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Profile
| Academic position | Full Professor |
|---|---|
| Research fields | Immunology,Reproductive Medicine, Urology |
| Keywords | Fehlgeburte, Präeklampsie, Schwangerschaft, Treg, Plazenta |
| Honours and awards | 2004: Rahel Hirsch Habilitation Fellow 2003: Alexander von Humboldt Fellow 2002: New Investigator Award, American Society for Reproductive Immunology 2000: DAAD Fellow |
Current contact address
| Country | Germany |
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| City | Leipzig |
| Institution | Helmholtz-Zentrum für Umweltforschung - UFZ |
| Institute | Department Umweltimmunologie |
Host during sponsorship
| Prof. Dr. Petra Arck | Biomedizinisches Forschungszentrum (BMFZ), Humboldt-Universität zu Berlin, Berlin |
|---|---|
| Start of initial sponsorship | 01/01/2002 |
Program(s)
| 2001 | Humboldt Research Fellowship Programme |
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Publications (partial selection)
| 2021 | Liebscher, L. and Weißenborn, C. and Langwisch, S. and Gohlke, B. O. and Preissner, R. and Rabinovich, G. A. and Christiansen, N. and Christiansen, H. and Zenclussen, A. C. and Fest, S. A minigene DNA vaccine encoding peptide epitopes derived from Galectin-1 has protective antitumoral effects in a model of neuroblastoma. In: Cancer Lett, 509, 2021, 105--114 |
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| 2021 | Schaffert, A. and Krieg, L. and Weiner, J. and Schlichting, R. and Ueberham, E. and Karkossa, I. and Bauer, M. and Landgraf, K. and Junge, K. M. and Wabitsch, M. and Lehmann, J. and Escher, B. I. and Zenclussen, A. C. and Körner, A. and Blüher, M. and Heiker, J. T. and von Bergen, M. and Schubert, K. Alternatives for the worse: Molecular insights into adverse effects of bisphenol a and substitutes during human adipocyte differentiation. In: Environ Int, 156, 2021, 106730 |
| 2021 | Jeschke, L. and Santamaria, C. G. and Meyer, N. and Zenclussen, A. C. and Bartley, J. and Schumacher, A. Early-pregnancy dydrogesterone supplementation mimicking luteal-phase support in ART patients did not provoke major reproductive disorders in pregnant mice and their progeny. In: Int J Mol Sci, 22, 2021, |
| 2021 | Wasserloos, A. and Thomassen, M. C. L. G. D. and Costa, S. D. and Zenclussen, A. and Tchaikovski, V. and Hackeng, T. M. and Stickeler, E. and Tchaikovski, S. N. Effect of blood loss during caesarean section on coagulation parameters. In: Thromb Res, 202, 2021, 84--89 |
| 2021 | Korthals, M. and Tech, L. and Langnaese, K. and Gottfried, A. and Hradsky, J. and Thomas, U. and Zenclussen, A. C. and Brunner-Weinzierl, M. C. and Tedford, K. and Fischer, K. D. Homeostasis in mice. In: Eur J Immunol, 51, 2021, 594--602 |
| 2021 | Busse, M. and Redlich, A. and Hartig, R. and Costa, S. D. and Rathert, H. and Fest, S. and Zenclussen, A. C. Imbalance between inflammatory and regulatory cord blood B cells following pre-term birth. In: J Reprod Immunol, 145, 2021, 103319 |
| 2021 | Luo, M. and Meehan, A. J. and Walton, E. and Röder, S. and Herberth, G. and Zenclussen, A. C. and Cosín-Tomás, M. and Sunyer, J. and Mulder, R. H. and Cortes Hidalgo, A. P. and Bakermans-Kranenburg, M. J. and Felix, J. F. and Relton, C. and Suderman, M. and Pappa, I. and Kok, R. and Tiemeier, H. and van IJzendoorn, M. H. and Barker, E. D. and Cecil, C. A. M. Neonatal DNA methylation and childhood low prosocial behavior: An epigenome-wide association meta-analysis. In: Am J Med Genet B Neuropsychiatr Genet, 186, 2021, 228--241 |
| 2020 | Dustin, M. L. and Zenclussen, A. C. A checkpoint cliffhanger at the dawn of placental mammals. In: J Biol Chem, 295, 2020, 4381--4382 |
| 2020 | Santamaria, C. G. and Meyer, N. and Schumacher, A. and Zenclussen, M. L. and Teglia, C. M. and Culzoni, M. J. and Zenclussen, A. C. and Rodriguez, H. A. Dermal exposure to the UV filter benzophenone-3 during early pregnancy affects fetal growth and sex ratio of the progeny in mice. In: Arch Toxicol, 94, 2020, 2847--2859 |
| 2020 | Anselmino, N. and Starbuck, M. and Labanca, E. and Cotignola, J. and Navone, N. and Gueron, G. and Zenclussen, A. C. and Vazquez, E. Heme oxygenase-1 is a pivotal modulator of bone turnover and remodeling: molecular implications for prostate cancer bone metastasis. In: Antioxid Redox Signal, 32, 2020, 1243--1258 |
| 2020 | Bank, U. and Deiser, K. and Plaza-Sirvent, C. and Osbelt, L. and Witte, A. and Knop, L. and Labrenz, R. and Jänsch, R. and Richter, F. and Biswas, A. and Zenclussen, A. C. and Vivier, E. and Romagnani, C. and Kühl, A. A. and Dunay, I. R. and Strowig, T. and Schmitz, I. and Schüler, T. ILC development and protection from intestinal inflammation in mice. In: Nat Commun, 11, 2020, 1056 |
| 2020 | Meyer, N. and Zenclussen, A. C. Immune cells in the uterine remodeling: are they the target of endocrine disrupting chemicals?. In: Front Immunol, 11, 2020, 246 |
| 2020 | Stojanovska, V. and Zenclussen, A. C. Innate and adaptive immune responses in HELLP syndrome. In: Front Immunol, 11, 2020, 667 |
| 2020 | Busse, M. and Campe, K. J. and Redlich, A. and Oettel, A. and Hartig, R. and Costa, S. D. and Zenclussen, A. C. Regulatory B cells are decreased and impaired in their function in peripheral maternal blood in pre-term birth. In: Front Immunol, 11, 2020, 386 |
| 2020 | Meyer, N. and Langwisch, S. and Scharm, M. and Zenclussen, A. C. Using ultrasound to define the time point of intrauterine growth retardation in a mouse model of heme oxygenase-1 deficiency. In: Biol Reprod, 103, 2020, 126--134 |
| 2020 | Meyer, N. and Schumacher, A. and Coenen, U. and Woidacki, K. and Schmidt, H. and Lindquist, J. A. and Mertens, P. R. and Zenclussen, A. C. Y-Box binding protein 1 expression in trophoblast cells promotes fetal and placental development. In: Cells, 9, 2020, |
| 2019 | Meyer, N. and Santamaria, C. G. and Müller, J. E. and Schumacher, A. and Rodriguez, H. A. and Zenclussen, A. C. Exposure to 17α-ethinyl estradiol during early pregnancy affects fetal growth and survival in mice. In: Environ Pollut, 251, 2019, 493--501 |
| 2019 | Ehrentraut, S. and Sauss, K. and Neumeister, R. and Luley, L. and Oettel, A. and Fettke, F. and Costa, S. D. and Langwisch, S. and Zenclussen, A. C. and Schumacher, A. Human miscarriage is associated with dysregulations in peripheral blood-derived myeloid dendritic cell subsets. In: Front Immunol, 10, 2019, 2440 |
| 2019 | Busse, M. and Campe, K. J. and Nowak, D. and Schumacher, A. and Plenagl, S. and Langwisch, S. and Tiegs, G. and Reinhold, A. and Zenclussen, A. C. IL-10 producing B cells rescue mouse fetuses from inflammation-driven fetal death and are able to modulate T cell immune responses. In: Sci Rep, 9, 2019, 9335 |
| 2019 | Dudeck, A. and Köberle, M. and Goldmann, O. and Meyer, N. and Dudeck, J. and Lemmens, S. and Rohde, M. and Roldán, N. G. and Dietze-Schwonberg, K. and Orinska, Z. and Medina, E. and Hendrix, S. and Metz, M. and Zenclussen, A. C. and von Stebut, E. and Biedermann, T. Mast cells as protectors of health. In: J Allergy Clin Immunol, 144, 2019, S4-S18 |
| 2019 | Luo, Y. and Meyer, N. and Jiao, Q. and Scheffel, J. and Zimmermann, C. and Metz, M. and Zenclussen, A. and Maurer, M. and Siebenhaar, F. Mice exhibit reduced numbers of mucosal mast cells. In: Front Immunol, 10, 2019, 2399 |
| 2019 | Santamaría, C. G. and Abud, J. E. and Porporato, M. M. and Meyer, N. and Zenclussen, A. C. and Kass, L. and Rodríguez, H. A. The UV filter benzophenone 3, alters early follicular assembly in rat whole ovary cultures. In: Toxicol Lett, 303, 2019, 48--54 |
| 2019 | Schumacher, A. and Zenclussen, A. C. human chorionic gonadotropin-mediated immune responses that facilitate embryo implantation and placentation. In: Front Immunol, 10, 2019, 2896 |
| 2018 | Müller, J. E. and Meyer, N. and Santamaria, C. G. and Schumacher, A. and Luque, E. H. and Zenclussen, M. L. and Rodriguez, H. A. and Zenclussen, A. C. Bisphenol A exposure during early pregnancy impairs uterine spiral artery remodeling and provokes intrauterine growth restriction in mice. In: Sci Rep, 8, 2018, 9196 |
| 2018 | Schumacher, A. and Ehrentraut, S. and Scharm, M. and Wang, H. and Hartig, R. and Morse, H. C. and Zenclussen, A. C. Cells harmful for the growing fetus. In: Front Immunol, 9, 2018, 1045 |
| 2018 | Ewert, L. and Fischer, A. and Brandt, S. and Scurt, F. G. and Philipsen, L. and Müller, A. J. and Girndt, M. and Zenclussen, A. C. and Lindquist, J. A. and Gorny, X. and Mertens, P. R. Cold shock Y-box binding protein-1 acetylation status in monocytes is associated with systemic inflammation and vascular damage. In: Atherosclerosis, 278, 2018, 156--165 |
| 2018 | Meyer, N. and Schüler, T. and Zenclussen, A. C. High frequency ultrasound for the analysis of fetal and placental development in vivo. In: J Vis Exp, 2018, |
| 2018 | Schumacher, A. and Sharkey, D. J. and Robertson, S. A. and Zenclussen, A. C. Immune cells at the fetomaternal interface: How the microenvironment modulates immune cells to foster fetal development. In: J Immunol, 201, 2018, 325--334 |
| 2018 | Consentius, C. and Mirenska, A. and Jurisch, A. and Reinke, S. and Scharm, M. and Zenclussen, A. C. and Hennig, C. and Volk, H. D. In situ detection of CD73+ CD90+ CD105+ lineage: Mesenchymal stromal cells in human placenta and bone marrow specimens by chipcytometry. In: Cytometry A, 93, 2018, 889--893 |
| 2018 | Meyer, N. and Zenclussen, A. C. Mast cells - good guys with a bad image?. In: Am J Reprod Immunol, 80, 2018, e13002 |
| 2018 | Sauss, K. and Ehrentraut, S. and Zenclussen, A. C. and Schumacher, A. The pregnancy hormone human chorionic gonadotropin differentially regulates plasmacytoid and myeloid blood dendritic cell subsets. In: Am J Reprod Immunol, 79, 2018, e12837 |
| 2017 | Ranjan, S. and Goihl, A. and Kohli, S. and Gadi, I. and Pierau, M. and Shahzad, K. and Gupta, D. and Bock, F. and Wang, H. and Shaikh, H. and Kähne, T. and Reinhold, D. and Bank, U. and Zenclussen, A. C. and Niemz, J. and Schnöder, T. M. and Brunner-Weinzierl, M. and Fischer, T. and Kalinski, T. and Schraven, B. and Luft, T. and Huehn, J. and Naumann, M. and Heidel, F. H. and Isermann, B. Activated protein C protects from GvHD via PAR2/PAR3 signalling in regulatory T-cells. In: Nat Commun, 8, 2017, 311 |
| 2017 | Meyer, N. and Woidacki, K. and Knöfler, M. and Meinhardt, G. and Nowak, D. and Velicky, P. and Pollheimer, J. and Zenclussen, A. C. Chymase-producing cells of the innate immune system are required for decidual vascular remodeling and fetal growth. In: Sci Rep, 7, 2017, 45106 |
| 2017 | Weissenborn, C. and Ignatov, T. and Nass, N. and Kalinski, T. and Dan Costa, S. and Zenclussen, A. C. and Ignatov, A. GPER promoter methylation controls GPER expression in breast cancer patients. In: Cancer Invest, 35, 2017, 100--107 |
| 2017 | Schumacher, A. and Dauven, D. and Zenclussen, A. C. Progesterone-driven local regulatory T cell induction does not prevent fetal loss in the CBA/J×DBA/2J abortion-prone model. In: Am J Reprod Immunol, 77, 2017, |
| 2017 | Meyer, N. and Woidacki, K. and Maurer, M. and Zenclussen, A. C. Safeguarding of fetal growth by mast cells and natural killer cells: Deficiency of one is counterbalanced by the other. In: Front Immunol, 8, 2017, 711 |
| 2017 | Meyer, N. and Schüler, T. and Zenclussen, A. C. Simultaneous ablation of uterine natural killer cells and uterine mast cells in mice leads to poor vascularization and abnormal Doppler measurements that compromise fetal well-being. In: Front Immunol, 8, 2017, 1913 |
| 2017 | Kohli, S. and Hoffmann, J. and Lochmann, F. and Markmeyer, P. and Huebner, H. and Fahlbusch, F. B. and Al-Dabet, M. M. and Gadi, I. and Manoharan, J. and Löttge, M. and Zenclussen, A. C. and Aharon, A. and Brenner, B. and Shahzad, K. and Ruebner, M. and Isermann, B. p45 NF-E2 regulates syncytiotrophoblast differentiation by post-translational GCM1 modifications in human intrauterine growth restriction. In: Cell Death Dis, 8, 2017, e2730 |
| 2016 | Spilker, C. and Nullmeier, S. and Grochowska, K. M. and Schumacher, A. and Butnaru, I. and Macharadze, T. and Gomes, G. M. and Yuanxiang, P. and Bayraktar, G. and Rodenstein, C. and Geiseler, C. and Kolodziej, A. and Lopez-Rojas, J. and Montag, D. and Angenstein, F. and Bär, J. and D'Hanis, W. and Roskoden, T. and Mikhaylova, M. and Budinger, E. and Ohl, F. W. and Stork, O. and Zenclussen, A. C. and Karpova, A. and Schwegler, H. and Kreutz, M. R. A Jacob/Nsmf gene knockout results in hippocampal dysplasia and impaired BDNF signaling in dendritogenesis. In: PLoS Genet, 12, 2016, e1005907 |
| 2016 | Oettel, A. and Lorenz, M. and Stangl, V. and Costa, S. D. and Zenclussen, A. C. and Schumacher, A. Human umbilical vein endothelial cells foster conversion of CD4+CD25-Foxp3- T cells into CD4+Foxp3+ regulatory T cells via transforming growth factor-β. In: Sci Rep, 6, 2016, 23278 |
| 2016 | Dauven, D. and Ehrentraut, S. and Langwisch, S. and Zenclussen, A. C. and Schumacher, A. Immune modulatory effects of human Chorionic Gonadotropin on dendritic cells supporting fetal survival in murine pregnancy. In: Front Endocrinol (Lausanne), 7, 2016, 146 |
| 2016 | Poloski, E. and Oettel, A. and Ehrentraut, S. and Luley, L. and Costa, S. D. and Zenclussen, A. C. and Schumacher, A. JEG-3 trophoblast cells producing human Chorionic Gonadotropin promote conversion of human CD4+FOXP3- T cells into CD4+FOXP3+ regulatory T cells and foster T cell suppressive activity. In: Biol Reprod, 94, 2016, 106 |
| 2016 | Fettke, F. and Schumacher, A. and Canellada, A. and Toledo, N. and Bekeredjian-Ding, I. and Bondt, A. and Wuhrer, M. and Costa, S. D. and Zenclussen, A. C. Maternal and fetal mechanisms of B cell regulation during pregnancy: Human chorionic Gonadotropin stimulates B cells to produce IL-10 while alpha-fetoprotein drives them into apoptosis. In: Front Immunol, 7, 2016, 495 |
| 2016 | Kohli, S. and Ranjan, S. and Hoffmann, J. and Kashif, M. and Daniel, E. A. and Al-Dabet, M. M. and Bock, F. and Nazir, S. and Huebner, H. and Mertens, P. R. and Fischer, K. D. and Zenclussen, A. C. and Offermanns, S. and Aharon, A. and Brenner, B. and Shahzad, K. and Ruebner, M. and Isermann, B. Maternal extracellular vesicles and platelets promote preeclampsia via inflammasome activation in trophoblasts. In: Blood, 128, 2016, 2153--2164 |
| 2016 | Bronchud, M. H. and Tresserra, F. and Xu, W. and Warren, S. and Cusido, M. and Zantop, B. and Zenclussen, A. C. and Cesano, A. Placental immune editing switch (PIES): learning about immunomodulatory pathways from a unique case report. In: Oncotarget, 7, 2016, 83817--83827 |
| 2016 | Fest, S. and Soldati, R. and Christiansen, N. M. and Zenclussen, M. L. and Kilz, J. and Berger, E. and Starke, S. and Lode, H. N. and Engel, C. and Zenclussen, A. C. and Christiansen, H. Targeting of heme oxygenase-1 as a novel immune regulator of neuroblastoma. In: Int J Cancer, 138, 2016, 2030--2042 |
| 2015 | Zenclussen, A. C. and Hämmerling, G. J. Cellular regulation of the uterine microenvironment that enables embryo implantation. In: Front Immunol, 6, 2015, 321 |
| 2015 | Wong, R. J. and Zenclussen, A. C. Editorial: Heme oxygenases: Novel regulators of reproductive processes. In: Front Pharmacol, 6, 2015, 282 |
| 2015 | Luley, L. and Schumacher, A. and Mulla, M. J. and Franke, D. and Löttge, M. and Fill Malfertheiner, S. and Tchaikovski, S. N. and Costa, S. D. and Hoppe, B. and Abrahams, V. M. and Zenclussen, A. C. Low molecular weight heparin modulates maternal immune response in pregnant women and mice with thrombophilia. In: Am J Reprod Immunol, 73, 2015, 417--427 |
| 2015 | Schumacher, A. and Zenclussen, A. C. The paternal contribution to fetal tolerance. In: Adv Exp Med Biol, 868, 2015, 211--225 |
| 2015 | Woidacki, K. and Meyer, N. and Schumacher, A. and Goldschmidt, A. and Maurer, M. and Zenclussen, A. C. Transfer of regulatory T cells into abortion-prone mice promotes the expansion of uterine mast cells and normalizes early pregnancy angiogenesis. In: Sci Rep, 5, 2015, 13938 |
| 2014 | Mikhaylova, M. and Schumacher, A. and Borutzki, C. and Neumann, J. R. and Macharadze, T. and El-Mousleh, T. and Wahle, P. and Zenclussen, A. C. and Kreutz, M. R. Analysis of Y-P30/Dermcidin expression and properties of the Y-P30 peptide. In: BMC Res Notes, 7, 2014, 400 |
| 2014 | Muzzio, D. O. and Soldati, R. and Ehrhardt, J. and Utpatel, K. and Evert, M. and Zenclussen, A. C. and Zygmunt, M. and Jensen, F. B cell development undergoes profound modifications and adaptations during pregnancy in mice. In: Biol Reprod, 91, 2014, 115 |
| 2014 | Fettke, F. and Schumacher, A. and Costa, S. D. and Zenclussen, A. C. B cells: the old new players in reproductive immunology. In: Front Immunol, 5, 2014, 285 |
| 2014 | Muzzio, D. O. and Soldati, R. and Rolle, L. and Zygmunt, M. and Zenclussen, A. C. and Jensen, F. B-1a B cells regulate T cell differentiation associated with pregnancy disturbances. In: Front Immunol, 5, 2014, 6 |
| 2014 | Landgraf, P. and Mikhaylova, M. and Macharadze, T. and Borutzki, C. and Zenclussen, A. C. and Wahle, P. and Kreutz, M. R. Binding of Y-P30 to syndecan 2/3 regulates the nuclear localization of CASK. In: PLoS One, 9, 2014, e85924 |
| 2014 | Linzke, N. and Schumacher, A. and Woidacki, K. and Croy, B. A. and Zenclussen, A. C. Carbon monoxide promotes proliferation of uterine natural killer cells and remodeling of spiral arteries in pregnant hypertensive heme oxygenase-1 mutant mice. In: Hypertension, 63, 2014, 580--588 |
| 2014 | Schumacher, A. and Costa, S. D. and Zenclussen, A. C. Endocrine factors modulating immune responses in pregnancy. In: Front Immunol, 5, 2014, 196 |
| 2014 | Weißenborn, C. and Ignatov, T. and Poehlmann, A. and Wege, A. K. and Costa, S. D. and Zenclussen, A. C. and Ignatov, A. GPER functions as a tumor suppressor in MCF-7 and SK-BR-3 breast cancer cells. In: J Cancer Res Clin Oncol, 140, 2014, 663--671 |
| 2014 | Weißenborn, C. and Ignatov, T. and Ochel, H. J. and Costa, S. D. and Zenclussen, A. C. and Ignatova, Z. and Ignatov, A. GPER functions as a tumor suppressor in triple-negative breast cancer cells. In: J Cancer Res Clin Oncol, 140, 2014, 713--723 |
| 2014 | Zenclussen, M. L. and Linzke, N. and Schumacher, A. and Fest, S. and Meyer, N. and Casalis, P. A. and Zenclussen, A. C. Heme oxygenase-1 is critically involved in placentation, spiral artery remodeling, and blood pressure regulation during murine pregnancy. In: Front Pharmacol, 5, 2014, 291 |
| 2014 | Zenclussen, M. L. and Casalis, P. A. and Jensen, F. and Woidacki, K. and Zenclussen, A. C. Hormonal fluctuations during the estrous cycle modulate Heme Oxygenase-1 expression in the uterus. In: Front Endocrinol (Lausanne), 5, 2014, 32 |
| 2014 | Teles, A. and Zenclussen, A. C. How cells of the immune system prepare the endometrium for implantation. In: Semin Reprod Med, 32, 2014, 358--364 |
| 2014 | Schmerse, F. and Woidacki, K. and Riek-Burchardt, M. and Reichardt, P. and Roers, A. and Tadokoro, C. and Zenclussen, A. C. In vivo visualization of uterine mast cells by two-photon microscopy. In: Reproduction, 147, 2014, 781--788 |
| 2014 | Schumacher, A. and Poloski, E. and Spörke, D. and Zenclussen, A. C. Luteinizing hormone contributes to fetal tolerance by regulating adaptive immune responses. In: Am J Reprod Immunol, 71, 2014, 434--440 |
| 2014 | Woidacki, K. and Zenclussen, A. C. and Siebenhaar, F. Mast cell-mediated and associated disorders in pregnancy: a risky game with an uncertain outcome?. In: Front Immunol, 5, 2014, 231 |
| 2014 | Schumacher, A. and Zenclussen, A. C. Regulatory T cells: regulators of life. In: Am J Reprod Immunol, 72, 2014, 158--170 |
| 2014 | Schumacher, A. and Zenclussen, A. C. effects of heme oxygenase-1 on innate and adaptive immune responses promoting pregnancy success and allograft tolerance. In: Front Pharmacol, 5, 2014, 288 |
| 2013 | Zenclussen, A. C. Adaptive immune responses during pregnancy. In: Am J Reprod Immunol, 69, 2013, 291--303 |
| 2013 | Teles, A. and Schumacher, A. and Kühnle, M. C. and Linzke, N. and Thuere, C. and Reichardt, P. and Tadokoro, C. E. and Hämmerling, G. J. and Zenclussen, A. C. Control of uterine microenvironment by Foxp3(+) cells facilitates embryo implantation. In: Front Immunol, 4, 2013, 158 |
| 2013 | Rolle, L. and Memarzadeh Tehran, M. and Morell-García, A. and Raeva, Y. and Schumacher, A. and Hartig, R. and Costa, S. D. and Jensen, F. and Zenclussen, A. C. Cutting edge: IL-10-producing regulatory B cells in early human pregnancy. In: Am J Reprod Immunol, 70, 2013, 448--453 |
| 2013 | Ignatov, T. and Modl, S. and Thulig, M. and Weißenborn, C. and Treeck, O. and Ortmann, O. and Zenclussen, A. and Costa, S. D. and Kalinski, T. and Ignatov, A. GPER-1 acts as a tumor suppressor in ovarian cancer. In: J Ovarian Res, 6, 2013, 51 |
| 2013 | Kahlo, K. and Fill Malfertheiner, S. and Ignatov, T. and Jensen, F. and Costa, S. D. and Schumacher, A. and Zenclussen, A. C. HO-1 as modulator of the innate immune response in pregnancy. In: Am J Reprod Immunol, 70, 2013, 24--30 |
| 2013 | Schumacher, A. and Heinze, K. and Witte, J. and Poloski, E. and Linzke, N. and Woidacki, K. and Zenclussen, A. C. Human chorionic gonadotropin as a central regulator of pregnancy immune tolerance. In: J Immunol, 190, 2013, 2650--2658 |
| 2013 | Zenclussen, A. C. and Olivieri, D. N. and Dustin, M. L. and Tadokoro, C. E. In vivo multiphoton microscopy technique to reveal the physiology of the mouse uterus. In: Am J Reprod Immunol, 69, 2013, 281--289 |
| 2013 | Woidacki, K. and Jensen, F. and Zenclussen, A. C. Mast cells as novel mediators of reproductive processes. In: Front Immunol, 4, 2013, 29 |
| 2013 | Woidacki, K. and Popovic, M. and Metz, M. and Schumacher, A. and Linzke, N. and Teles, A. and Poirier, F. and Fest, S. and Jensen, F. and Rabinovich, G. A. and Maurer, M. and Zenclussen, A. C. Mast cells rescue implantation defects caused by c-kit deficiency. In: Cell Death Dis, 4, 2013, e462 |
| 2013 | Teles, A. and Thuere, C. and Wafula, P. O. and El-Mousleh, T. and Zenclussen, M. L. and Zenclussen, A. C. Origin of Foxp3(+) cells during pregnancy. In: Am J Clin Exp Immunol, 2, 2013, 222--233 |
| 2013 | Jensen, F. and Muzzio, D. and Soldati, R. and Fest, S. and Zenclussen, A. C. Regulatory B10 cells restore pregnancy tolerance in a mouse model. In: Biol Reprod, 89, 2013, 90 |
| 2013 | Teles, A. and Zenclussen, A. C. and Schumacher, A. Regulatory T cells are baby's best friends. In: Am J Reprod Immunol, 69, 2013, 331--339 |
| 2013 | Berger, E. and Soldati, R. and Huebener, N. and Hohn, O. and Stermann, A. and Durmus, T. and Lobitz, S. and Zenclussen, A. C. and Christiansen, H. and Lode, H. N. and Fest, S. Salmonella SL7207 application is the most effective DNA vaccine delivery method for successful tumor eradication in a murine model for neuroblastoma. In: Cancer Lett, 331, 2013, 167--173 |
| 2013 | Muzzio, D. and Zenclussen, A. C. and Jensen, F. The role of B cells in pregnancy: the good and the bad. In: Am J Reprod Immunol, 69, 2013, 408--412 |
| 2013 | Panayotova-Dimitrova, D. and Feoktistova, M. and Ploesser, M. and Kellert, B. and Hupe, M. and Horn, S. and Makarov, R. and Jensen, F. and Porubsky, S. and Schmieder, A. and Zenclussen, A. C. and Marx, A. and Kerstan, A. and Geserick, P. and He, Y. W. and Leverkus, M. cFLIP regulates skin homeostasis and protects against TNF-induced keratinocyte apoptosis. In: Cell Rep, 5, 2013, 397--408 |
| 2012 | Schumacher, A. and Wafula, P. O. and Teles, A. and El-Mousleh, T. and Linzke, N. and Zenclussen, M. L. and Langwisch, S. and Heinze, K. and Wollenberg, I. and Casalis, P. A. and Volk, H. D. and Fest, S. and Zenclussen, A. C. Blockage of heme oxygenase-1 abrogates the protective effect of regulatory T cells on murine pregnancy and promotes the maturation of dendritic cells. In: PLoS One, 7, 2012, e42301 |
| 2012 | Jensen, F. and Wallukat, G. and Herse, F. and Budner, O. and El-Mousleh, T. and Costa, S. D. and Dechend, R. and Zenclussen, A. C. CD19+CD5+ cells as indicators of preeclampsia. In: Hypertension, 59, 2012, 861--868 |
| 2012 | El-Mousleh, T. and Casalis, P. A. and Wollenberg, I. and Zenclussen, M. L. and Volk, H. D. and Langwisch, S. and Jensen, F. and Zenclussen, A. C. Exploring the potential of low doses carbon monoxide as therapy in pregnancy complications. In: Med Gas Res, 2, 2012, 4 |
| 2012 | Zenclussen, M. L. and Jensen, F. and Rebelo, S. and El-Mousleh, T. and Casalis, P. A. and Zenclussen, A. C. Heme oxygenase-1 expression in the ovary dictates a proper oocyte ovulation, fertilization, and corpora lutea maintenance. In: Am J Reprod Immunol, 67, 2012, 376--382 |
| 2012 | Zenclussen, A. C. and Olivieri, D. N. and Dustin, M. L. and Tadokoro, C. E. In vivo multiphoton microscopy technique to reveal the physiology of the mouse placenta. In: Am J Reprod Immunol, 68, 2012, 271--278 |
| 2012 | Soldati, R. and Berger, E. and Zenclussen, A. C. and Jorch, G. and Lode, H. N. and Salatino, M. and Rabinovich, G. A. and Fest, S. Neuroblastoma triggers an immunoevasive program involving galectin-1-dependent modulation of T cell and dendritic cell compartments. In: Int J Cancer, 131, 2012, 1131--1141 |
| 2012 | Zierau, O. and Zenclussen, A. C. and Jensen, F. Role of female sex hormones, estradiol and progesterone, in mast cell behavior. In: Front Immunol, 3, 2012, 169 |
| 2012 | Woudwyk, M. A. and Monteavaro, C. E. and Jensen, F. and Soto, P. and Barbeito, C. G. and Zenclussen, A. C. Study of the uterine local immune response in a murine model of embryonic death due to tritrichomonas foetus. In: Am J Reprod Immunol, 68, 2012, 128--137 |
| 2011 | Zenclussen, M. L. and Casalis, P. A. and El-Mousleh, T. and Rebelo, S. and Langwisch, S. and Linzke, N. and Volk, H. D. and Fest, S. and Soares, M. P. and Zenclussen, A. C. Haem oxygenase-1 dictates intrauterine fetal survival in mice via carbon monoxide. In: J Pathol, 225, 2011, 293--304 |
| 2011 | Leber, A. and Zenclussen, M. L. and Teles, A. and Brachwitz, N. and Casalis, P. and El-Mousleh, T. and Jensen, F. and Woidacki, K. and Zenclussen, A. C. Pregnancy: tolerance and suppression of immune responses. In: Methods Mol Biol, 677, 2011, 397--417 |
| 2010 | Jensen, F. and Woudwyk, M. and Teles, A. and Woidacki, K. and Taran, F. and Costa, S. and Malfertheiner, S. F. and Zenclussen, A. C. Estradiol and progesterone regulate the migration of mast cells from the periphery to the uterus and induce their maturation and degranulation. In: PLoS One, 5, 2010, e14409 |
| 2010 | Leber, A. and Teles, A. and Zenclussen, A. C. Regulatory T cells and their role in pregnancy. In: Am J Reprod Immunol, 63, 2010, 445--459 |
| 2010 | Huang, S. J. and Zenclussen, A. C. and Chen, C. P. and Basar, M. and Yang, H. and Arcuri, F. and Li, M. and Kocamaz, E. and Buchwalder, L. and Rahman, M. and Kayisli, U. and Schatz, F. and Toti, P. and Lockwood, C. J. The implication of aberrant GM-CSF expression in decidual cells in the pathogenesis of preeclampsia. In: Am J Pathol, 177, 2010, 2472--2482 |
| 2010 | Zenclussen, M. L. and Thuere, C. and Ahmad, N. and Wafula, P. O. and Fest, S. and Teles, A. and Leber, A. and Casalis, P. A. and Bechmann, I. and Priller, J. and Volk, H. D. and Zenclussen, A. C. The persistence of paternal antigens in the maternal body is involved in regulatory T-cell expansion and fetal-maternal tolerance in murine pregnancy. In: Am J Reprod Immunol, 63, 2010, 200--208 |
| 2009 | Schumacher, A. and Brachwitz, N. and Sohr, S. and Engeland, K. and Langwisch, S. and Dolaptchieva, M. and Alexander, T. and Taran, A. and Malfertheiner, S. F. and Costa, S. D. and Zimmermann, G. and Nitschke, C. and Volk, H. D. and Alexander, H. and Gunzer, M. and Zenclussen, A. C. Human chorionic gonadotropin attracts regulatory T cells into the fetal-maternal interface during early human pregnancy. In: J Immunol, 182, 2009, 5488--5497 |
| 2009 | Wafula, P. O. and Teles, A. and Schumacher, A. and Pohl, K. and Yagita, H. and Volk, H. D. and Zenclussen, A. C. PD-1 but not CTLA-4 blockage abrogates the protective effect of regulatory T cells in a pregnancy murine model. In: Am J Reprod Immunol, 62, 2009, 283--292 |
| 2009 | Fest, S. and Huebener, N. and Bleeke, M. and Durmus, T. and Stermann, A. and Woehler, A. and Baykan, B. and Zenclussen, A. C. and Michalsky, E. and Jaeger, I. S. and Preissner, R. and Hohn, O. and Weixler, S. and Gaedicke, G. and Lode, H. N. Survivin minigene DNA vaccination is effective against neuroblastoma. In: Int J Cancer, 125, 2009, 104--114 |
| 2008 | Zenclussen, A. C. and Kökény, G. and Thimm, O. and Sollwedel, A. and Godo, M. and Casalis, P. A. and Zenclussen, M. L. and Volk, H. D. and Hamar, P. Mechanisms behind flare of renal lupus during murine pregnancy. In: Reprod Biomed Online, 17, 2008, 114--126 |
| 2008 | Gratze, P. and Dechend, R. and Stocker, C. and Park, J. K. and Feldt, S. and Shagdarsuren, E. and Wellner, M. and Gueler, F. and Rong, S. and Gross, V. and Obst, M. and Plehm, R. and Alenina, N. and Zenclussen, A. and Titze, J. and Small, K. and Yokota, Y. and Zenke, M. and Luft, F. C. and Muller, D. N. Novel role for inhibitor of differentiation 2 in the genesis of angiotensin II-induced hypertension. In: Circulation, 117, 2008, 2645--2656 |
| 2008 | Fest, S. and Brachwitz, N. and Schumacher, A. and Zenclussen, M. L. and Khan, F. and Wafula, P. O. and Casalis, P. A. and Fill, S. and Costa, S. D. and Mor, G. and Volk, H. D. and Lode, H. N. and Zenclussen, A. C. Supporting the hypothesis of pregnancy as a tumor: survivin is upregulated in normal pregnant mice and participates in human trophoblast proliferation. In: Am J Reprod Immunol, 59, 2008, 75--83 |
| 2007 | Zenclussen, A. C. and Schumacher, A. and Zenclussen, M. L. and Wafula, P. and Volk, H. D. Immunology of pregnancy: cellular mechanisms allowing fetal survival within the maternal uterus. In: Expert Rev Mol Med, 9, 2007, 1--14 |
| 2007 | Thuere, C. and Zenclussen, M. L. and Schumacher, A. and Langwisch, S. and Schulte-Wrede, U. and Teles, A. and Paeschke, S. and Volk, H. D. and Zenclussen, A. C. Kinetics of regulatory T cells during murine pregnancy. In: Am J Reprod Immunol, 58, 2007, 514--523 |
| 2007 | Schumacher, A. and Wafula, P. O. and Bertoja, A. Z. and Sollwedel, A. and Thuere, C. and Wollenberg, I. and Yagita, H. and Volk, H. D. and Zenclussen, A. C. Mechanisms of action of regulatory T cells specific for paternal antigens during pregnancy. In: Obstet Gynecol, 110, 2007, 1137--1145 |
| 2007 | Schmid, M. and Sollwedel, A. and Thuere, C. and Wafula, P. O. and Zenclussen, M. L. and Müller, D. N. and Gratze, P. and Woiciechowsky, C. and Volk, H. D. and Zenclussen, A. C. Murine pre-eclampsia induced by unspecific activation of the immune system correlates with alterations in the eNOS and AT1 receptor expression in the kidneys and placenta. In: Placenta, 28, 2007, 688--700 |
| 2007 | Kökény, G. and Godó, M. and Nagy, E. and Kardos, M. and Kotsch, K. and Casalis, P. and Bodor, C. and Rosivall, L. and Volk, H. D. and Zenclussen, A. C. and Hamar, P. Skin disease is prevented but nephritis is accelerated by multiple pregnancies in autoimmune MRL/LPR mice. In: Lupus, 16, 2007, 465--477 |
| 2006 | Zenclussen, A. C. A novel mouse model for preeclampsia by transferring activated th1 cells into normal pregnant mice. In: Methods Mol Med, 122, 2006, 401--412 |
| 2006 | Zenclussen, M. L. and Anegon, I. and Bertoja, A. Z. and Chauveau, C. and Vogt, K. and Gerlof, K. and Sollwedel, A. and Volk, H. D. and Ritter, T. and Zenclussen, A. C. Over-expression of heme oxygenase-1 by adenoviral gene transfer improves pregnancy outcome in a murine model of abortion. In: J Reprod Immunol, 69, 2006, 35--52 |
| 2006 | Zenclussen, A. C. Regulatory T cells in pregnancy. In: Springer Semin Immunopathol, 28, 2006, 31--39 |
| 2006 | Zenclussen, A. C. and Gerlof, K. and Zenclussen, M. L. and Ritschel, S. and Zambon Bertoja, A. and Fest, S. and Hontsu, S. and Ueha, S. and Matsushima, K. and Leber, J. and Volk, H. D. Regulatory T cells induce a privileged tolerant microenvironment at the fetal-maternal interface. In: Eur J Immunol, 36, 2006, 82--94 |
| 2006 | Fest, S. and Zenclussen, A. C. and Joachim, R. and Hagen, E. and Demuth, H. U. and Hoffmann, T. Stress and substance P but not the substance P-metabolite SP5-11 trigger murine abortion by augmenting TNF-alpha levels at the feto-maternal interface. In: Scand J Immunol, 63, 2006, 42--49 |
| 2005 | Bertoja, A. Z. and Zenclussen, M. L. and Casalis, P. A. and Sollwedel, A. and Schumacher, A. and Woiciechowsky, C. and Volk, H. D. and Zenclussen, A. C. Anti-P- and E-selectin therapy prevents abortion in the CBA/J x DBA/2J combination by blocking the migration of Th1 lymphocytes into the foetal-maternal interface. In: Cell Immunol, 238, 2005, 97--102 |
| 2005 | Zenclussen, A. C. CD4(+)C25+ T regulatory cells in murine pregnancy. In: J Reprod Immunol, 65, 2005, 101--110 |
| 2005 | Zenclussen, A. C. and Sollwedel, A. and Bertoja, A. Z. and Gerlof, K. and Zenclussen, M. L. and Woiciechowsky, C. and Volk, H. D. Heme oxygenase as a therapeutic target in immunological pregnancy complications. In: Int Immunopharmacol, 5, 2005, 41--51 |
| 2005 | Paeschke, S. and Chen, F. and Horn, N. and Fotopoulou, C. and Zambon-Bertoja, A. and Sollwedel, A. and Zenclussen, M. L. and Casalis, P. A. and Dudenhausen, J. W. and Volk, H. D. and Zenclussen, A. C. Pre-eclampsia is not associated with changes in the levels of regulatory T cells in peripheral blood. In: Am J Reprod Immunol, 54, 2005, 384--389 |
| 2005 | Sollwedel, A. and Bertoja, A. Z. and Zenclussen, M. L. and Gerlof, K. and Lisewski, U. and Wafula, P. and Sawitzki, B. and Woiciechowsky, C. and Volk, H. D. and Zenclussen, A. C. Protection from abortion by heme oxygenase-1 up-regulation is associated with increased levels of Bag-1 and neuropilin-1 at the fetal-maternal interface. In: J Immunol, 175, 2005, 4875--4885 |
| 2005 | Zenclussen, A. C. and Zenclussen, M. L. and Ritter, T. and Volk, H. D. The use of gene therapy tools in reproductive immunology research. In: Curr Gene Ther, 5, 2005, 459--466 |
| 2005 | Bertoja, A. Z. and Zenclussen, M. L. and Wollenberg, I. and Paeschke, S. and Sollwedel, A. and Gerlof, K. and Woiciechowsky, C. and Volk, H. D. and Zenclussen, A. C. Upregulation of Bcl-2 at the foetal-maternal interface from mice undergoing abortion. In: Scand J Immunol, 61, 2005, 492--502 |
| 2005 | Zenclussen, A. C. and Gerlof, K. and Zenclussen, M. L. and Sollwedel, A. and Bertoja, A. Z. and Ritter, T. and Kotsch, K. and Leber, J. and Volk, H. D. Ábnormal T-cell reactivity against paternal antigens in spontaneous abortion: adoptive transfer of pregnancy-induced CD4+CD25+ T regulatory cells prevents fetal rejection in a murine abortion model. In: Am J Pathol, 166, 2005, 811--822 |
| 2004 | Blois, S. and Zenclussen, A. C. and Roux, M. E. and Olmos, S. and di Conza, J. and Arck, P. C. and Margni, R. A. A symmetric antibodies (AAb) in the female reproductive tract. In: J Reprod Immunol, 64, 2004, 31--43 |
| 2004 | Sehmsdorf, U. S. and Zenclussen, A. C. and Arck, P. and Hertwig, K. and Joachim, R. A. and Klapp, B. and Hildebrandt, M. O. Human miscarriage is associated with increased number of CD26 decidual lymphocytes. In: Scand J Immunol, 59, 2004, 400--407 |
| 2004 | Frewert, S. and Stockhammer, F. and Warschewske, G. and Zenclussen, A. C. and Rupprecht, S. and Volk, H. D. and Woiciechowsky, C. Intratumoral infusion of interleukin-1beta and interferon-gamma induces tumor invasion with macrophages and lymphocytes in a rat glioma model. In: Neurosci Lett, 364, 2004, 145--148 |
| 2004 | Zenclussen, A. C. and Fest, S. and Joachim, R. and Klapp, B. F. and Arck, P. C. Introducing a mouse model for pre-eclampsia: adoptive transfer of activated Th1 cells leads to pre-eclampsia-like symptoms exclusively in pregnant mice. In: Eur J Immunol, 34, 2004, 377--387 |
| 2004 | Tometten, M. and Klapp, B. F. and Joachim, R. and Fest, S. and Zenclussen, A. C. and Peters, E. M. and Hertwig, K. and Arck, P. C. Nerve growth factor and its functional receptor TrkA are up-regulated in murine decidual tissue of stress-triggered and substance P-mediated abortion. In: Am J Reprod Immunol, 51, 2004, 86--93 |
| 2003 | Zenclussen, A. C. and Lim, E. and Knoeller, S. and Knackstedt, M. and Hertwig, K. and Hagen, E. and Klapp, B. F. and Arck, P. C. Heme oxygenases in pregnancy II: HO-2 is downregulated in human pathologic pregnancies. In: Am J Reprod Immunol, 50, 2003, 66--76 |
| 2003 | Zenclussen, A. C. and Blois, S. and Stumpo, R. and Olmos, S. and Arias, K. and Malan Borel, I. and Roux, M. E. and Margni, R. A. Murine abortion is associated with enhanced interleukin-6 levels at the feto-maternal interface. In: Cytokine, 24, 2003, 150--160 |
| 2003 | Knackstedt, M. K. and Zenclussen, A. C. and Hertwig, K. and Hagen, E. and Dudenhausen, J. W. and Clark, D. A. and Arck, P. C. Th1 cytokines and the prothrombinase fgl2 in stress-triggered and inflammatory abortion. In: Am J Reprod Immunol, 49, 2003, 210--220 |
| 2003 | Joachim, R. and Zenclussen, A. C. and Polgar, B. and Douglas, A. J. and Fest, S. and Knackstedt, M. and Klapp, B. F. and Arck, P. C. The progesterone derivative dydrogesterone abrogates murine stress-triggered abortion by inducing a Th2 biased local immune response. In: Steroids, 68, 2003, 931--940 |
| 2002 | Zenclussen, A. C. and Joachim, R. and Hagen, E. and Peiser, C. and Klapp, B. F. and Arck, P. C. Heme oxygenase is downregulated in stress-triggered and interleukin-12-mediated murine abortion. In: Scand J Immunol, 55, 2002, 560--569 |
| 2002 | Canellada, A. and Färber, A. and Zenclussen, A. C. and Gentile, T. and Dokmetjian, J. and Keil, A. and Blois, S. and Miranda, S. and Berod, L. and Gutiérrez, G. and Markert, U. R. and Margni, R. A. Interleukin regulation of asymmetric antibody synthesized by isolated placental B cells. In: Am J Reprod Immunol, 48, 2002, 275--282 |
| 2002 | Zenclussen, A. C. and Fest, S. and Busse, P. and Joachim, R. and Klapp, B. F. and Arck, P. C. Questioning the Th1/Th2 paradigm in reproduction: peripheral levels of IL-12 are down-regulated in miscarriage patients. In: Am J Reprod Immunol, 48, 2002, 245--251 |
| 2001 | Zenclussen, A. C. and Gentile, T. and Kortebani, G. and Mazzolli, A. and Margni, R. Asymmetric antibodies and pregnancy. In: Am J Reprod Immunol, 45, 2001, 289--294 |
| 2001 | Margni, R. A. and Zenclussen, A. C. During pregnancy, in the context of a Th2-type cytokine profile, serum IL-6 levels might condition the quality of the synthesized antibodies. In: Am J Reprod Immunol, 46, 2001, 181--187 |
| 2001 | Zenclussen, A. C. and Fest, S. and Sehmsdorf, U. S. and Hagen, E. and Klapp, B. F. and Arck, P. C. Upregulation of decidual P-selectin expression is associated with an increased number of Th1 cell populations in patients suffering from spontaneous abortions. In: Cell Immunol, 213, 2001, 94--103 |
| 2000 | Zenclussen, A. C. and Kortebani, G. and Mazzolli, A. and Margni, R. and Malan Borel, I. Interleukin-6 and soluble interleukin-6 receptor serum levels in recurrent spontaneous abortion women immunized with paternal white cells. In: Am J Reprod Immunol, 44, 2000, 22--29 |