DEEN
Magazine Humboldt Kosmos Newsroom Newsletter

Search

Awards and fellowships Search Humboldtians

Search for tags

Prof. Dr. Kerstin Kaufmann

Profile

Academic positionFull Professor
Research fieldsPlant Biochemistry and Biophysics,Plant Genetics and Genomics
KeywordsPlant transcriptional regulation, Floral homeotic proteins, Flower development, MADS-box transcription factors

Current contact address

CountryGermany
CityBerlin
InstitutionHumboldt-Universität zu Berlin
InstituteArbeitsgruppe Pflanzliche Zell- und Molekularbiologie

Host during sponsorship

Prof. Dr. Bernd Müller-RöberInstitut für Biochemie und Biologie, Universität Potsdam, Golm
Prof. Dr.-Ing. Sabine KunstHumboldt-Universität zu Berlin, Berlin
Start of initial sponsorship01/12/2012

Programme(s)

2012Sofja Kovalevskaja Award Programme

Nominator's project description

The development of flowers is one of the best understood and economically most important developmental processes in plants. Flower formation relies on the coordinated action of regulatory proteins, so-called transcription factors; these proteins control the spatial and time-dependent activity of myriads of other genes present in the organism. The goal of Dr. Kaufmann´s research is to unravel how one family of such master regulators (namely the MADS-box factors) coordinate cellular differentiation to generate specific floral organ morphologies. While her previous ground-breaking work focused on the model plant Arabidopsis thaliana (thale cress), Dr. Kaufmann will now extend her studies to two other, closely related plant species, using a combination of cutting-edge genomics- and proteomics-based techniques, in conjunction with biocomputational data analysis. This research will reveal the degree of evolutionary conservation of floral master regulators and how the diversification of their target genes may have contributed to the morphological variation we see in the flowering part of our world.

Publications (partial selection)

2019Dijun Chen, Wenhao Yan, Julia Schumacher, Diego Durantini, Julia Engelhorn, Ming Chen, Cristel Carles, Kerstin Kaufmann: Dynamic control of enhancer activity drives stage-specific gene expression during flower morphogenesis. In: Nature Communications, 2019,
2018Yongjing Liu, Liangyu Fu, Kerstin Kaufmann, Dijun Chen, Ming Chen: A practical guide for DNase-seq data analysis: from data management to common applications.. In: Brief Bioinf, 2018,
2018Dijun Chen, Wenhao Yan, Liang-Yu Fu, Kerstin Kaufmann Architecture of gene regulatory networks controlling flower development in Arabidopsis thaliana.. In: Nature Communications, 2018, 4534
2018Wenhao Yan, Dijun Chen, Cezary Smaczniak, Julia Engelhorn, Haiyang Liu, Wenjing Yang, Alexander Graf, Cristel C. Carles, Dao-Xiu Zhou, Kerstin Kaufmann Dynamic and spatial restriction of Polycomb activity by plant histone demethylases.. In: Nature Plants, 2018, 681-689
2018Kerstin Kaufmann, Chiara A Airoldi: Master regulatory transcription factors in plant development: A blooming perspective. In: Chromatin; Floral transition; Flower development; Gene-regulatory networks; Master regulators; Plant transcription factors, Plant Transcription Factors: Methods and Protocols (Methods in Molecular Biology) . Humana Press, 2018. 3-33
2018Suzanne de Bruijn, Tao Zhao, Jose M. Muiño, Eric M. Schranz, Gerco C. Angenent, Kerstin Kaufmann: PISTILLATA paralogs in Tarenaya hassleriana have diverged in interaction specificity. In: BMC Plant Biology, 2018, 368
2017Neha Sharma, Philip Ruelens, Mariëlla D'hauw, Thomas Maggen, Niklas Dochy, Sanne Torfs, Kerstin Kaufmann, Antje Rohde, Koen Geuten: An FLC homolog is a vernalization-regulated repressor in Brachypodium and is cold-regulated in wheat. In: Plant Physiology, 2017, 1301-1305
2017Kerstin Kaufmann, Dijun Chen: From genes to networks: characterizing gene-regulatory interactions in plants. In: Kerstin Kaufmann, Bernd Mueller-Roeber, Plant Gene Regulatory Networks: Methods and Protocols (Methods in Molecular Biology, Band 1629). Humana Press, 2017. 1-11
2017Dijun Chen, Kerstin Kaufmann: Integration of genome-wide TF binding and gene expression data to characterize gene regulatory networks in plant development.. In: Kerstin Kaufmann, Bernd Mueller-Roeber, Plant Gene Regulatory Networks: Methods and Protocols (Methods in Molecular Biology, Band 1629). Humana Press, 2017. 239-269
2017Kerstin Kaufmann, Bernd Mueller Roeber (Editors): Plant Gene Regulatory Networks: Methods and Protocols (Methods in Molecular Biology, Band 1629). Humana Press, 2017
2017Cezary Smaczniak, Gerco C Angenent, Kerstin Kaufmann: SELEX-seq – a method to determine DNA-binding specificities of plant transcription factors.. In: Kerstin Kaufmann, Bernd Mueller-Roeber, Plant Gene Regulatory Networks: Methods and Protocols (Methods in Molecular Biology, Band 1629). Humana Press, 2017. 67-82
2017Philip Ruelens, Zhicheng Zhang, Hilda van Mourik, Steven Maere, Kerstin Kaufmann, Koen Geuten: The origin of floral organ identity quartets.. In: The Plant Cell, 2017, 229-242
2016Wenhao Yan, Dijun Chen, Kerstin Kaufmann: Efficient multiplex mutagenesis by RNA-guided Cas9 and its use in the characterization of regulatory elements in the AGAMOUS gene.. In: Plant Methods, 2016, 23
2016Jose M. Muiño, Suzanne de Bruijn, Alice Pajoro, Koen Geuten, Martin Vingron, Gerco C. Angenent, Kerstin Kaufmann: Evolution of DNA-binding sites of a floral master regulatory transcription factor.. In: Molecular Biology and Evolution, 2016, 185-200
2016Christopher R Wils, Kerstin Kaufmann: Gene-regulatory networks controlling inflorescence and flower development in Arabidopsis thaliana.. In: Biochim Biophys Acta, 2016, 95-105
2016Wenhao Yan, Dijun Chen, Kerstin Kaufmann: Molecular mechanisms of floral organ specification by MADS domain proteins.. In: Current Opinion in Plant Biology, 2016, 154-162
2013Philip Ruelens, Ruud A. de Maagd, Sebastian Proost, Günter Theißen, Koen Geuten, Kerstin Kaufmann: FLOWERING LOCUS C in monocots and the tandem origin of angiosperm-specific MADS-box gene subfamilies.. In: Nature Communications, 2013, 2280
2013Shifeng Cheng, Erik van den Bergh, Peng Zeng, Xiao Zhong, Jiajia Xu, Xin Liu, Johannes Hofberger, Suzanne de Bruijn, Amey S. Bhide, Canan Kuelahoglu, Chao Bian, Jing Chen, Guangyi Fan, Kerstin Kaufmann, Jocelyn C. Hall, Annette Becker, Andrea Bräutigam, Andreas P.M. Weber, Chengcheng Shi, Zhijun Zheng, Wujiao Li, Mingju Lv, Yimin Tao, Junyi Wang, Hongfeng Zou, Zhiwu Quan, Julian M. Hibberd, Gengyun Zhang, Xin-Guang Zhu, Xun Xu, M. Eric Schranz: The genome of Tarenaya hassleriana provides insights into reproductive trait and genome evolution of crucifers.. In: The Plant Cell, 2013, 2813-2830
Dijun Chen, Liang-Yu Fu, Dahui Hu, Christian Klukas, Ming Chen, Kerstin Kaufmann The HTPmod Shiny application enables modeling and visualization of large-scale biological data.. In: Communications Biology, , 89