Dr. Keiro Shirotani

Profile

Academic positionAssociate Professor, Senior Lecturer, Reader
Research fieldsGastroenterology,Developmental Biology
KeywordsAlzheimer's Disease, amyloid ß protein, cloning, presenilin, y-secretase

Current contact address

CountryJapan
CityNagasaki-shi
InstitutionNagasaki University
InstituteGraduate School of Biomedical Sciences, Laboratory of Molecular Biology and Biotechnology

Host during sponsorship

Prof. Dr. Dr. h.c. Christian HaassLehrstuhl für Stoffwechselbiochemie, Ludwig-Maximilians-Universität München (LMU), München
Start of initial sponsorship01/07/2002

Program(s)

2001Humboldt Research Fellowship Programme

Publications (partial selection)

2003A. Capell, C. Kaether, D. Edbauer, Keiro Shirotani, S. Merkl, H. Steiner, C. Haass: Nicastrin interacts with gamma-secretase complex components via the N-terminal part of its transmembrane domain. In: J. Biol. Chem., 2003, 52519-52522
2003Keiro Shirotani, D. Edbauer, A. Capell, J. Schmitz, H. Steiner, C. Haass: gamma-secretase activity is associated with a conformational change of nicastrin. In: J. Biol. Chem., 2003, 16474-16477