Prof. Dr. Artur Cesar Fassoni

Profile

Academic positionAssociate Professor, Senior Lecturer, Reader
Research fieldsMathematics in biology and other natural sciences,Epidemiology and Medical Biometrics/Statistics,Haematology, Oncology
Keywordshematological cancers, treatment optimization, tumor-immune interactions, differential equations, mathematical biology
Honours and awards

2023: Experienced Researcher - CAPES-Humboldt Research Fellowship

Current contact address

CountryBrazil
CityItajubá
InstitutionUniversidade Federal de Itajubá (UNIFEI)
InstituteInstituto de Matemática e Computação

Host during sponsorship

Priv. Doz. Dr. Ingmar GlaucheInstitut für Medizinische Informatik und Biometrie, Technische Universität Dresden, Dresden
Start of initial sponsorship01/11/2023

Programme(s)

2022CAPES-Humboldt Research Fellowship Programme for Experienced Researchers

Publications (partial selection)

2026Vilela, Yuri Garcia and Thielecke, Lars and Fassoni, Artur C. and Glauche, Ingmar: Long-term clonal analysis using stochastic models reveals heterogeneity and quiescence of hematopoietic stem cells. In: Computers in Biology and Medicine, 208, 2026, 111650
2025Paix{\~a}o, Emanuelle A. and Barros, Luciana R. C. and Fassoni, A. C. and Almeida, Regina C.: Healthy B cells: Allies or adversaries of CAR-T cell immunotherapy?. In: Computers in Biology and Medicine, 196, 2025, 110797
2025Fassoni, Artur C. and Glauche, Ingmar: Math models expose myeloid bias mechanisms in hematopoiesis. In: Blood, 145, 2025, 1231--1232
2025Santurio, D. and Barros, Luciana R. C. and Glauche, I. and Fassoni, A. C.: Mathematical modeling unveils the timeline of CAR-T cell therapy and macrophage-mediated cytokine release syndrome. In: PLOS Computational Biology, 21, 2025, e1012908
2025Fassoni, Artur C. and Braga, Denis C.: Nonlinear dynamics of CAR-T cell therapy. In: Chaos, Solitons \& Fractals, 191, 2025, 115871
2025Vilela, Yuri G. and Fassoni, Artur C. and Neves, Armando G. M.: On the design and stability of cancer adaptive therapy cycles: Deterministic and stochastic models. In: Mathematical Biosciences, 387, 2025, 109504
2025Fassoni, Artur C. and Yong, Agnes S. M. and Clark, Richard E. and Roeder, Ingo and Glauche, Ingmar: Predicting treatment-free remission in chronic myeloid leukemia patients using an integrated model of tumor-immune dynamics. In: npj Systems Biology and Applications, 11, 2025, 115
2025Glauche, Ingmar and Fassoni, Artur C.: Speeding up for lympho-myeloid differentiation. In: Blood, 146, 2025, 650--652
2024De Araujo, Anderson L. A. and Fassoni, Artur C. and Madalena, Kamila F. L. and Salvino, Lu{\'i}s F.: Analysis and simulation of an integro-differential Lotka-Volterra model with variable reproduction rates and optimal control. In: Communications in Nonlinear Science and Numerical Simulation, 134, 2024, 108000
2024Fassoni, Artur C. and Diaz, Claudio Vidal and de Carvalho Braga, Denis and Santos, Jorge Luis Gutierrez: Dynamics and bifurcations in a model of chronic myeloid leukemia with optimal immune response windows. In: Journal of Mathematical Biology, 89, 2024, 35
2024Santurio, Daniela Silva and Paix{\~a}o, Emanuelle A. and Barros, Luciana R. C. and Almeida, Regina C. and Fassoni, Artur C.: Mechanisms of resistance to CAR-T cell immunotherapy: Insights from a mathematical model. In: Applied Mathematical Modelling, 125, 2024, 1--15
2022Ferreira, Jordana Alves and Fassoni, Artur C. and Ferreira, Joana Maria Santos and Lins, Paulo Manoel Pontes and Bottoli, Carla Beatriz Grespan: Cyproconazole Translocation in Coconut Palm Tree Using Vegetative Endotherapy: Evaluation by LC-MS/MS and Mathematical Modeling. In: Horticulturae, 8, 2022, 1099
2022Paix{\~a}o, Emanuelle A. and Barros, Luciana R. C. and Fassoni, Artur C. and Almeida, Regina C.: Modeling Patient-Specific CAR-T Cell Dynamics: Multiphasic Kinetics via Phenotypic Differentiation. In: Cancers, 14, 2022, 5576
2022Karg, Elena and Baldow, Christoph and Zerjatke, Thomas and Clark, Richard E. and Roeder, Ingo and Fassoni, Artur C. and Glauche, Ingmar: Modelling of immune response in chronic myeloid leukemia patients suggests potential for treatment reduction prior to cessation. In: Frontiers in Oncology, 12, 2022,
2021Barros, Luciana R. C. and Paix{\~a}o, Emanuelle A. and Valli, Andrea M. P. and Naozuka, Gustavo T. and Fassoni, Artur C. and Almeida, Regina C.: CARTmath -- A Mathematical Model of CAR-T Immunotherapy in Preclinical Studies of Hematological Cancers. In: Cancers, 13, 2021, 2941
2020Araujo, Anderson L. A. and Fassoni, Artur C. and Salvino, Lu{\'i}s F.: An analysis of a mathematical model describing the growth of a tumor treated with chemotherapy. In: Applied Mathematics and Nonlinear Sciences, 5, 2020, 185--204
2020De Araujo, Anderson L. A. and Fassoni, Artur C. and Salvino, Lu{\'i}s F.: Mathematical Analysis of a Non-Local Mixed ODE-PDE Model for Tumor Invasion and Chemotherapy. In: Acta Applicandae Mathematicae, 170, 2020, 415--442
2020Hähnel, Tom and Baldow, Christoph and Guilhot, Jo{\"e}lle and Guilhot, Fran{\c c}ois and Saussele, Susanne and Mustjoki, Satu and Jilg, Stefanie and Jost, Philipp J. and Dulucq, Stephanie and Mahon, Fran{\c c}ois-Xavier and Roeder, Ingo and Fassoni, Artur C. and Glauche, Ingmar: Model-based inference and classification of immunological control mechanisms from TKI cessation and dose reduction in CML patients. In: Cancer Research, 80, 2020,
2019Araujo, Anderson L. A. and Fassoni, Artur C. and Salvino, Lu{\'i}s F.: An analysis of a mathematical model describing acid-mediated tumor invasion. In: Mathematical Methods in the Applied Sciences, 42, 2019, 6686--6705
2019Yoshinari, Gerson Hiroshi and Fassoni, Artur C. and Mello, Luis Fernando and Rego, Eduardo M.: Modeling dynamics and alternative treatment strategies in acute promyelocytic leukemia. In: PLoS One, 14, 2019, e0221011
2019Fassoni, Artur C. and Carvalho Braga, Denis: Resilience Analysis for Competing Populations. In: Bulletin of Mathematical Biology, 81, 2019, 3864--3888
2019Fassoni, Artur C. and Roeder, Ingo and Glauche, Ingmar: To Cure or Not to Cure: Consequences of Immunological Interactions in CML Treatment. In: Bulletin of Mathematical Biology, 81, 2019, 2345--2395
2018Fassoni-Andrade, Alice C{\'e}sar and Fan, Fernando Mainardi and Collischonn, Walter and Fassoni, Artur C. and Paiva, Rodrigo Cauduro Dias de: Comparison of numerical schemes of river flood routing with an inertial approximation of the Saint Venant equations. In: Revista Brasileira de Recursos H{\'i}dricos, 23, 2018, e10
2018Fassoni, Artur C. and Yang, Hyun M.: Modeling dynamics for oncogenesis encompassing mutations and genetic instability. In: Mathematical Medicine and Biology, 2018, 2018, 1--27
2018Fassoni, Artur C. and Baldow, Christoph and Roeder, Ingo and Glauche, Ingmar: Reduced tyrosine kinase inhibitor dose is predicted to be as effective as standard dose in chronic myeloid leukemia: A simulation study based on phase 3 trial data. In: Haematologica, 2018, 2018, haematol.2018.194522
2016Fassoni, Artur C. and Yang, Hyun M.: An ecological resilience perspective on cancer: Insights from a toy model. In: Ecological Complexity, 30, 2016, 34--46
2016Yang, Hyun Mo and Boldrini, Jos{\'e} Luiz and Fassoni, Artur C. and Freitas, Luiz Fernando Souza and Gomez, Miller Ceron and Lima, Karla Katerine Barboza de and Andrade, Valmir Roberto and Freitas, Andr{\'e} Ricardo Ribas: Fitting the Incidence Data from the City of Campinas, Brazil, Based on Dengue Transmission Modellings Considering Time-Dependent Entomological Parameters. In: PLoS One, 11, 2016, e0152186
2014Fassoni, A. C. and Takahashi, L. T. and Dos Santos, L. J.: Basins of attraction of the classic model of competition between two populations. In: Ecological Complexity, 18, 2014, 39--48
2013Fassoni, A. C. and Martins, M. L.: Mathematical analysis of a model for plant invasion mediated by allelopathy. In: Ecological Complexity, 18, 2013, 49--58