustained Delivery Vehicles. In: Biomacromolecules, 2002, 1154-1162
2002Khopade, Ajay J and Caruso, Frank: Stepwise self-assembled poly (amidoamine) dendrimer and poly (styrenesulfonate) microcapsules as sustained delivery vehicles. In: Biomacromolecules, 3, 2002, 1154--1162
2000Khopade, AJ and Jain, NK: Biovectors for Tumour Therapy: Lipoprotein Mimicking Biovectorized Systems. In: INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 62, 2000, 168--174
2000S. Nagaich, Ajay Khopade, NK Jain: Biovectors for tumour therapy: Lipoprotein mimicking biovectorized systems. In: Ind. J. Pharm. Sci., 2000,
2000Ajay Khopade, NK Jain: Concanavalin-A conjugated fine-multiple emulsion loaded with 6-mercaptopurine. In: Drug Delivery, 2000, 105-112
2000Khopade, AJ and Jain, NK: Concanavalin-A conjugated fine-multiple emulsion loaded with 6-mercaptopurine. In: Drug delivery, 7, 2000, 105--112
2000D. Taneja,A. Namdeo, PR Mishra, Ajay Khopade et al.: High-entrapment liposomes for 6-Mercaptopurine - A prodrug approach. In: Drug Dev. Ind. Pharm, 2000, 1315-1319
2000Taneja, Dinesh and Namdeo, Alok and Mishra, PR and Khopade, AJ and Jain, NK: High-entrapment liposomes for 6-mercaptopurine—a prodrug approach. In: Drug development and industrial pharmacy, 26, 2000, 1315--1319
2000Ajay Khopade, U. Shelly, NK Pandit et al.: Liposphere based lipoprotein-mimetic delivery system for 6-mercaptopurine. In: J. Biomater. Appl., 2000, 389-398
2000Khopade, AJ and Shelly, C and K. Pandit, N and Banakar, UV: Liposphere based lipoprotein-mimetic delivery system for 6-mercaptopurine. In: Journal of biomaterials applications, 14, 2000, 389--398
2000Golikere, CS and Patil, UK and Khopade, AJ and Mahadik, KR: Studies on Artemisia pallens Wall (Davana) from Jejuri Region of Maharashtra (India). In: INDIAN DRUGS-BOMBAY-, 37, 2000, 396--398
1999Patil, S and Khopade, AJ and Nagaich, S and Agrawal, GP and Jain, NK: Adsorption studies of sugars on calcium hydroxy apatite ceramics and haemoglobin on sugar coated ceramics. In: Pharmazie, 54, 1999, 310--312
1999Khopade, AJ and Jain, NK: Fine multiple emulsions bearing 6-mercaptopurine: In Vitro and In Vivo antitumor studies. In: Drug Delivery, 6, 1999, 181--185
1999Namdeo, Alok and Mishra, PR and Khopade, AJ and Jain, NK: Formulation and evaluation of niosome encapsulated indomethacin. In: Indian Drugs, 36, 1999, 378--380
1999Nagaich, Surekha and Khopade, AJ and Jain, NK: Lipid grafts of egg-box complex: a new supramolecular biovector for 5-fluorouracil delivery. In: Pharmaceutica Acta Helvetiae, 73, 1999, 227--236
1999Utreja, Shelly and Khopade, AJ and Jain, NK: Lipoprotein-mimicking biovectorized systems for methotrexate delivery. In: Pharmaceutica Acta Helvetiae, 73, 1999, 275--279
1999Khopade, AJ and Jain, NK: Long-circulating multiple-emulsion system for improved delivery of an anticancer agent. In: Drug Delivery, 6, 1999, 107--110
1999Khopade, AJ and Jain, NK: Multiple emulsions containing rifampicin.. In: Die Pharmazie, 54, 1999, 915--919
1998Khopade, AJ and Jain, NK: A stable multiple emulsion system bearing isoniazid: preparation and characterization. In: Drug development and industrial pharmacy, 24, 1998, 289--293
1998Khopade, AJ and Jain, NK: Effects of drug concentration in inner aqueous phase and additives in oleaginous phase on release and bioavailability of isoniazid from multiple emulsion. In: Drug development and industrial pharmacy, 24, 1998, 677--680
1998Sant, VP and Khopade, AJ and Jain, NK: Iontophoretic transdermal delivery of salbutamol: methyl-orange ion-pair.. In: Die Pharmazie, 53, 1998, 334--336
1998Khopade, AJ and Nandakumar, KS and Jainb, NK: Lectin-functionalized multiple emulsions for improved cancer therapy. In: Journal of drug targeting, 6, 1998, 285--292
1998Vora, Bhavana and Khopade, Ajay J and Jain, NK: Proniosome based transdermal delivery of levonorgestrel for effective contraception. In: Journal of controlled release, 54, 1998, 149--165
1997Deo, MR and Khopade, AJ and Jain, NK: DEVELOPMENT OF LIQUID CRYSTALLINE PROLIPOSOMAL GEL FOR SUSTAINED OPHTHALMIC DRUG DELIVERY. In: Indian drugs, 34, 1997, 252--257
1997Gandhi, R and Khopade, AJ and Jain, NK: DIFFERENCE SPECTROPHOTOMETRIC METHOD FOR DETERMINATION OF METHOTREXATE IN TABLETS. In: Indian drugs, 34, 1997, 455--458
1997Mishra, PR and Jain, S and Khopade, AJ and Jain, NK: Difference Spectrophotometric Determination of Doxorubicin Hydrochloride in Injection. In: Indian drugs, 34, 1997, 602--603
1997Khopade, AJ and Gandhi, R and Jain, NK: Difference Spectrophotometric Estimation of 5-Fluorouracil. In: Eastern pharmacist, 40, 1997, 125--126
1997Khopade, AJ and Jain, NK: Long-circulating lipospheres targeted to the inflammed tissue.. In: Die Pharmazie, 52, 1997, 165--166
1997Deo, MR and Sant, VP and Parekh, SR and Khopade, AJ and Banakar, UV: Proliposome-based transdermal delivery of levonorgestrel. In: Journal of biomaterials applications, 12, 1997, 77--88
1997Taneja, LN and Khopade, AJ and Jain, NK: Solid Dispersions of Ketoprofen: In-Vitro Characterization and Bioavailability Assessment. In: Indian drugs, 34, 1997, 72--77
1997Khopade, AJ and Jain, NK: Stabilized multiple emulsions with uni/oligo-droplet internal phase. In: Pharmazie, 52, 1997, 562--564
1997Uppadhyay, AK and Omray, LK and Khopade, AJ and Jain, NK: Studies on a reverse micelle-lamellar phase transition based depot preparation of rifampicin.. In: Die Pharmazie, 52, 1997, 961--962
1996Khopade, AJ and Mahadik, KR and Jain, NK: Enhanced brain uptake of rifampicin from w/o/w multiple emulsions via nasal route. In: Indian journal of pharmaceutical sciences, 58, 1996, 83--85
1996Sant, VP and Deo, MR and Khopade, AJ and Parakh, SR and Deshpande, SG: Iontophoretically facilitated transdermal delivery of salbutamol sulphate. In: Indian drugs, 33, 1996, 202--207
1996Khopade, AJ and Mahadik, KR and Jain, NK: Targeting of multiple emulsions to the lungs.. In: Die Pharmazie, 51, 1996, 558--562
1995Khopade, AJ and Jain, NK: Self assembling nanostructures for sustained ophthalmic drug delivery.. In: Die Pharmazie, 50, 1995, 812--814
n.n.khopade: Polymeric micelles in colon targeting. . n.n..
n.n.: Recent Advancement in Capsule: Emerging Novel Technologies and Alternative Shell Materials for Wide Range of Therapeutic Needs. n.n.,
Ajay J. Khopade and Frank Caruso: Surface-Modification of Polyelectrolyte Multilayer-Coated Particles for Biological Applications. In: Langmuir (in press), ,
n.n.khopade: nano. n.n.,