Prof. Dr. Maja Rupnik

Profile

Academic positionAssociate Professor, Senior Lecturer, Reader
Research fieldsMicrobial Ecology and Applied Microbiology,Medical Microbiology, Mycology and Hygiene, Molecular Infection Biology
Keywordsmolecular epidemiology, gut microbiota, NGS and WGS, microbiology

Current contact address

CountrySlovenia
CityMaribor
InstitutionNational Laboratory of Health, Environment and Food (NLZOH)
InstituteCentre of Medical Microbiology, Department of Microbiological Research

Host during sponsorship

Prof. Dr. Hans-Dieter SölingAbteilung Neurobiologie, Max-Planck-Institut für Multidisziplinäre Naturwissenschaften, Göttingen
Prof. Dr. Uwe GroßUniversity Medical Center Göttingen, Georg-August-Universität Göttingen, Göttingen
Start of initial sponsorship01/09/2001

Programme(s)

2001Humboldt Research Fellowship Programme

Publications (partial selection)

2019High Clostridium difficile contamination rates of domestic and imported potatoes compared to some other vegetables in Slovenia.: Tkalec V, Janezic S, Skok B, Simonic T, Mesaric S, Vrabic T, Rupnik M. . In: Food Microbiol., 2019, 194-200
2018Oren A, Rupnik M.: Clostridium difficile and Clostridioides difficile: Two validly published and correct names.. In: Anaerobe, 2018, 125-126
2018Horvat S, Rupnik M.: Interactions Between Clostridioides difficile and Fecal Microbiota in in Vitro Batch Model: Growth, Sporulation, and Microbiota Changes. . In: Front Microbiol, 2018, 1633
2018Bletz S, Janezic S, Harmsen D, Rupnik M, Mellmann A. Defining and Evaluating a Core Genome Multilocus Sequence Typing Scheme for Genome-Wide Typing of Clostridium difficile.. In: J Clin Microbiol, 2018,
2018Mahnic A, Rupnik M. Different host factors are associated with patterns in bacterial and fungal gut microbiota in Slovenian healthy cohort. . In: PLoS One., 2018, e0209209
2018Rodriguez Diaz C, Seyboldt C, Rupnik M. Non-human C. difficile Reservoirs and Sources: Animals, Food, Environment. . In: Adv Exp Med Biol., 2018, 227-243
2018Seugendo M, Janssen I, Lang V, Hasibuan I, Bohne W, Cooper P, Daniel R, Gunka K, Kusumawati RL, Mshana SE, von Müller L, Okamo B, Ortlepp JR, Overmann J, Riedel T, Rupnik M, Zimmermann O, Groß U. Prevalence and Strain Characterization of Clostridioides (Clostridium) difficile in Representative Regions of Germany, Ghana, Tanzania and Indonesia - A Comparative Multi-Center Cross-Sectional Study. . In: Front Microbiol, 2018, 1843
2018Knetsch CW, Kumar N, Forster SC, Connor TR, Browne HP, Harmanus C, Sanders IM, Harris SR, Turner L, Morris T, Perry M, Miyajima F, Roberts P, Pirmohamed M, Songer JG, Weese JS, Indra A, Corver J, Rupnik M, Wren BW, Riley TV, Kuijper EJ, Lawley TD.: Zoonotic Transfer of Clostridium difficile Harboring Antimicrobial Resistance between Farm Animals and Humans. In: J Clin Microbiol, 2018, e01384
2017Horvat S, Mahnic A, Breskvar M, Dzeroski S, Rupnik M. Evaluating the effect of Clostridium difficile conditioned medium on fecal microbiota community structure. . In: Sci Rep., 2017, 16448
2017Golle A, Janezic S, Rupnik M. Low overlap between carbapenem resistant Pseudomonas aeruginosa genotypes isolated from hospitalized patients and wastewater treatment plants. . In: PLoS One, 2017, e0186736
2016Tr?ek J, Mahni? A, Rupnik M.: Diversity of the microbiota involved in wine and organic apple cider submerged vinegar production as revealed by DHPLC analysis and next-generation sequencing. . In: Int J Food Microbiol., 2016, 57-62
2016Janssen I, Cooper P, Gunka K, Rupnik M, Wetzel D, Zimmermann O, Groß U.: High prevalence of nontoxigenic Clostridium difficile isolated from hospitalized and non-hospitalized individuals in rural Ghana. . In: Int J Med Microbiol., 2016, 652-656
2016Rupnik M, Janezic S. An Update on Clostridium difficile Toxinotyping. . In: J Clin Microbiol., 2016, 13-18
2016Janezic S, Potocnik M, Zidaric V, Rupnik M. Highly Divergent Clostridium difficile Strains Isolated from the Environment. 2016 Nov 23;11(11):. . In: PLoS One., 2016, e0167101
2016Bandelj P, Blagus R, Briski F, Frlic O, Vergles Rataj A, Rupnik M, Ocepek M, Vengust M.: Identification of risk factors influencing Clostridium difficile prevalence in middle-size dairy farms.. In: Vet Res, 2016, 41
2016Distribution of Clostridium difficile PCR ribotypes and high proportion of 027 and 176 in some hospitals in four South Eastern European countries.: Rupnik M, Tambic Andrasevic A, Trajkovska Dokic E, Matas I, Jovanovic M, Pasic S, Kocuvan A, Janezic S. . 2016 Dec;42:142-144.. In: Anaerobe, 2016, 142-144
2016Zidaric V, Rupnik M. Sporulation properties and antimicrobial susceptibility in endemic and rare Clostridium difficile PCR ribotypes. . In: Anaerobe. , 2016, 183-188
2015Janezic S, Marín M, Martín A, Rupnik M.: A new type of toxin A-negative, toxin B-positive Clostridium difficile strain lacking a complete tcdA gene. . In: J Clin Microbiol. , 2015, 692-695
2015Dermota U, Mueller-Premru M, Švent-Ku?ina N, Petrovi? Ž, Ribi? H, Rupnik M, Janeži? S, Zdovc I, Grmek-Košnik I.: Survey of community-associated-methicillin-Resistant Staphylococcus aureus in Slovenia: identification of community-associated and livestock-associated clones. . In: Int J Med Microbiol. , 2015, 505-510
2015Dermota U, Zdovc I, Strumbelj I, Grmek-Kosnik I, Ribic H, Rupnik M, Golob M, Zajc U, Bes M, Laurent F, Mueller-Premru M. Detection of methicillin-resistant Staphylococcus aureus carrying the mecC gene in human samples in Slovenia. . In: Epidemiol Infect. , 2015, 1105-1108
2015Janezic S, Rupnik M. Genomic diversity of Clostridium difficile strains. . In: Res Microbiol., 2015, 353-360
2015Walter BM, Cartman ST, Minton NP, Butala M, Rupnik M.: The SOS Response Master Regulator LexA Is Associated with Sporulation, Motility and Biofilm Formation in Clostridium difficile. In: PLoS One., 2015, e0144763.
2015Rupnik M. Toward a true bacteriotherapy for Clostridium difficile infection. . In: N Engl J Med., 2015, 1566-1568
2014Gerding DN, Johnson S, Rupnik M, Aktories K.: Clostridium difficile binary toxin CDT: mechanism, epidemiology, and potential clinical importance.. In: Gut Microbes, 2014, 15-27
2014Janezic S, Zidaric V, Pardon B, Indra A, Kokotovic B, Blanco JL, Seyboldt C, Diaz CR, Poxton IR, Perreten V, Drigo I, Jiraskova A, Ocepek M, Weese JS, Songer JG, Wilcox MH, Rupnik M. International Clostridium difficile animal strain collection and large diversity of animal associated strains. In: BMC Microbiol, 2014, 173
2014Walter BM, Rupnik M, Hodnik V, Anderluh G, Dupuy B, Pauli? N, Žgur-Bertok D, Butala M. The LexA regulated genes of the Clostridium difficile. . In: BMC Microbiol., 2014, 88
2014Davies KA, Longshaw CM, Davis GL, Bouza E, Barbut F, Barna Z, Delmée M, Fitzpatrick F, Ivanova K, Kuijper E, Macovei IS, Mentula S, Mastrantonio P, von Müller L, Oleastro M, Petinaki E, Pituch H, Norén T, Nováková E, Ny? O, Rupnik M, Schmid D, Wilcox MH. . 2014 Dec;14(12):1208-19.: Underdiagnosis of Clostridium difficile across Europe: the European, multicentre, prospective, biannual, point-prevalence study of Clostridium difficile infection in hospitalised patients with diarrhoea (EUCLID). . In: Lancet Infect Dis, 2014, 1208-1219
2009Rupnik M, Wilcox MH, Gerding DN.: Clostridium difficile infection: new developments in epidemiology and pathogenesis. In: Nat Rev Microbiol, 2009, 526-536
2006Maja Rupnik, Ingo Just: Large clostridial cytotoxins modifying small GTPases. In: Alouf, J., Popoff, M., The comprehensive sourcebook of bacterial protein toxins. 3rd ed.. Academic Press, 2006. 409-429
2005Maja Rupnik, Stefan Pabst, Marjan Rupnik, Christoph von Eichel-Streiber, Henning Urlaub, Hand-Dieter Soeling Characterization of the cleavage site and function of resulting cleavage fragments after limited proteolysis of Clostridium difficile toxin B (TcdB) by host cells. In: Microbiology , 2005, 199-208