Prof. Dr. Alexey A. Bogdanov

Profile

Academic positionFull Professor
Research fieldsCell Biology,General Genetics, Functional Genome Research
KeywordsRibosomes, Signal transmission, rRNA, Ribosomal tunnel, Ribosomal antibiotics

Current contact address

CountryRussian Federation
CityMoscow
InstitutionMoscow M.V. Lomonosov State University
InstituteA.N. Belozersky Institute of Physico-Chemical Biology

Host during sponsorship

Dr. Richard BrimacombeMax-Planck-Institut für molekulare Genetik, Berlin
Prof. Dr. Knud H. NierhausMax-Planck-Institut für molekulare Genetik, Berlin
Start of initial sponsorship01/03/2001

Program(s)

2000Humboldt Research Award Programme

Nominator's project description

Prof. Bogdanov is a specialist in the study of the ribosome, the particle which - in every living cell - decodes the genetic information and synthesizes proteins. The atomic structure of a ribosome has recently been determined, and the task now facing researchers is to use this complex structural information to understand how the ribosome functions and how antibiotics are able to block it. Prof. Bogdanov plans to carry out such studies in Berlin, using the computer modelling facilities in R. Brimacombe's group (Max-Planck-Institut).

Publications (partial selection)

2002Alexey A. Bogdanov, Olga N. Avdeeva, Alexander G. Myasnikov, Petr V. Sergiev, Richard Brimacombe, Olga A. Dontsova: Construction of the 'minimal' SRP that interacts with the translating ribosome but not with specific membrane receptors in Escherichia coli. In: FEBS Letters, 2002, 70-73
2002Alexey A. Bogdanov et. al.: How does tmRNA move through the ribosome?. In: FEBS Letters, 2002, 55-59
2001Alexey A. Bogdanov, Andriy V. Kubarenko, Petr. V. Sergiev, Richard Brimacombe, Olga A. Dontsova: A protonated base pair participating in rRNA tertiary structural interactions. In: Nucleic Acids Research, 2001, 5067-5070