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Profile
| Academic position | Associate Professor, Senior Lecturer, Reader |
|---|---|
| Research fields | Biochemistry,Biophysical Chemistry |
| Keywords | Structure of oligomers and amyloid fibrils, Viral Structure, P2X7 receptor, Structure-based vaccine design, Solid-State NMR |
| Honours and awards | 2023: Honourable mention, XII Semana de Integração Acadêmica, UFRJ 2017: Ambassador Scientist from Alexander von Humboldt Foudation in Brazil, Alexander von Humboldt Foundation 2014: Ambassador Scientist from Alexander von Humboldt Foudation in Brazil, Alexander von Humboldt Foundation 2013: Roberto Alcântara Gomes Prize, Federação de Sociedades de Biologia Experimental (FeSBE). 2011: Programa de Apoio a Docente Recém-Doutor Antonio Luís Vianna, Universidade Federal do Rio de Janeiro. 2008: Georg Forster Research Fellowships for Postdoctoral Researcher, Alexander von Hunboldt Stiftung. 2007 2007: Honorable mention, XXIX Jornada Juilio Massarani de Iniciacao Cientifica, Artistica e Cultural da UFRJ. 2007: Honourable mention, XXII Reunião Anual da Federação de Sociedades de Biologia Experimental FeSBE. 2005: VI Painel Prize, XXXIV, Sociedade Brasileira de Bioquímica e Biologia Molecular. SBV 2003: IV Painel Prize, XXXII Reunião Anual da Sociedade Brasileira de Bioquímica e Biologia Molecular- SBBq 2002: VI Helio Gelli Pereira Prize, XIII National Meeting of Virology, SBV |
Current contact address
| Country | Brazil |
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| City | Rio de Janeiro |
| Institution | Universidade Federal do Rio de Janeiro (UFRJ) |
| Institute | Instituto de Bioquimica Medica |
Host during sponsorship
| Prof. Dr. Hartmut Oschkinat | Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin |
|---|---|
| Prof. Dr. Hartmut Oschkinat | Arbeitsguppe In-Cell NMR, Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin |
| Prof. Dr. Monica Santos de Freitas | Instituto de Bioquimica Medica, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro |
| Start of initial sponsorship | 01/11/2008 |
Programme(s)
| 2008 | Georg Forster Research Fellowship Programme for Postdocs |
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Publications (partial selection)
| 2018 | Mônica Santos de Freitas, Raheleh Rezaei Araghi, Enrico Brandenburg, Jork Leitererd, Franziska Emmerling, Kristin Folmert, Ulla I.M.Gerling-Driessen, Benjamin Bardiaux, Christoph Böttcher, Kevin Pagel, Anne Diehl, Hans v.Berlepsch, Hartmut Oschkinat, Beate Koksch: The protofilament architecture of a de novo designed coiled coil-based amyloidogenic peptide. In: Journal of Structural Biology, 2018, |
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| 2013 | Fernanda Luna da Silva, Eduardo Coelho Cerqueira, Mônica Santos de Freitas, Daniela Leão Gonçalves, Lilian Terezinha Costa, Cristian Follmer: Vitamins K interact with N-terminus α-synuclein and modulate the protein fibrillization in vitro. Exploring the interaction between quinones and α-synuclein. In: Neurochemistry International, 2013, 103-112 |
| 2011 | Mônica S. Freitas,Cristian Follmer, Lilian T. Costa, Cecília Vilani, M. Lucia Bianconi, Carlos Alberto Achete, and Jerson L. Silva: Measuring the strength of interaction between the Ebola fusion peptide and lipid rafts: implications for membrane fusion and virus infection.. In: Plos ONE, 2011, e15756 |
| 2011 | Carolina A. Braga, Cristian Follmer, Fernando L. Palhano, Elias Khattar, Mônica S. Freitas, Luciana Romão, Saviana Di Giovanni, Hilal A. Lashuel, Jerson L. Silva, Debora Foguel: The anti-Parkinsonian drug selegiline delays the nucleation phase of α-synuclein aggregation leading to the formation of nontoxic species.. In: J Mol Biol, 2011, 254-273 |
| 2010 | Jerson Lima da Silva Tuane Cristina Vieira Mariana Pierre Gomes Ana Paula DInis Ano Bom Luiz Mauricio Trombaioli Monica Santos de Freitas Daniela Ishimaru Yraima Cordeiro Debora Foguel: Ligand Binding and Hydration in Protein Misfolding: Insights from Studies of Prion and p53 Tumor Suppressor Proteins (dagger).. In: Accounts Chemical Research, 2010, 271-279 |
| 2010 | Guilherme A.P. Oliveira Elaine S. Costa Mônica S. Freitas Fabianno F. Dutra Simone F. Maia Maria C. Guerra Maria D.Tabernero Radovan Borojevic Ivone B. Otazu Jerson L. Silva: Positive Response to Therapy with Imatinib Mesylate in Childhood Chronic Myeloid Leukaemia. In: Brazilian Journal of Medical and Biological Research, 2010, --- |
| 2010 | Ana Paula Dinis Ano Bom Monica Santos de Freitas Flavia S Moreira Danielly Ferraz Daniel Sanches Andre M O Gomes Ana Paula Valente Yraima Cordeiro Jerson Lima da Silva : The p53 Core Domain is a Molten Globule at Low pH: Functional Implications of a Partially Unfolded Structure. In: The Journal Biological Chemistry, 2010, 2857-2866 |
| 2009 | Pedro R. Barros Hubert Stassen Mônica Santos de Freitas Célia R. Carlini Marco A. C. Nascimento Cristian Follmer: Membrane-disruptive properties of the bioinsecticide Jaburetox-2Ec: Implications to the mechanism of the action of insecticidal peptides derived from ureases.. In: Biochimica et Biophysica Acta, 2009, 1848-1854 |
| 2009 | Pedro Celso Nogueira Teixeira Cristina Alves Magalhães de Souza Mônica Santos de Freitas Debora Foguel Ernesto Raul Caffarena Luiz Anastacio Alves: Predictions suggesting a participation of beta-sheet configuration in the M2 domain of the P2X(7) receptor: a novel conformation?. In: Biophysical Journal, 2009, 951-963 |
| 2007 | Monica Santos de Freitas Luciane Pinto Gaspar Marcos Lorenzoni Fabio C L Almeida Luzineide W Tinoco Marcius S Almeida Lenize F Maia Leo Degreve Ana Paula Valente Jerson Lima da Silva: Structure of the Ebola fusion peptide in a membrane-mimetic environment and the interaction with lipid rafts.. In: The Journal of Biological Chemistry, 2007, 27306-27314 |
| 2006 | Lenize F Maia Marcia S Soares Ana P Valente Fabio C L Almeida Andrea C Oliveira Andre M O Gomes Monica Santos de Freitas Anette Schneemann John Johnson Jerson Lima da Silva: Structure of a membrane-binding domain from a non-enveloped animal virus: insights into the mechanism of membrane permeability and cellular entry.. 2006, 29278-29286 |
| 2006 | Mônica Santos de Freitas Andrea T Da Poian Ortrud M Barth Moacyr A Rebello Jerson Lima da Silva Luciane Pinto Gaspar: The fusogenic state of Mayaro virus induced by low pH and by hydrostatic pressure.. In: Cell Biochemistry and Biophysics, 2006, 325-335 |
| 2002 | Luciane P Gaspar Ana C B Silva Andre M O Gomes Monica Santos de Freitas Ana P D Ano Bom Waleska D Schwarcz Jiri Mestecky Miroslav J Novak Debora Foguel Jerson Lima da Silva: Hydrostatic pressure induces the fusion-active state of enveloped viruses.. In: The Journal of Biological Chemistry, 2002, 8433-8439 |