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Profile
| Academic position | Full Professor |
|---|---|
| Research fields | Immunology,Cell Biology |
| Keywords | stem cells, cell fate decisions, macrophages, cellular self renewal, regeneration |
| Honours and awards | 2026: EIC Transition Laureate 2018: Alexander-von-Humboldt Professor 2017: CNRS Silver Medal 2017: FRM Group Laureate 2016: ERC Advanced Laureate 2014: Einstein BIH Visiting Fellow 2014: EMBO Member 2014: FRM Group Laureate 2010: Grandes Avancées Honour from the French Academy of Science 1999: ATIPE Young Investigator Award 1992: EMBO Postdoctoral Fellow 1991: Böhringer Ingelheim Fonds Fellow 1989: Josephine de Karman Fellow 1989: Julian D. Morgan Fellow of the University of California, Berkeley 1988: Fellow of the Regents of the University of California, Berkeley |
Current contact address
| Country | Germany |
|---|---|
| City | Dresden |
| Institution | Technische Universität Dresden |
| Institute | Center for Regenerative Therapies Dresden (CRTD) |
Host during sponsorship
| Prof. Dr. Elly Tanaka | Technische Universität Dresden, Dresden |
|---|---|
| Prof. Dr.-Ing. habil. Dr. h.c. mult. Hans Müller-Steinhagen | Technische Universität Dresden, Dresden |
| Prof. Dr. Ezio Bonifacio | Technische Universität Dresden, Dresden |
| Prof. Dr.-Ing. habil. Dr. h.c. mult. Hans Müller-Steinhagen | Dresden International University GmbH, Dresden |
| Prof. Dr. Ursula M. Staudinger | Technische Universität Dresden, Dresden |
| Prof. Dr. Elly Tanaka | Research Institute of Molecular Pathology (IMP), Wien |
| Prof. Dr. Ezio Bonifacio | Biotechnologisches Zentrum (Biotec), Technische Universität Dresden, Dresden |
| Start of initial sponsorship | 01/04/2018 |
Programme(s)
| 2017 | Alexander von Humboldt Professorship |
|---|
Nominator's project description
| Our bodies are continually changing. In many organs – like the intestines, the skin or the blood – stem cells constantly create new cells to replace those that are lost. This is the way the tissue is preserved or regenerates after injury. Sieweke’s special field are the mechanisms by which cells of the immune system are generated and the role of these cells in preserving tissue function and regeneration. He has produced internationally recognised work that could help to develop new approaches to cellular therapy. It was Sieweke’s team, for example, who discovered an emergency mechanism which quickly responds to severe infections by supplying the body with new immune cells that fight the invading pathogens. These mechanisms might one day be used in bone marrow transplants to help rebuild the immune system more quickly. Sieweke’s research also showed that some mature immune cells, called macrophages, can divide indefinitely and keep up their numbers by using similar mechanisms as stem cells. The hope is that his research will help to activate these mechanisms when regeneration fails or to supply large numbers of macrophages for cellular therapies. Sieweke’s role as Humboldt Professor at Technische Universität Dresden will be to position the university more firmly at the interface of immunology and tissue regeneration and to drive new medical applications in this area. |