Dr. Gilles Albert Gasser

Profile

Academic positionLecturer, Assistant Professor, Researcher
Research fieldsInorganic Molecular Chemistry,Biophysical Chemistry
KeywordsBioorganometallic Chemistry, Click Chemistry, Medicinal Inorganic Chemistry, Peptide Nucleic Acids (PNA), Inorganic Chemical Biology

Current contact address

CountryFrance
CityParis
InstitutionParis Sciences & Lettres Research University (PSL)
InstituteChimie Paris Tech - Laboratory for Inorganic Chemical Biology

Host during sponsorship

Prof. Dr. Nils Metzler-NolteLehrstuhl für Anorganische Chemie I, Ruhr-Universität Bochum, Bochum
Start of initial sponsorship01/09/2007

Programme(s)

2007Humboldt Research Fellowship Programme

Publications (partial selection)

2012M. Patra, G. Gasser, M. Wenzel, K. Merz, J.E. Bandow and N. Metzler-Nolte: Metallocene-containing Platensimycin Derivatives: Synthesis and Biological Evaluation. In: Organometallics, 2012, 5760-5771
2012G. Gasser, A. Pinto, S. Neumann, A.M. Sosniak, M. Seitz, K. Merz and N. Metzler-Nolte: Synthesis, Characterisation and Bioimaging of a New Fluorescent Rhenium-Containing PNA Bioconjugate. In: Dalton Trans. , 2012, 2304-2313
2011G. Gasser and N. Metzler-Nolte: Metal Compounds as Enzyme Inhibitors. In: E. Alessio, Bioinorganic Medicinal Chemistry. Wiley-VCH, 2011. 351-382
2011G. Gasser, I. Ott, N. Metzler-Nolte: Organometallic Anticancer Compounds. In: J. Med. Chem., 2011, 3-25
2011G. Gasser, S. Neumann, I. Ott, M. Seitz, R. Heumann and N. Metzler-Nolte: Preparation and Biological Evaluation of Di-Hetero Organometallic-Containing PNA Bioconjugates. In: Eur. J. Inorg. Chem. , 2011, 5471-5478
2011M. Patra, G. Gasser, M. Wenzel, K. Merz, J.E. Bandow and N. Metzler-Nolte: Synthesis of Optically Active Ferrocene-Containing Platensimycin Derivatives with a C6–C7 Substitution Pattern. In: Eur. J. Inorg. Chem., 2011, 3295-3302
2011G. Gasser, A.M. Sosniak, A. Leonidova, H. Braband and N. Metzler-Nolte: Towards the Preparation of novel Re/99mTc Tricarbonyl-Containing Peptide Nucleic Acid Bioconjugates. In: Aust. J. Chem., 2011, 265-272
2010G. Gasser, K. Jäger, M. Zenker, R. Bergmann, J. Steinbach, H. Stephan and N. Metzler-Nolte: Preparation, 99mTc-Labeling and Biodistribution Studies of a PNA Oligomer Containing a New Ligand Derivative of 2,2’-Dipicolylamine . In: J. Inorg. Biochem., 2010, 1133-1140
2010M. Patra, G. Gasser, D. Bobukhov, K. Merz, A.V. Shtemenko and N. Metzler-Nolte: Sequential Insertion of three Different Organometallics into a Versatile Building Block Containing a PNA Backbone. In: Dalton Trans., 2010, 5617-5619
2010M. Patra, G. Gasser, M. Wenzel, K. Merz, J.E. Bandow and N. Metzler-Nolte: Synthesis and Biological Evaluation of Ferrocene-containing Bioorganometallics Inspired by the Antibiotic Platensimycin Lead Structure. In: Organometallics, 2010, 4312-4319
2009M. Patra, G. Gasser, K. Merz, I. Ott, J.E. Bandow and N. Metzler-Nolte: Synthesis and Biological Evaluation of Chromium Bioorganometallics Based on the Antibiotic Platensimycin Lead Structure . In: ChemMedChem, 2009, 1930-1938
2009Gilles Gasser, Merja A. Neukamm, Alexandra Ewers, Oliver Brosch, Thomas Weyhermüller and Nils Metzler-Nolte: Synthesis and Characterisation of Dicobalthexacarbonyl-Alkyne Amino Acid, Peptide and PNA Monomer Derivatives. In: Inorg. Chem., 2009, 3157-3166
2009Gilles Gasser, Oliver Brosch, Alexandra Ewers, Thomas Weyhermüller and Nils Metzler-Nolte: Synthesis and Characterisation of Hetero-Bimetallic Organometallic Phenylalanine and PNA Monomer Derivatives. In: Dalton Trans., 2009, 4310-4317
2009A. Sosniak, G. Gasser and N. Metzler-Nolte: Thermal Melting Studies of Alkyne and Ferrocene-containing PNA Bioconjugates . In: Org. Biomol. Chem. , 2009, 4992-5000
2009N. Hüsken, G. Gasser, S.D. Köster and N. Metzler-Nolte “Four-Potential” Ferrocene Labelling of PNA Oligomers via Click Chemistry. In: Bioconjugate Chem., 2009, 1578-1586
2008David S. Köster, Jan Diettrich, Gilles Gasser, Nina Hüsken, Isabel C. Henao Castañeda, Jorge L. Jios, Carlos O. Della Védova, Nils Metzler-Nolte : Spectroscopic and Electrochemical Studies of Ferrocenyl Triazole Amino Acid and Peptide Bioconjugates synthesized by Click Chemistry . In: Organometallics, 2008, 6326-6332
2008Gilles Gasser, Nina Hüsken, S. David Köster and Nils Metzler-Nolte: Synthesis of organometallic PNA oligomers by click chemistry. In: Chem. Comm., 2008, 3675-3677