Dr. Eric Biron

Profile

Academic positionAssociate Professor, Senior Lecturer, Reader
Research fieldsPharmacy,Organic Molecular Chemistry,Natural Product Chemistry
KeywordsAnticancer therapeutics, Bioactive small molecules, Natural bioactive peptides, Peptidomimetics and cyclic peptides, Solid phase synthesis

Current contact address

CountryCanada
CityQuebec
InstitutionUniversite Laval
InstituteFaculte de pharmacie
Homepagewww.pha.ulaval.ca

Host during sponsorship

Prof. Dr. Horst KesslerInstitut für Organische Chemie und Biochemie, Technische Universität München, Garching
Start of initial sponsorship01/09/2003

Publications (partial selection)

2009Horst Kessler, Jayanta Chatterjee, Eric Biron, Lucas Doedens, Florian Opperer, Chaim Gilon,Viktor J. Hruby, Dale Mierke: New perspectives in Peptide Chemistry by N-Alkylation. In: Advances in Experimental Medicine and Biology, 2009, 229-231
2008Eric Biron, Jaynata Chatterjee, Oded Ovadia, Daniel Langenegger, Joseph Brueggen, Daniel Hoyer, Herbert A. Schmid, Raz Jelinek, Chaim Gilon, Ammon Hoffman, Horst Kessler: Improving Oral Bioavailability of Peptides by Multiple N-Methylation: Somatostatin Analogs. In: Angewandte Chemie International Edition, 2008, 2595-2599
2006Horst Kessler, Jayanta Chatterjee, Eric Biron, Viktor J. Vruby, Chaim Gilon, Daniel Hoyer, Dale Mierke: High N-Methylation of Peptides for improvement of Activity and ADME. In: K. Rolka, P. Rekowski, L. Silberring, Peptides 2006, Proceedings of the 29th European Peptide Symposium. Kenes International, 2006. 84-85
2006Eric Biron, Jayanta Chatterjee, Horst Kessler: Optimized selective N-methylation of peptides on solid support. In: Journal of Peptide Science, 2006, 213-219
2005Eric Biron, Horst Kessler: Convenient Synthesis of N-Methylamino Acids Compatible with Fmoc Solid-Phase Peptide Synthesis. In: Journal of Organic Chemistry, 2005, 5183-5189
2005Eric Biron, Jayanta Chatterjee, Horst Kessler: Efficient Synthesis of N-Methyl Amino Acids Compatible with Fmoc Solid-Phase Peptide Synthesis. In: Sylvie E. Blondelle, Understanding Biology Using Peptides, Proceedings of the 19th American Peptide Symposium. American Peptide Society, 2005. 102-103
2005Eric Biron, Daniel Langenegger, Daniel Hoyer, Horst Kessler: Highly N-Methylated Somatostatin Analogues: Synthesis, Biological Activity and Structure-Activity Relationship Studies. . In: Sylvie E. Blondelle, Understanding Biology Using Peptides, Proceedings of the 19th American Peptide Symposium . American Peptide Society, 2005. 423-424
2005Eric Biron, Horst Kessler: Solid-Phase Synthesis of Azole-Based Peptides and Peptidomimetics. In: Sylvie E. Blondelle, Understanding Biology Using Peptides, Proceedings of the 19th American Peptide Symposium. American Peptide Society, 2005. 100-101
2005Martin Sukopp, Richard Schwab, Lucinana Marinelli, Eric Biron, Markus Heller, Edit Varkondi, Akos Pap, Ettore Novellino, Gyorgy Keri, Horst Kessler: Structure-Activity Relationship Studies Optimizing the Antiproliferative Activity of Novel Cyclic Somatostatin Analogues Containing a Restrained Cyclic Beta-Amino Acid. In: Journal of Medicinal Chemistry, 2005, 2916-2926