Dr. Sreekumar Vellalath

Profile

Academic positionPost Doc
Research fieldsOrganic Molecular Chemistry
Keywordspipoxolan, acetalization, cevimeline hydrochloride

Current contact address

Host during sponsorship

Prof. Dr. Dr. h.c. Benjamin ListMax-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr
Prof. Dr. Dr. h.c. Benjamin ListAbteilung Homogene Katalyse, Max-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr
Start of initial sponsorship01/03/2008

Programme(s)

2007Humboldt Research Fellowship Programme

Publications (partial selection)

2010Coric, I.; Vellalath, S.; List, B.: Catalytic Asymmetric Transacetalization. . In: J. Am. Chem. Soc., 2010, 8536-8537
2010Vellalath, S.; Coric, I.; List, B: N-Phosphinyl Phosphoramide - A Chiral Brønsted Acid Motif for the Direct Asymmetric N,O-Acetalization of Aldehydes. . In: Angew. Chem., Int. Ed., 2010, 9749-9752
2010Nair, V.; Vellalath, S.; Babu, B. P.; Varghese, V.; Paul, R. R.; Suresh, E.: NHC-catalysed Annulation of Enals to tethered Dienones: Efficient Synthesis of Bicyclic Dienes.. In: Org. Biomol. Chem., 2010, 4861-4866
2009Nair, V.; Babu, B. P.; Vellalath, S.; Varghese, V.; Raveendran, A. E.; Suresh, E.: Nucleophilic Heterocyclic Carbene Catalyzed Annulation of Enals to Chalcones in Methanol.: A Stereoselective Synthesis of Highly Functionalized Cyclopentanes.. In: Org. Lett., 2009, 2507-2510
2008Nair, V.; Mathew, S. C.; Vellalath, S.; Pillai, A. N.; Suresh, E.: An Efficient Three-Component Reaction Involving Triazolylidene Carbene, DMAD, and Aldehydes for the Synthesis of Furanone Derivatives.. In: Synthesis, 2008, 551-555
2008Cheng, X.; Vellalath, S.; Goddard, R.; List, B.: Direct Catalytic Asymmetric Synthesis of Cyclic Aminals from Aldehydes.. In: J. Am. Chem. Soc., 2008, 15786-15787
2008Nair, V.; Vellalath, S.; Babu, B. P.: Recent Advances in Carbon-Carbon Bond-Forming Reactions Involving Homoenolates Generated by NHC catalysis.. In: Chem. Soc. Rev., 2008, 2691-2698
2008Nair, V.; Babu, B. P.; Vellalath, S.; Suresh, E.: Stereoselective Synthesis of Spirocyclopentanones via N-heterocyclic Carbene-Catalyzed Reactions of Enals and Dienones.. In: Chem. Commun., 2008, 747-749
2007Nair, V.; Vellalath, S.; Poonoth, M.; Suresh, E.; Viji, S.: N-Heterocyclic Carbene Catalyzed Reaction of Enals and Acyclic-1,2-diones via Homoenolate: Synthesis of 4,5,5-Trisubstituted -Butyrolactones.. In: Synthesis , 2007, 3195-3200
2006Nair, V.; Menon, R. S. ; Vellalath, S.: Asymmetric Synthesis of Quinine: A Landmark in Organic Synthesis.. In: Natural Product Communications, 2006, 899
2006Nair, V.; Vellalath, S.; Poonoth, M.; Suresh, E.: N-Heterocyclic Carbene Catalyzed Reaction of Chalcones and Enals via Homoenolate: an Efficient Synthesis of 1,3,4-Trisubstituted Cyclopentenes.. In: J. Am. Chem. Soc, 2006, 8736-8737
2006Nair, V.; Vellalath, S.; Poonoth, M.; Mohan, R.; Suresh, E.: N-Heterocyclic Carbene Catalyzed Reaction of Enals and 1,2-Dicarbonyl Compounds: Stereoselective Synthesis of Spiro -Butyrolactones.. In: Org. Lett., 2006, 507-509
2006Nair, V.; Poonoth, M.; Vellalath, S.; Suresh, E.; Thirumalai, R.: N-Heterocyclic Carbene Catalyzed [8+3] Annulation of Tropone via Homoenolate.. In: J. Org. Chem., 2006, 8964
2006 Nair, V.; Deepthi, A.; Poonoth, M.; Santhamma, B.; Vellalath, S.; Babu, B. P.; Mohan, R.; Suresh, E.: Reaction of Dimethoxycarbene-DMAD Zwitterion with 1,2-Diones and Anhydrides: A Novel Synthesis of Highly Substituted Dihydrofurans and Spirodihydrofurans.. In: J. Org. Chem., 2006, 2313-2319
2005Nair, V.; Menon, R. S. ; Sreekumar, V. Multicomponent Reactions Based on Nucleophilic Carbenes and their Applications in Organic Synthesis.. In: Pure. Appl. Chem., 2005, 1191-1198
2005Nair, V.; Beneesh, P. B.; Sreekumar, V.; Bindu, S.; Menon, R. S.; Deepthi, A.: The Multicomponent Reaction of Dimethoxycarbene, Dimethyl Butynedioate and Electrophilic Styrenes: An Unprecedented Synthesis of Highly Substituted Cyclopentanone Acetals.. In: Tetrahedron Lett., 2005, 201-203
2005Nair, V.; Sreekumar, V. ; Bindu, S.; Suresh, E.: Two Unprecedented Multicomponent Reactions Involving N-Heterocyclic Carbenes, Activated Acetylenes and Aldehydes.. In: Org. Lett., 2005, 2297-2300
2004Nair, V.; Menon, R. S.; Beneesh, P. B.; Sreekumar, V.; Bindu, S.: A Novel Multicomponent Reaction Involving Isocyanide, Dimethyl Acetylenedicarboxylate (DMAD), and Electrophilic Styrenes: Facile Synthesis of Highly Substituted Cyclopentadienes.. In: Org. Lett., 2004, 767-769
2004Nair, V.; Bindu, S.; Sreekumar, V. N-Heterocyclic Carbenes: Reagents, Not Just Ligands!.. In: Angew. Chem., Int. Ed., 2004, 5130-5135
2003Nair, V.; Bindu, S.; Sreekumar, V.; Balagopal, L.: Novel Dipolar Cycloaddition Reactions of Zwitterionic Species Generated from Dimethoxycarbene and Dimethyl Acetylenedicarboxylate with Carbonyl Compounds: Facile Synthesis of Dihydrofuran Derivatives.. In: Synthesis , 2003, 1446-1456
2003Nair, V.; Bindu, S.; Sreekumar, V.; Rath, N. P.: Unprecedented Reactivity of N-Heterocyclic Carbenes toward DMAD and Aldehydes Leading to Novel Multicomponent Reactions.. In: Org. Lett., 2003, 665-667
2002Nair, V.; Bindu, S.; Sreekumar, V.; Chiaroni, A.: A Novel Approach to the Synthesis of Bicyclic Lactones via an Interrupted Nazarov Reaction of gem-divinyl Dihydrofurans.. In: Org. Lett., 2002, 2821-2823
2002Bahulayan, D.; Narayan, G.; Sreekumar, V.; Lalithambika, M.: Natural Bentonite Clay/Dilute HNO3 (40%) - A Mild, Efficient and Reusable Catalyst/Reagent System for selective mono Nitration and Benzylic Oxidations.. In: Synth. Commun., 2002, 3565-3574