Publications (partial selection)
2013 | Sandrine Marchais-Oberwinkler,Kuiying Xu, Marie Wetzel, Enrico Perspicace, Matthias Negri, Arne Meyer, Alex Odermatt, Gabriele Möller, Jerzy Adamski, Rolf W. Hartmann: Structural Optimization of 2,5-Thiophene Amides as Highly Potent and Selective 17β-Hydroxysteroid Dehydrogenase Type 2 Inhibitors for the Treatment of Osteoporosis. In: J, Med. Chem., 2013, 167-181 |
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2011 | Sandrine Marchais-Oberwinkler, Claudia Henn, Gabriele Möller, Tobias Klein, Matthias Negri, Alexander Oster, Alessandro Spadaro, Ruth Werth, Marie Wetzel, Kuiying Xu, Martin Frotscher, Rolf W. Hartmann, Jerzy Adamski: 17β-Hydroxysteroid dehydrogenases (17β-HSDs) as therapeutic targets: protein structures, functions, and recent progress in inhibitor development . In: J. steroid biochem. Mol. biol., 2011, 66-82 |
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2011 | Kuiying Xu, Marie Wetzel, Rolf W. Hartmann, Sandrine Marchais-Oberwinkler: Synthesis and Biological Evaluation of Spiro-d-lactones as Inhibitors of 17 β -Hydroxysteroid Dehydrogenase Type 2 (17 β -HSD2). In: Lett. Drug Design Disc, 2011, 406-421 |
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2011 | Kuiying Xu, Yaseen A. Al-Soud, Marie Wetzel, Rolf W. Hartmann, Sandrine Marchais-Oberwinkle: Triazole ring-opening leads to the discovery of potent nonsteroidal 17β-hydroxysteroid dehydrogenase type 2 inhibitors. In: Eur. J. Med. Chem. , 2011, 5978-5990 |
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