Dr. Matteo Aldeghi

Profile

Academic positionPost Doc
Research fieldsBiophysical Chemistry,Biophysics
Keywordsfree energy calculations, protein engineering, catalysis, enzyme design, molecular dynamics

Current contact address

CountryUnited Kingdom
CityOxford
InstitutionUniversity of Oxford
InstituteDepartment of Biochemistry

Host during sponsorship

Prof. Dr. Bert L. GrootComputational Biomolecular Dynamics Group, Max-Planck-Institut für Multidisziplinäre Naturwissenschaften, Göttingen
Start of initial sponsorship01/06/2017

Program(s)

2017Humboldt Research Fellowship Programme for Postdocs

Publications (partial selection)

2019Ai Woon Yee, Matteo Aldeghi, Matthew P Blakeley, Andreas Ostermann, Philippe J Mas, Martine Moulin, Daniele de Sanctis, Matthew W Bowler, Christoph Mueller-Dieckmann, Edward P Mitchell, Michael Haertlein, Bert L de Groot, Elisabetta Boeri Erba, V Trevor Forsyth: A molecular mechanism for transthyretin amyloidogenesis. In: Nature Communications, 2019, 925
2019Matteo Aldeghi, Bert L de Groot, Vytautas Gapsys: Accurate Calculation of Free Energy Changes upon Amino Acid Mutation. In: Tobias Sikosek, Computational Methods in Protein Evolution. Humana Press, 2019. 19-47
2018Matteo Aldeghi, Vytautas Gapsys, Bert L. de Groot: Accurate Estimation of Ligand Binding Affinity Changes upon Protein Mutation. In: ACS Central Science, 2018, 1708-1718