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Profile
| Academic position | Post Doc |
|---|---|
| Research fields | Organic Molecular Chemistry |
| Keywords | Proteolysis-targeting Chimeras, Protein degradation, Pseudokinases, Chemical Biology, Drug design |
| Honours and awards | 2019: Klaus-Grohe-Preis für Medizinische Chemie |
Current contact address
| Country | Germany |
|---|---|
| City | Dortmund |
| Institution | Max-Planck-Institut für molekulare Physiologie |
| Institute | Abteilung Chemische Biologie |
Host during sponsorship
| Prof. Dr. Craig M. Crews | Molecular, Celluar and Developmental Biology, Chemistry, Pharmacology, Yale University, New Haven |
|---|---|
| Start of initial sponsorship | 01/06/2017 |
Programme(s)
| 2017 | Feodor Lynen Research Fellowship Programme for Postdocs |
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Publications (partial selection)
| 2018 | Philipp M.Cromm, Kusal Samarasinghe, John Hines, Craig M. Crews: Addressing Kinase-Independent Functions of Fak via PROTAC-mediated Degradation. In: Journal of the American Chemical Society, 2018, 17019-17026 |
|---|---|
| 2018 | George M. Burslem, Philipp Ottis, Saul Jaime?Figueroa, Alicia Morgan, Philipp M. Cromm, Momar Toure, Craig M. Crews: Efficient Synthesis of Immunomodulatory Drug Analogues Enables Exploration of StructureDegradation Relationships. In: ChemMedChem, 2018, 1508-1512 |
| 2017 | Philipp Ottis, Momar Toure, Philipp M. Cromm, Eunhwa Ko, Jeffrey L. Gustafson, Craig M. Crews: Assessing Different E3 Ligases for Small Molecule Induced Protein Ubiquitination and Degradation. In: ACS Chem. Biol., 2017, 2570-2578 |
| 2017 | Philipp M. Cromm, Craig M. Crews: Targeted Protein Degradation: from Chemical Biology to Drug Discovery. In: Cell Chem. Biol., 2017, p1181-1190 |
| 2017 | Philipp M. Cromm, Craig M. Crews : The Proteasome in Modern Drug Discovery: Second Life of a Highly Valuable Drug Target. In: ACS Central Science, 2017, 830-838 |