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Profile
| Academic position | Full Professor |
|---|---|
| Research fields | Pharmacology,Endocrinology, Diabetology, Metabolism |
| Keywords | SNARE proteins, glucose-mediated insulin release, pancreatic beta cell, exocytosis |
Current contact address
| Country | United States of America |
|---|---|
| City | Ithaca |
| Institution | Cornell University |
| Institute | Department of Molecular Medicine |
Host during sponsorship
| Prof. Dr. Reinhard Jahn | Abteilung Neurobiologie, Max-Planck-Institut für Multidisziplinäre Naturwissenschaften, Göttingen |
|---|---|
| Start of initial sponsorship | 01/05/2001 |
Programme(s)
| 2000 | Humboldt Research Award Programme |
|---|
Nominator's project description
| In his early days, Professor Sharp did groundbreaking work on circadian rythms and on the molecular basis of cholera. He is one of the leaders in the field of insulin secretion and diabetes. He discovered how inhibition of insulin secretion by endogeneous factors contributes to the genesis of diabetes. More recently, Professor Sharp has become interested in the molecular steps leading to insulin release. Since these steps appear to be similar in neurons where they are much better understood, he now will join forces with Reinhard Jahn in Göttingen. It is expected that the adaptation of techniques developed for neurons eill lead to fundamental and novel insights into the ways by which pancreatic islets relaese insulin and thus control blood glucose. |