Prof. Dr. Allan Patrick Macabeo

Profile

Academic positionFull Professor
Research fieldsNatural Product Chemistry,Organic Molecular Chemistry
KeywordsSynthetic methodology, Natural products chemistry, Medicinal chemistry, Asymmetric synthesis and catalysis, Drug discovery and development
Honours and awards

2017: University of Santo Tomas Dangal Hall of Fame Award

2015: Outstanding Young Scientist of the Philippines in the Field of Organic Chemistry

2015: The World Academy of Sciences (TWAS) Award in Organic Chemistry

2014: ASEAN Young Scientist and Technologist Award (First Runner-Up)

2013: Merck Young Scientist Award in the Chemical Sciences

2013: National Academy of Science and Technology Talent Search for Young Scientists Awardee

Current contact address

CountryPhilippines
CityManila
InstitutionUniversity of Santo Tomas
InstituteCollege of Science, Department of Chemistry

Host during sponsorship

Prof. Dr. Marc StadlerAbteilung Mikrobielle Wirkstoffe, Helmholtz-Zentrum für Infektionsforschung GmbH, Braunschweig
Prof. Dr. Allan Patrick MacabeoCollege of Science, Department of Chemistry, University of Santo Tomas, Manila
Start of initial sponsorship01/05/2017

Programme(s)

2016Georg Forster Research Fellowship Programme for Postdocs

Publications (partial selection)

2024Franklin V. Ibana, Von Novi O. de Leon, Joe Anthony H. Manzano, Agnes L. Castillo, Allan Patrick G. Macabeo: Alkenylated Phenolics from Syzygium lineatum with Antiproliferative Activity against Chronic Myeloid Leukemia Cells. In: Journal of Applied Pharmaceutical Science, 14, 2024, 1-7
2024Joe Anthony H. Manzano, Lloyd Christian J. Llames, Allan Patrick G. Macabeo: Tetrahydrobisbenzylisoquinoline alkaloids from Phaeanthus ophthalmicus inhibit target enzymes associated with type 2 diabetes and obesity. In: Journal of Applied Pharmaceutical Science, 14, 2024, 230-237
2023Nur Shahidah Sharoman, Gabriel Luis L. Neri, Najmah P. S. Hasan, Allan Patrick G. Macabeo, Mohd Tajudin Mohd Ali: A Streamlined Asymmetric Synthesis of Substituted Geissman-Waiss Lactones, Oseltamivir Precursors and Peptidyl Hydroxylactams from (–)-Azidocyclohexenol. In: Acta Manilana, 71, 2023, 110-118
2023Katherine Yasmin M. Garcia, Joe Anthony H. Manzano, Allan Patrick G. Macabeo: An α-Glucosidase and Pancreatic Lipase Inhibitory Cytochalasan Derivative from the Dothideomycetes fungus, Sparticola triseptata. In: Acta Manilana, 71, 2023, 97-109
2023Kin Israel R Notarte, Mark Tristan J Quimque, Imee T Macaranas, Abbas Khan, Adriel M Pastrana, Oliver B Villaflores, Hans Christian P Arturo, Delfin Yñigo H Pilapil IV, Sophia Morgan M Tan, Dong-Qing Wei, Arlette Wenzel-Storjohann, Deniz Tasdemir, Chia-Hung Yen, Seon Yeong Ji, Gi-Young Kim, Yung Hyun Choi, Allan Patrick G Macabeo: Attenuation of Lipopolysaccharide-Induced Inflammatory Responses through Inhibition of the NF-κB Pathway and the Increased NRF2 Level by a Flavonol-Enriched n-Butanol Fraction from Uvaria alba. In: ACS Omega, 8, 2023, 5377–5392
2023Joe Anthony H Manzano, Marlan T Magdalaga, Ellha Mae Nicole M Nicolas, Milen Angelie R Medalla, Miguel Gabriel Z Urrutia, Lloyd Christian J Llames, Allan Patrick G Macabeo, Rey Donne S Papa: First Record of Culturable Microbial Communities Associated with the Freshwater Sponge Spongilla alba in Lake Taal, Philippines.. In: Philippine Journal of Science, 152, 2023, 501-514
2023Mark Tristan J Quimque, Adrian D Go, Justin Allen K Lim, Warren S Vidar, Allan Patrick G Macabeo: Mycobacterium tuberculosis Inhibitors Based on Arylated Quinoline Carboxylic Acid Backbones with Anti-Mtb Gyrase Activity. In: International Journal of Molecular Sciences, 24, 2023, 11632
2023Mark Tristan Quimque, Kin Israel Notarte, Xela Amor Adviento, Mikhail Harvey Cabunoc, Von Novi de Leon, Felippe Steven Louis Delos Reyes, Eiron John Lugtu, Joe Anthony Manzano, Sofia Nicole Monton, John Emmanuel Muñoz, Katherine Denise Ong, Delfin Ynigo Pilapil IV, Sophia Morgan Tan, Justin Allen Lim, Allan Patrick Macabeo: Polyphenolic Natural Products Active In Silico against SARS-CoV-2 Spike Receptor Binding Domains and Non-Structural Proteins-A Review.. In: Combinatorial Chemistry & High Throughput Screening, 26, 2023, 459-488
2022Katherine Yasmin M Garcia, Mark Tristan J Quimque, Christopher Lambert, Katharina Schmidt, Gian Primahana, Theresia EB Stradal, Andreas Ratzenböck, Hans-Martin Dahse, Chayanard Phukhamsakda, Marc Stadler, Frank Surup, Allan Patrick G Macabeo: Antiproliferative and Cytotoxic Cytochalasins from Sparticola triseptata Inhibit Actin Polymerization and Aggregation. In: Journal of Fungi, 8, 2022, 560
2022Ivane N Malaluan, Joe Anthony H Manzano, John Emmanuel R Muñoz, Timothy John L Bautista, Hans-Martin Dahse, Mark Tristan J Quimque, Allan Patrick G Macabeo: Antituberculosis and Antiproliferative Activities of the Extracts and Tetrahydrobisbenzylisoquinoline Alkaloids from Phaeanthus ophthalmicus: In Vitro and In Silico Investigations. In: Philippine Journal of Science, 151, 2022, 371-381
2022Mark Tristan J Quimque, Kin Israel R Notarte, Von Novi O de Leon, Joe Anthony H Manzano, John Emmanuel R Muñoz, Delfin Yñigo H Pilapil IV, Justin Allen K Lim, Allan Patrick G Macabeo: Computationally Repurposed Natural Products Targeting SARS-CoV-2 Attachment and Entry Mechanisms. In: Frontiers of COVID-19: Scientific and Clinical Aspects of the Novel Coronavirus 2019, 2022, 505-537
2022Joe Anthony H Manzano, Cecil Laurence M Cruz III, Mark Tristan J Quimque, Allan Patrick G Macabeo: In Silico Potentials of Alpinia galanga Constituents against Human Placental Aromatase Vital in Postmenopausal Estrogen-dependent Breast Cancer Pathogenesis. In: Philippine Journal of Science, 151, 2022, 2101-2115
2022Jeremiah Gabriel G Africa, Hans Christian P Arturo, Lorie Jean M Bernardo, James Kyle Anthony R Ching, Olivia Casandra E de la Cruz, Jenina Beatriz E Hernandez, Ryan Joseph Y Magsipoc, Cale Twaine C Sales, Jay Carl M Agbay, Gabriel Luis L Neri, Mark Tristan J Quimque, Allan Patrick G. Macabeo: In Silico Triple Targeting of SARS-CoV-2 3CLpro, PLpro, and RdRp by Philippine Antitubercular Natural Products Libraries. In: Philippine Journal of Science, 151, 2022, 35-58
2022Rey Arturo Fernandez, Mark Tristan Quimque, Kin Israel Notarte, Joe Anthony Manzano, Delfin Yñigo Pilapil IV, Von Novi de Leon, John Jeric San Jose, Omar Villalobos, Nisha Harur Muralidharan, M Michael Gromiha, Simone Brogi, Allan Patrick G Macabeo: Myxobacterial depsipeptide chondramides interrupt SARS-CoV-2 entry by targeting its broad, cell tropic spike protein. In: Journal of Biomolecular Structure and Dynamics, 22, 2022, 12209-12220
2022Mark Tristan J Quimque, Ryan Joseph Y Magsipoc, Lloyd Christian J Llames, Angeli Izza G Flores, Katherine Yasmin M Garcia, Andreas Ratzenböck, Hidayat Hussain, Allan Patrick G Macabeo: Polyoxygenated Cyclohexenes from Uvaria grandiflora with Multi-Enzyme Targeting Properties Relevant in Type 2 Diabetes and Obesity. In: ACS Omega, 7, 2022, 36856-36864
2022Viktor Aloysius A. Fellizar, Aaron Cyrus A. Concepcion, Emmanuel Louise A. Furaque, Angela Maxine G. Fabian, Von Novi O. de Leon, Delfin Yñigo Pilapil IV, Mark Tristan J. Quimque, Notarte, Allan Patrick G. Macabeo: Virtual Screening of Cyanobacterial Metabolites as Inhibitors of SARS-CoV-2 Host Cell Entry, Viral Replication, and Host Immunity Modulation Infective Mechanisms. In: Philippine Journal of Science, 151, 2022, 2385–2416
2022Simone Brogi, Mark Tristan Quimque, Kin Israel Notarte, Jeremiah Gabriel Africa, Jenina Beatriz Hernandez, Sophia Morgan Tan, Vincenzo Calderone, Allan Patrick Macabeo: Virtual combinatorial library screening of quinadoline B derivatives against SARS-CoV-2 RNA-dependent RNA polymerase. In: Computation, 10, 2022, 7
2022Ma Sheila M de Jesus, Allan Patrick G Macabeo, John Donnie A Ramos, Von Novi O de Leon, Kaori Asamitsu, Takashi Okamoto: Voacanga globosa Spirobisindole Alkaloids Exert Antiviral Activity in HIV Latently Infected Cell Lines by Targeting the NF-kB Cascade: In Vitro and In Silico Investigations. In: Molecules, 27, 2022, 1078
2021Ferry Saputra, Yu-Heng Lai, Rey Arturo T Fernandez, Allan Patrick G Macabeo, Hong-Thih Lai, Jong-Chin Huang, Chung-Der Hsiao: Acute and Sub-Chronic Exposure to Artificial Sweeteners at the Highest Environmentally Relevant Concentration Induce Less Cardiovascular Physiology Alterations in Zebrafish Larvae. In: Biology, 10, 2021, 548-565
2021Von Novi O De Leon, Joe Anthony H Manzano, Delfin Yñigo H Pilapil, Rey Arturo T Fernandez, James Kyle Anthony R Ching, Mark Tristan J Quimque, Jay Carl M Agbay, Kin Israel R Notarte, Allan Patrick G Macabeo: Anti-HIV reverse transcriptase plant polyphenolic natural products with in silico inhibitory properties on seven non-structural proteins vital in SARS-CoV-2 pathogenesis. In: Journal of Genetic Engineering and Biotechnology, 19, 2021, 1-17
2021Hilbert D Magpantay, Ivane N Malaluan, Joe Anthony H Manzano, Mark Tristan Quimque, Kirstin Rhys Pueblos, Natalija Moor, Simon Budde, Porferio S Bangcaya, Demi Lim-Valle, Hans-Martin Dahse, Abbas Khan, Dong-Qing Wei, Grecebio Jonathan D Alejandro, Allan Patrick G Macabeo: Antibacterial and COX-2 Inhibitory Tetrahydrobisbenzylisoquinoline Alkaloids from the Philippine Medicinal Plant Phaeanthus ophthalmicus. In: Plants, 10, 2021, 462
2021Allan Patrick G Macabeo, Angeli Izza G Flores, Rey Arturo T Fernandez, Simon Budde, Christian Faderl, Hans-Martin Dahse, Scott G Franzblau: Antitubercular and cytotoxic polyoxygenated cyclohexane derivatives from Uvaria grandiflora. In: Natural Product Research, 35, 2021, 5229-5232
2021Mohd Tajudin Mohd Ali, Zurhana Mat Husin, Allan Patrick G Macabeo: Asymmetric Synthesis of N, O-Heterobicyclic Octanes and (−)-Geissman–Waiss Lactone. In: ACS Omega, 6, 2021, 24614-24618
2021Katherine Yasmin M Garcia, Mark Tristan J Quimque, Gian Primahana, Andreas Ratzenböck, Mark Joseph B Cano, Jeremiah Francis A Llaguno, Hans-Martin Dahse, Chayanard Phukhamsakda, Frank Surup, Marc Stadler, Allan Patrick G Macabeo: COX Inhibitory and Cytotoxic Naphthoketal-Bearing Polyketides from Sparticola junci. In: International Journal of Molecular Sciences, 22, 2021, 12379
2021Ferry Saputra, Boontida Uapipatanakul, Jiann-Shing Lee, Shih-Min Hung, Jong-Chin Huang, Yun-Chieh Pang, John Emmanuel R Muñoz, Allan Patrick G Macabeo, Kelvin H-C Chen, Chung-Der Hsiao: Co-treatment of copper oxide nanoparticle and carbofuran enhances cardiotoxicity in zebrafish embryos. In: International Journal of Molecular Sciences, 22, 2021, 8259
2021Joshua Santos, Mark Tristan Quimque, Rhenz Alfred Liman, Jay Carl Agbay, Allan Patrick G Macabeo, Mary Jho-Anne Corpuz, Yun-Ming Wang, Tsai-Te Lu, Chia-Her Lin, Oliver B Villaflores: Computational and Experimental Assessments of Magnolol as a Neuroprotective Agent and Utilization of UiO-66 (Zr) as Its Drug Delivery System. In: ACS Omega, 6, 2021, 24382-24396
2021Wilawan Kuephadungphan, Allan Patrick G Macabeo, Janet Jennifer Luangsa-ard, Marc Stadler: Discovery of novel biologically active secondary metabolites from Thai mycodiversity with anti-infective potential. In: Current Research in Biotechnology, 3, 2021, 160-172
2021Petrus Siregar, Michael Edbert Suryanto, Kelvin H-C Chen, Jong-Chin Huang, Hong-Ming Chen, Kevin Adi Kurnia, Fiorency Santoso, Akhlaq Hussain, Bui Thi Ngoc Hieu, Ferry Saputra, Gilbert Audira, Marri Jmelou M Roldan, Rey Arturo Fernandez, Allan Patrick G Macabeo, Hong-Thih Lai, Chung-Der Hsiao: Exploiting the Freshwater Shrimp Neocaridina denticulata as Aquatic Invertebrate Model to Evaluate Nontargeted Pesticide Induced Toxicity by Investigating Physiologic and Biochemical Parameters. In: Antioxidants, 10, 2021, 391
2021Ana Marie L. Rubenicia, Leo D. P. Cubillan, Victor Arni D. P. Sicam, Allan Patrick G. Macabeo, Oliver B. Villaflores, Agnes L. Castillo: Intraocular Pressure Reduction Effect of 0.005% Latanoprost Eye Drops in a Hyaluronic Acid-Chitosan Nanoparticle Drug Delivery System in Albino Rabbits. In: Translational Vision Science & Technology, 10, 2021, 2
2021Nemi Malhotra, Kelvin H-C Chen, Jong-Chin Huang, Hong-Thih Lai, Boontida Uapipatanakul, Marri Jmelou M Roldan, Allan Patrick G Macabeo, Tzong-Rong Ger, Chung-Der Hsiao: Physiological effects of neonicotinoid insecticides on non-target aquatic animals—an updated review. In: International Journal of Molecular Sciences, 22, 2021, 9591
2021Mark Tristan Quimque, Kin Israel Notarte, Arianne Letada, Rey Arturo Fernandez, Delfin Yñigo Pilapil IV, Kirstin Rhys Pueblos, Jay Carl Agbay, Hans-Martin Dahse, Arlette Wenzel-Storjohann, Deniz Tasdemir, Abbas Khan, Dong-Qing Wei, Allan Patrick Gose Macabeo: Potential Cancer-and Alzheimer’s Disease-Targeting Phosphodiesterase Inhibitors from Uvaria alba: Insights from In Vitro and Consensus Virtual Screening. In: ACS Omega, 6, 2021, 8403-8417
2021Priyanka Chaudhary, Jeyakumar Kandasamy, Allan Patrick Macabeo, Ramuel John Tamargo, Yong Rok Lee: Recent Advances and Strategies for the Transition‐Metal‐Catalyzed C–H Functionalization of N‐Nitrosoanilines. In: Advanced Synthesis & Catalysis, 363, 2021, 2307-2060
2021Mark Tristan J Quimque, Kin Israel R Notarte, Rey Arturo T Fernandez, Mark Andrew O Mendoza, Rhenz Alfred D Liman, Justin Allen K Lim, Luis Agustin E Pilapil, Jehiel Karsten H Ong, Adriel M Pastrana, Abbas Khan, Dong-Qing Wei, Allan Patrick G Macabeo: Virtual screening-driven drug discovery of SARS-CoV2 enzyme inhibitors targeting viral attachment, replication, post-translational modification and host immunity evasion infection mechanisms. In: Journal of Biomolecular Structure and Dynamics, 39, 2021, 4316-4333
2021Katherine Yasmin M Garcia, Chayanard Phukhamsakda, Mark Tristan J Quimque, Kevin D Hyde, Marc Stadler, Allan Patrick G Macabeo: [HTML] from acs.org Full View Catechol-Bearing Polyketide Derivatives from Sparticola junci. In: Journal of Natural Products, 84, 2021, 2053-2058
2020D. L. Resuello, S. B. Lirio, A. E. Porto, A. P. G. Macabeo, H.-Y. Huang, M. J.-A. T. Corpuz, O. B. Villaflores: ?-secretase 1 inhibitory activity and AMP-activated protein kinase activation of Callyspongia samarensis extracts. In: Natural Products Research, 2020, 525-529
2020A. P. G. Macabeo, L. A. E. Pilapil, K. Y. M.Garcia, M. T. J. Quimque, C. Phukhamsakda, A. J. C. Cruz, K. D. Hyde, M. Stadler: Alpha-glucosidase and lipase-inhibitory phenalenones from a new species of Pseudolophiostoma originating from Thailand. In: Molecules, 2020, 965-976
2020Joshua H Santos, Mark Tristan J Quimque, Allan Patrick G Macabeo, Mary Jho-Anne T Corpuz, Yun-Ming Wang, Tsai-Te Lu, Chia-Her Lin, Oliver B Villaflores: Enhanced oral bioavailability of the pharmacologically active lignin magnolol via Zr-based metal organic framework impregnation. In: Pharmaceutics, 12, 2020, 437
2020Ausana Mapook, Allan Patrick G Macabeo, Benjarong Thongbai, Kevin D Hyde, Marc Stadler: Polyketide-Derived Secondary Metabolites from a Dothideomycetes Fungus, Pseudopalawania siamensis gen. et sp. nov.,(Muyocopronales) with Antimicrobial and Cytotoxic Activities. In: Biomolecules, 2020, 569-592
2020Mark Tristan M. Quimque, Mark S. Mandigma, Justin Allen K. Lim, Simon Budde, Hans-Martin Dahse, Oliver B. Villaflores, Arnold V. Hallare, Allan Patrick G. Macabeo: Synthesis, Characterization, and Molecular Docking Studies of N-Acylated Butyro and Valerolactam Derivatives with Antiproliferative and Cytotoxic Activities. In: Letters in Drug Design and Discovery, 17, 2020, 725-730
2020A. P. G. Macabeo, A. J. C. Cruz, A. Narmani, M. Arzanlou, A. Babai-Ahari, L. A. E. Pilapil, K. Y. M. Garcia, V. Huch, M. Stadler: Tetrasusbtituted ?-pyrone derivatives from the endophytic fungus, Neurospora udagawae. In: Phytochemistry Letters, 2020, 147-151
2019K. I. R. Notarte, M. K. P. Devanadera, Anna Beatriz R. Mayor, M. C. A. Cada, M. H. Pecundo, A. P. G. Macabeo: Antimicrobial, antioxidant and toxicity of fungal endophytes Colletotrichum sp. and Nigrospora sphaerica isolated from Uvaria grandiflora. In: Philippine Journal of Science, 2019, 503-510
2019A. P. G. Macabeo, M. Stadler: Fungal-derived natural products inhibitory to human pathogenic viruses (section 9). The amazing potential of fungi: 50 ways we can exploit fungi industrially. In: Fungal Diversity, 2019, 1-136
2019C. Phukhamsakda, A. P. G. Macabeo, T. Cheng, V. Huch, K. D. Hyde, M. Stadler: Sparticolins A–G, biologically active spirodioxynapthalene derivatives from the ascomycocete Sparticola junci. In: Journal of Natural Products, 2019, 2878-2885
2019W. Kuephadungphan, A. P. G. Macabeo, J. J. Luangsa-ard, K. Tasanathai, D. Thanakitpipattana, S. Phongpaichit, K. Yuyama, M. Stadler: Studies on the biologically active secondary metabolites of the new spider parasitic fungus Gibellula gamsii. In: Mycological Progress, 2019, 1-12
2019A. P. G. Macabeo, M.L.M.Mathias, M.T.J.Quimque, K.R.S.Pueblos, M.T.M.Ali, S.G. Franzblau: Synthesis, Antitubercular Activity and Molecular Docking Studies of Benzyl-modified 8-Hydroxyquinolines. In: Philippine Journal of Health Research and Development, 2019, 1-9
2018C. Phukhamsakda, A. P. G. Macabeo, K. Yuyama, K. D. Hyde, M. Stadler: Biofilm inhibitory abscisic acid derivatives from the plant-associated Dothideomycete fungus, Roussoella sp.. In: Molecules, 2018, 2190-2197
2017A. P. G. Macabeo, A. R. Letada, S. Budde, C. Faderl, S. Franzblau, H-M. Dahse, G. J. D. Alejandro, G. K. Pierens, M. J. Garson: Antitubercular and cytotoxic chlorinated seco-cyclohexenes from Uvaria alba. In: Journal of Natural Products, 2017, 3319-3323
2017A. P. G. Macabeo, P. Y. M. Rubio, T. Higuchi, N. Umezawa, C. Faderl, S. Budde, P. S. Bangcaya, G. J. D. Alejandro: Polyoxygenated seco-cyclohexenes and other constituents from Uvaria valderramensis. In: Biochemical Systematics and Ecology, 2017, 200-204
2017M. T. M. Ali, S. A. Aliasak, A. P. G. Macabeo: Short asymmetric synthesis of a model monomeric unit for ????peptide foldamers based on ?-amino linked D-leucine – cis-?-butyrolactone ?-acetic acid conjugate. In: Organic Communications, 2017, 99-103
2017M. T. M. Ali, H. Zahari, S. A. Aliasak, S. M. Lim, K. Ramasamy, A. P. G. Macabeo: Synthesis, characterization and cytotoxic activity of betulinic acid and seco-betulinic acid derivatives against human colorectal carcinoma. In: Oriental Journal of Chemistry, 2017, 242-248
2017A. V. Hallare, J. L. A. C. Chan, B. M. S. P. Tan, P. Y. M. Rubio, E. G. Dapat, A. P. G. Macabeo: Toxicological Analysis of Phthalates from Dust Samples Collected in Selected Philippine Light Rail Transit Stations. In: Nature Environment and Pollution Technology, 2017, 11-19
2016A. V. Hallare, A. N. Y. Morales, B. L. A. S. Tanalgo, P. Y. M. Rubio, A. P. G. Macabeo: Assessment of embryotoxicity of urban highway runoff in Manila using the zebrafish (Danio rerio) embryo toxicity (ZFET) test. In: Research Journal of Pharmaceutical, Biological and Chemical Sciences, 2016, 43-51
2016A. V. Hallare, J. M. N. Bolinao, J. G. T. Go, P. Y. M. Rubio, C. Faderl, A. P. G. Macabeo: Comparative toxicological analysis of polycyclic aromatic hydrocarbon (PAH)-rich soot extracts from gasoline and LPG-fueled taxis using the Zebrafish Embryo Toxicity (ZFET) test. In: Research Journal of Pharmaceutical, Biological and Chemical Sciences, 2016, 159-169
2016M. R. Baltazar, S. Budde, C. Faderl, A. B. Verano, A. P. G. Macabeo: Enantioselective chiral 2’-pyridyl-2-imidazoline organocatalyzed Aldol reactions in brine. In: Acta Manilana, 2016, 33-39
2016M. G. M. Galang, A. P. G. Macabeo, W.-C. Chang, M. Isobe, M. A. M. Aguinaldo: Glucosides from the unripe fruit juice of Carica papaya Linn. (Caricaceae) cultivar ‘Red Lady’ with antioxidant activity. In: Journal of Functional Foods, 2016, 358-362
2016P. B. T. So, P. Y. M. Rubio, S. Lirio, A. P. G. Macabeo, H.-Y. Huang, M. J.-A. T. Corpuz, O. B. Villaflores: In vitro angiotensin I converting enzyme inhibition by a peptide isolated from Chiropsalmus quadrigatus Haeckel (box jellyfish) venom hydrolysate. In: Toxicon, 2016, 77-83
2016A. P. G. Macabeo, O. B. Villaflores, S. G. Franzblau, M. A. M. Aguinaldo: Natural products-based discovery of antitubercular agents from Philippine medicinal plants – A review. In: Acta Manilana, 2016, 87-98
2015A. P. G. Macabeo*, P. Y. M. Rubio, M. Knorn, G. J. D. Alejandro: An ?-glucosidase inhibitor from the Philippine endemic Annonaceae plant, Drephananthus philippinensis. In: Proceedia Chemistry, 2015, 36-39
2015J. L. A. Covarubias, A. P. G. Macabeo, O. B. Villaflores, M. Knorn, P. Kohls, A. V. Bayquen: Antibacterial activity and concentration-dependent modulation of angiogenesis of the saponins from Schefflera luzoniensis. In: Research Journal of Pharmaceutical, Biological and Chemical Sciences, 2015, 418-422
2015A. V. Hallare, A. L. Santos, M. N. A. R. Uy, A. P. G. Macabeo: Avicennia marina (Forssk.) Vierh. as phytoaccumulator of sediment heavy metals in the Las Piñas – Parañaque Critical Habitat and Ecotourism Area (Philippines). In: Research Journal of Pharmaceutical, Biological and Chemical Sciences, 2015, 392-398
2015A. P. G. Macabeo, K. Y. M. Garcia, C. F. de Guzman, W. S. Vidar, S. G. Franzblau: Steroids and pentacyclic triterpenoids from Voacanga megacarpa. In: Research Journal of Pharmaceutical, Biological and Chemical Sciences, 2015, 432-435
2014A. P. G. Macabeo, A. D. C. Lopez, S. Schmidt, J. Heilmann, H.-M. Dahse, S. G. Franzblau, G. J. D. Alejandro: Antitubercular and cytotoxic constituents from Goniothalamus sibuyanensis. In: Records of Natural Products, 2014, 41-45
2014S. Lirio, A. P. G. Macabeo, M. Knorn, P. Kohls, Y. Wang, S. G. Franzblau, A. M. Aguinaldo: Antitubercular constituents from Premna odorata Blanco. In: Journal of Ethnopharmacology, 2014, 471-474
2014E. M. Paragas, D. Gehle, K. Krohn, S. Franzblau, A. P. G. Macabeo: Antitubercular flavonol derivatives from Uvaria rufa. In: Research Journal of Pharmaceutical, Biological and Chemical Sciences, 2014, 856-859
2014A. P. G. Macabeo, F. dZ. Guce: Bromopyrrole-imidazole alkaloids from Acanthella carteri Dendy (Axinellidae). In: Research Journal of Pharmaceutical, Biological and Chemical Sciences, 2014, 720-723
2014E. A. Quinto, C. P. Garcia, F. Abrantes, A. P. G. Macabeo, L. Lioanag: Gordonia terrae USTCMS 1066: Its Taxonomy, Antimicrobial Susceptibility Profile, Imidazolium Sensitivity and Evaluation as an Initial Screening Agent for Anti-TB Compounds and Natural Products. In: Philippine Journal of Systematic Biology, 2014, 27-45
2014A. P. G. Macabeo: Psychopharmacological indole alkaloids from terrestrial plants (Chapter 3). In: R. B. Raffa, Kratom (Biak-Biak) and Related Compounds: the Chemistry and Pharmacology of Opioids from a Non-Opium Source. CRC Press Taylor and Francis Group, 2014. 23-38
2014A. P. G. Macabeo, C. A. Lee: Sterols and triterpenes from the non-polar antitubercular fraction of Abutilon indicum. In: Pharmacognosy Journal, 2014, 49-52
2014A. P. G. Macabeo, J. Cattani: Synthetic approaches towards furylparaconic acid methyl ester – An important intermediate for the synthesis of Pseudopterogorgia diterpenoids. In: Research Journal of Pharmaceutical, Biological and Chemical Sciences, 2014, 300-305
2014A. P. G. Macabeo*, F. P. A. Martinez, T. Kurtán, L. Tóth, A. Mándi, S. Schmidt, J. Heilmann, G. J. D. Alejandro, D. G. Nagle, H.-M. Dahse, S. G. Franzblau: Tetrahydroxanthene-1,3(2H)-dione derivatives from Uvaria valderramensis. In: Journal of Natural Products, 2014, 2711-2715
2013C. J. H. Acosta, A. P. G. Macabeo, L. A. Santiago: Assessment of the antiurolithiatic and antioxidant properties of Ficus pseudopalma. In: Current Research in Biomedical and Pharmaceutical Sciences, 2013, 22-30
2013W. S. Vidar, A. P. G. Macabeo, P. Kohls, M. Knorn, A. M. Aguinaldo: Polymethoxylated flavones from Micromelum compressum. In: Biochemical Systematics and Ecology, 2013, 48-50
2012A. P. G. Macabeo, C. W. Lehmann, O. Reiser: . Diastereoselective synthesis of enantiopure ?-butenolide-butyrolactones towards Pseudopterogorgia lactone furanocembranoid substructures. In: Synlett, 2012, 2909-2012
2012B. Panlilio, A. P. G. Macabeo, M. Knorn, P. Kohls, P. Richomme, S. F. Kouam, D. Gehle, K. Krohn, S. G. Franzblau, Q. Zhang, M. A. M. Aguinaldo: A lanostane aldehyde from Momordica charantia. In: Phytochemistry Letters, 2012, 682-684
2012P. G. D. Cabuang, B. S. Exconde, V. Lim, D. K. M. Padilla, S. R. Salas, B. O. C. Lemana, A. P. G. Macabeo, G. J. D. Alejandro: A novel species of Uvaria (Annonaceae) based on cpDNA markers with potential medicinal properties. In: Philippine Journal of Systematic Biology, 2012, 1-16
2012A. P. G. Macabeo, F A. Tudla, K. Krohn, S. G. Franzblau: Antitubercular activity of the semi-polar extractives of Uvaria rufa. In: Asian Pacific Journal of Tropical Medicine, 2012, 777-780
2012A. P. G. Macabeo, D. Gehle, K. Krohn, S. G. Franzblau, M. A. M. Aguinaldo: Photoactivated [3+2] addition of 6,7-seco-angustilobine B to fullerene [C60]. In: Natural Products Communication, 2012, 743-745
2012A. P. G. Macabeo, J. A. Avila, G. J. D. Alejandro, S. G. Franzblau, S. F. Kouam, H. Hussain, K. Krohn: Villarinol, a new alkenoyloxyalkenol derivative from the endemic Philippine Rubiaceae. In: Natural Products Communication, 2012, 779-780
2011A. P. G. Macabeo, A. Kreuzer, O. Reiser: Diastereoselective approaches towards arylated ?-butyrolactones and their application towards highly oxidised Pseudopterogorgia diterpenoids. In: Organic and Biomolecular Chemistry (formerly Perkin Transactions (1), 2011, 3146-3150
2011A. P. G. Macabeo, W. S. Vidar, B. Wan, S. G. Franzblau, X. Chen, M. Decker, J. Heilmann, M. A. M. Aguinaldo, G. A. Cordell: Mycobacterium tuberculosis H37Rv and cholinesterase inhibitors from Voacanga globosa. In: European Journal of Medicinal Chemistry, 2011, 3118-3123
2010M. Barbic, A. P. G. Macabeo, S. Kreft, J. Heilmann: Astragalosides from Astragalus illyricus. In: Biochemical Systematics and Ecology, 2010, 140-142
2010A. P. G. Macabeo, F. Tudla, G. J. D. Alejandro, S. F. Kouam, K. Krohn, Hidayat Hussain: Benzoylated derivatives from Uvaria rufa. In: Biochemical Systematics and Ecology, 2010, 857-860
2010O. B. Villaflores, A. P. G. Macabeo, D. Gehle, K. Krohn, S. G. Franzblau, M. A. M. Aguinaldo: Phytoconstituents from Alpinia purpurata and their in vitro inhibitory activity against Mycobacterium tuberculosis. In: Pharmacognosy Magazine, 2010, 339-344
2009A. P. G. Macabeo*, G. J. D. Alejandro, A. V. Hallare, W. S. Vidar, O. B. Villaflores: Phytochemical survey and pharmacological activities of the indole alkaloids in the genus Voacanga Thouars (Apocynaceae) - an update. In: Pharmacognosy Reviews, 2009, 132-142
2008A. P. G. Macabeo, R. W. Read, J. Brophy, G. A. Cordell, K. Krohn, D. Gehle, S. G. Franzblau, M. A. M. Aguinaldo: Activity of the extracts and indole alkaloids from Alstonia scholaris against Mycobacterium tuberculosis H37Rv. In: The Philippine Agricultural Scientist, 2008, 348-351
2008A. P. G. Macabeo, M. A. M. Aguinaldo: Chemical and phytomedicinal investigations in Lunasia amara. In: Pharmacognosy Reviews, 2008, 317-325
2008A. P. G. Macabeo, M. Villafranca, A. M. Aguinaldo, K. Krohn, H. Hussain: Clerosterols from Clerodendrum quadriloculare. In: Biochemical Systematics and Ecology, 2008, 659-660
2008A. P. G. Macabeo: Synthetic uses of ClTi(O-Pri)3 in C-C(N) Bond Formation . In: Synlett, 2008, 3247-3248
2007F. Tudla, M. A. M. Aguinaldo, K. Krohn, H. Hussain, A. P. G. Macabeo: Highly oxygenated cyclohexene metabolites from Uvaria rufa. In: Biochemical Systematics and Ecology, 2007, 45-47
2007K. Mandap, R. Marcelo, A. P. G. Macabeo, S. G. Franzblau, A. M. Aguinaldo: Phenyldecanoids from the antitubercular fractions of the Philippine ginger (Zingiber officinale). In: ACGC Chemical Research Communications, 2007, 20-22
2007V. Dalangin-Mallari, A. P. G. Macabeo, L. T. Byrne, T. Yamauchi, F. Abe, S. G. Franzblau, A. M. Aguinaldo: Quinoline alkaloids from Lunasia amara inhibit Mycobacterium tuberculosis H37Rv in vitro. In: International Journal of Antimicrobial Agents, 2007, 744-746
2006A. P. G. Macabeo, L. T. Byrne, S. G. Franzblau, M. A. M. Aguinaldo: 19,20E-Akuammidine from the bioactive alkaloid fraction of Alstonia scholaris leaves. In: ACGC Chemical Research Communications , 2006, 11-13
2005A. P. G. Macabeo, K. Krohn, D. Gehle, G. A. Cordell, S. G. Franzblau, M. A. M. Aguinaldo. Indole alkaloids from the leaves of Philippine Alstonia scholaris. In: Phytochemistry, 2005, 1158-1162
1999A. P. G. Macabeo, S. G. Franzblau, G. A. Cordell, M.A.M. Aguinaldo: A plumeran indole alkaloid from the antitubercular alkaloid extract of Catharanthus roseus (Linn.) G. Don (Apocynaceae). In: Acta Manilana, 1999, 51-54