Prof. Dr. Xiao-Yu Hu

Profile

Academic positionFull Professor
Research fieldsPreparative and Physical Chemistry of Polymers,Organic Molecular Chemistry
KeywordsFunctional Materials, Supramolecular chemistry, Host-guest interaction, Dual-targeted nanocarrier, Drug/gene co-delivery
Honours and awards

2021: National Natural Science Foundation of China for Sino-German Mobility Program

2018: Natural Science Foundation of Jiangsu Province for Outstanding Young Scholar

2018: The Outstanding Young Scholar of Jiangsu Province

2018: The teaching and research achievement award of Jiangsu Province

2015: National Natural Science Foundation of China

2014: Natural Science Foundation of Jiangsu Province

2013: National Natural Science Foundation of China

2012: China National Postdoctoral Science Foundation

Current contact address

CountryPeople's Republic of China
CityNANJING
InstitutionNanjing University of Aeronautics and Astronautics
InstituteMaterial Science and Technology

Host during sponsorship

Prof. Dr. Carsten SchmuckInstitut für Organische Chemie, Universität Duisburg-Essen, Essen
Start of initial sponsorship01/07/2016

Programme(s)

2015Humboldt Research Fellowship Programme for Experienced Researchers

Publications (partial selection)

2021Minzan Zuo and Weirui Qian and Min Hao and Kaiya Wang and Xiao-Yu Hu and Leyong Wang: An AIE singlet oxygen generation system based on supramolecular strategy. In: Chinese Chemical Letters, 32, 2021, 1381-1384
2021Wang, Kaiya and Velmurugan, Krishnasamy and Li, Bin and Hu, Xiao-Yu: Artificial light-harvesting systems based on macrocycles-assisted supramolecular assembly in aqueous media. In: Chem. Commun., 2021, -
2021Tian, Xueqi and Zuo, Minzan and Niu, Pengbo and Velmurugan, Krishnasamy and Wang, Kaiya and Zhao, Yue and Wang, Leyong and Hu, Xiao-Yu: Orthogonal Design of a Water-Soluble meso-Tetraphenylethene-Functionalized Pillar[5]arene with Aggregation-Induced Emission Property and Its Therapeutic Application. In: ACS Applied Materials \& Interfaces, 13, 2021, 37466-37474
2021Wang, Kaiya and Jordan, Jacobs H. and Velmurugan, Krishnasamy and Tian, Xueqi and Zuo, Minzan and Hu, Xiao-Yu and Wang, Leyong: Role of Functionalized Pillararene Architectures in Supramolecular Catalysis. In: Angewandte Chemie International Edition, 60, 2021, 9205-9214
2020Hao, Min and Sun, Guangping and Zuo, Minzan and Xu, Zuqiang and Chen, Yuan and Hu, Xiao-Yu and Wang, Leyong: A Supramolecular Artificial Light-Harvesting System with Two-Step Sequential Energy Transfer for Photochemical Catalysis. In: Angewandte Chemie International Edition, 59, 2020, 10095-10100
2020Gigante, Alba and Sijbesma, Eline and Sánchez-Murcia, Pedro A. and Hu, Xiaoyu and Bier, David and Bäcker, Sandra and Knauer, Shirley and Gago, Federico and Ottmann, Christian and Schmuck, Carsten: A Supramolecular Stabilizer of the 14-3-3ζ/ERα Protein-Protein Interaction with a Synergistic Mode of Action. In: Angewandte Chemie International Edition, 59, 2020, 5284-5287
2020Sun, Guangping and Qian, Weirui and Jiao, Jianmin and Han, Tingting and Shi, Yukun and Hu, Xiao-Yu and Wang, Leyong: A highly efficient artificial light-harvesting system with two-step sequential energy transfer based on supramolecular self-assembly. In: J. Mater. Chem. A, 8, 2020, 9590-9596
2020Wang, Kaiya and Jordan, Jacobs H. and Hu, Xiao-Yu and Wang, Leyong: Supramolecular Strategies for Controlling Reactivity within Confined Nanospaces. In: Angewandte Chemie International Edition, 59, 2020, 13712-13721
2020Qian, Weirui and Zuo, Minzan and Sun, Guangping and Chen, Yuan and Han, Tingting and Hu, Xiao-Yu and Wang, Ruibing and Wang, Leyong: The construction of an AIE-based controllable singlet oxygen generation system directed by a supramolecular strategy. In: Chem. Commun., 56, 2020, 7301-7304
2019Jiang, Hao and Hu, Xiao-Yu and Mosel, Stefanie and Knauer, Shirley K. and Hirschhäuser, Christoph and Schmuck, Carsten: A Branched Tripeptide with an Anion-Binding Motif as a New Delivery Carrier for Efficient Gene Transfection. In: ChemBioChem, 20, 2019, 1410-1416
2019Sun, Guangping and He, Zhimei and Hao, Min and Xu, Zuqiang and Hu, Xiao-Yu and Zhu, Jun-Jie and Wang, Leyong: Bifunctional supramolecular prodrug vesicles constructed from a camptothecin derivative with a water-soluble pillar[5]arene for cancer diagnosis and therapy. In: Chem. Commun., 55, 2019, 10892-10895
2019Sun, Guangping and He, Zhimei and Hao, Min and Zuo, Minzan and Xu, Zuqiang and Hu, Xiao-Yu and Zhu, Jun-Jie and Wang, Leyong: Dual acid-responsive bola-type supramolecular vesicles for efficient intracellular anticancer drug delivery. In: J. Mater. Chem. B, 7, 2019, 3944-3949
2019Wang, Sai Gao, Wei Hu, Xiao-Yu Shen, Ying-Zhong Wang, Leyong: Supramolecular strategy for smart windows. In: Chemical Communications, 2019, 4137-4149
2018Shao, Wei Liu, Xin Sun, Guangping Hu, Xiao-Yu Zhu, Jun-Jie Wang, Leyong: Construction of drug-drug conjugate supramolecular nanocarriers based on water-soluble pillar[6]arene for combination chemotherapy. In: Chemical Communications, 2018, 9462-9465
2018Hu Xiao-Yu Ehlers Martin Wang Tingting Zellermann Elio Mosel Stefanie Jiang Hao Ostwaldt Jan-Erik Knauer Shirley K. Wang Leyong Schmuck Carsten: Formation of twisted ?-sheet tapes from a self-complementary peptide based on novel pillararene-GCP host-guest interaction with gene transfection properties. In: Chemistry – A European Journal, 2018, 9754-9759
2018Hu, Xiao-Yu Gao, Lei Mosel, Stefanie Ehlers, Martin Zellermann, Elio Jiang, Hao Knauer, Shirley K. Wang, Leyong Schmuck, Carsten: From supramolecular vesicles to micelles: Controllable construction of tumor-targeting nanocarriers based on host–guest interaction between a pillar[5]arene-based prodrug and a RGD-sulfonate guest. In: Small, 2018, 1803952
2018Zuo, Minzan Qian, Weirui Li, Tinghan Hu, Xiao-Yu Jiang, Juli Wang, Leyong: Full-color tunable fluorescent and chemiluminescent supramolecular nanoparticles for anti-counterfeiting inks. In: ACS Applied Materials & Interfaces, 2018, 39214-39221
2018Shuwen Guo, Yongshang Song, Yuling He, Xiao-Yu Hu,* and Leyong Wang*: Highly Efficient Artificial Light-Harvesting Systems Constructed in Aqueous Solution Based on Supramolecular Self-Assembly. In: Angewandte Chemie International Edition, 2018, 1-6
2018Xu, Zuqiang Wang, Sai Hu, Xiao-Yu Jiang, Juli Sun, Xiaoqiang Wang, Leyong: Sunlight-induced photo-thermochromic supramolecular nanocomposite hydrogel film for energy-saving smart window. In: Solar RRL, 2018, 1800204
2018Wang, Sai Xu, Zuqiang Wang, Tingting Xiao, Tangxin Hu, Xiao-Yu Shen, Ying-Zhong Wang, Leyong: Warm/cool-tone switchable thermochromic material for smart windows by orthogonally integrating properties of pillar[6]arene and ferrocene. In: Nature Communications, 2018, 1737
2017Xin Liu, Keke Jia, Yichen Wang, Wei Shao, Chenhao Yao, Luming Peng, Dongmei Zhang,* Xiao-Yu Hu,* and Leyong Wang: Dual-Responsive Bola-Type Supra-Amphiphile Constructed from Water-Soluble Pillar[5]arene and Naphthalimide-Containing Amphiphile for Intracellular Drug Delivery. In: ACS Applied Materials & Interfaces, 2017, 4843-4850
2017Xin Liu, Wei Shao, Yanjing Zheng, Chenhao Yao, Luming Peng, Dongmei Zhang, Xiao-Yu Hu* and Leyong Wang: GSH-Responsive supramolecular nanoparticles constructed by b-D-galactose-modified pillar[5]arene and camptothecin prodrug for targeted anticancer drug delivery. In: Chemical Communications, 2017, 8596-8599
2017Lei Gao, Tingting Wang, Keke Jia, Xuan Wu, Chenhao Yao, Wei Shao, Dongmei Zhang, Xiao-Yu Hu,* and Leyong Wang*: Glucose-Responsive Supramolecular Vesicles BasedonWater- Soluble Pillar[5]arene and Pyridylboronic Acid Derivatives for ControlledInsulin Delivery. In: Chemistry – A European Journal, 2017, 6605-6614
2017Hao Jiang, Xiao-Yu Hu, Stefanie Schlesiger, Mao Li, Eilo Zellermann, Shirley K. Knauer, and Carsten Schmuck*: Morphology-Dependent Cell Imaging by Using a Self-Assembled Diacetylene Peptide Amphiphile. In: Angewandte Chemie, 2017, 14718-14722
2017Shuwen Guo, Tingxizi Liang, Yongshang Song, Ming Cheng, Xiao-Yu Hu,* Jun-Jie Zhu* and LeyongWang*: Supramolecular polymersomes constructed from water-soluble pillar[5]arene and cationic poly (glutamamide)s and their applications in targeted anticancer drug delivery. In: Polymer Chemistry, 2017, 5718-5725
2017Xiao-Yu Hu and Leyong Wang: Two sides to supramolecular drug delivery systems. In: Supramolecular Chemistry, 2017, 1-3
2016Xiao-Yu Hu, Xin Liu, Wenyi Zhang, Shan Qin, Chenhao Yao, Yan Li, Derong Cao, Luming Peng, and Leyong Wang*: Controllable Construction of Biocompatible Supramolecular Micelles and Vesicles by Water-Soluble Phosphate Pillar[5,6]arenes for Selective Anti-Cancer Drug Delivery. In: Chemistry of Materials, 2016, 3778-3788
2016Mengfei Ni, Ning Zhang, Wei Xia, Xuan Wu, Chenhao Yao, Xin Liu, Xiao-Yu Hu, Chen Lin,* and Leyong Wang*: Dramatically Promoted Swelling of a Hydrogel by Pillar[6]arene? Ferrocene Complexation with Multistimuli Responsiveness. In: Journal of the American Chemical Society, 2016, 6643-6649
2016Shuwen Guo, Xin Liu, Chenhao Yao, Chengxi Lu, Qingxin Chen, Xiao-Yu Hu* and Leyong Wang*: Photolysis of a bola-type supra-amphiphile promoted by water-soluble pillar[5]arene-induced assembly. In: Chemical Communications, 2016, 10751-10754
2016Xuan Wu, Lei Gao, Xiao-Yu Hu,* and Leyong Wang: Supramolecular Drug Delivery Systems Based on Water-Soluble Pillar[n]arenes. In: The Chemical Record, 2016, 1216-1227