Dr. Emmanuel Mfotie Njoya

Profile

Academic positionPost Doc
Research fieldsNatural Product Chemistry,Pharmacology
KeywordsEntamoeba histolytica, Natural compounds, Quality control, Codiaeum, Drug development
Honours and awards

2019: Alexander von Humboldt fellowship (Georg Forster Postdoctoral Program)

2017: Chinese Academy of Sciences President’s International Fellowship Initiative

2015: University of Pretoria Vice-Chancellor’s Postdoctoral Research Fellowship

2012: Sandwich Doctoral program of Deutscher Akademischer Austauschdienst (DAAD)

2011: Calmette and Yersin Program (International Network of Pasteur Institute)

Current contact address

CountryCameroon
CityYaounde
InstitutionUniversite de Yaounde I
InstituteDepartment of Biochemistry

Host during sponsorship

Prof. Dr. Timo NiedermeyerInstitut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Halle (Saale)
Prof. Dr. Timo NiedermeyerInstitut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Halle-Wittenberg
Start of initial sponsorship01/07/2019

Programme(s)

2019Georg Forster Research Fellowship Programme for Postdocs

Publications (partial selection)

2021{Foudjo Melacheu Laura}, Gertrude and {Mfotie Njoya}, Emmanuel and Jouda, Jean-Bosco and {Wakeu Kweka}, Brussine Nadege and {Djama Mbazoa}, C{\'e}line and Wang, Fei and Seguin, Elisabeth and Wandji, Jean: A new cytotoxic indole alkaloid from Tabernaemontana inconspicua stapf. In: Natural Product Research, 35, 2021, 1590--1595
2021: Cancer. Elsevier, 2021
2021{Mfotie Njoya}, Emmanuel and {Moundipa Fewou}, Paul and Niedermeyer, Timo H.J.: Codiaeum variegatum (L.) Rumph. ex A. Juss. (Euphorbiaceae): An overview of its botanical diversity, traditional uses, phytochemistry, pharmacological effects and perspectives towards developing its plant-based products. In: Journal of Ethnopharmacology, 277, 2021, 114244
2021{Mfotie Njoya}, Emmanuel: Medicinal plants, antioxidant potential, and cancer. Cancer. Elsevier, 2021. 349--357
2020Ebokaiwe, Azubuike Peter and Njoya, Emmanuel Mfotie and Sheng, Yuwen and Zhang, Zhonghui and Li, Sheng and Zhou, Zongyuan and Qiang, Zhe and Peng, Ting and Hussein, Ahmed A. and Zhang, Guolin and Lu, Xiaoxia and Li, Lin and Wang, Fei: Salinomycin promotes T-cell proliferation by inhibiting the expression and enzymatic activity of immunosuppressive indoleamine-2,3-dioxygenase in human breast cancer cells. In: Toxicology and Applied Pharmacology, 404, 2020, 115203
2019Yang, Lingling and Chen, Yang and He, Junlin and Njoya, Emmanuel Mfotie and Chen, Jianjun and Liu, Siyan and Xie, Congqiang and Huang, Wenze and Wang, Fei and Wang, Zhouyu and Li, Yuzhi and Qian, Shan: 4,6-Substituted-1H-Indazoles as potent IDO1/TDO dual inhibitors. In: Bioorganic {\&} Medicinal Chemistry, 27, 2019, 1087--1098
2019Ondua, Moise and Njoya, Emmanuel Mfotie and Abdalla, Muna Ali and McGaw, Lyndy J.: Anti-inflammatory and antioxidant properties of leaf extracts of eleven South African medicinal plants used traditionally to treat inflammation. In: Journal of Ethnopharmacology, 234, 2019, 27--35
2019Ghuman, S. and Ncube, B. and Finnie, J. F. and McGaw, L. J. and {Mfotie Njoya}, E. and Coopoosamy, R. M. and {van Staden}, J.: Antioxidant, anti-inflammatory and wound healing properties of medicinal plant extracts used to treat wounds and dermatological disorders. In: South African Journal of Botany, 126, 2019, 232--240
2019: Encyclopedia of Environmental Health. Elsevier, 2019
2019Abia, Wilfred A. and Jato, Denis M. and Mfotie, Emmanuel N.: Environmental Health Concerns in Cameroon. Encyclopedia of Environmental Health. Elsevier, 2019. 475--485
2019{Foudjo Melacheu}, Gertrude Laura and {Mfotie Njoya}, Emmanuel and Jouda, Jean-Bosco and {Wakeu Kweka}, Brussine Nadege and {Djama Mbazoa}, C{\'e}line and Wang, Fei and Wandji, Jean: Two new indole alkaloids from Tabernaemontana contorta Stapf. In: Phytochemistry Letters, 30, 2019, 116--119
2018Njoya, Emmanuel and Kamini, Melanie and Abia, Wilfred and Pechangou, Sylvain and Njayou, Frderic and Tchana, Angle and Moundipa, Paul: Acute and subchronic toxicity evaluation of the aqueous extract of Codiaeum variegatum leaves on Wistar albino rodents of both sexes. In: Journal of Complementary Medicine Research, 7, 2018, 108
2018Qiang, Zhe and Zhou, Zong-yuan and Peng, Ting and Jiang, Pu-zi and Shi, Nan and Njoya, Emmanuel Mfotie and Azimova, Bahtigul and Liu, Wan-li and Chen, Wei-hua and Zhang, Guo-lin and Wang, Fei: Inhibition of TPL2 by interferon-\textgreek{a} suppresses bladder cancer through activation of PDE4D. In: Journal of Experimental {\&} Clinical Cancer Research, 37, 2018,
2018Adenubi, Olubukola T. and {Ali Abdalla}, Muna and Ahmed, Aroke S. and Njoya, Emmanuel M. and McGaw, Lyndy J. and Eloff, Jacobus N. and Naidoo, Vinny: Isolation and characterization of two acaricidal compounds from Calpurnia aurea subsp. aurea (Fabaceae) leaf extract. In: Experimental and Applied Acarology, 75, 2018, 345--354
2018Jouda, Jean-Bosco and {Mfotie Njoya}, Emmanuel and Mbazoa, C{\'e}line Djama and Zhou, Zongyuan and {Meli Lannang}, Alain and Wandji, Jean and Shiono, Yoshihito and Wang, Fei: Lambertellin from Pycnoporus sanguineus MUCL 51321 and its anti-inflammatory effect via modulation of MAPK and NF-\textgreek{k}B signaling pathways. In: Bioorganic Chemistry, 80, 2018, 216--222
2018Mehrbod, Parvaneh and Abdalla, Muna A. and Njoya, Emmanuel M. and Ahmed, Aroke S. and Fotouhi, Fatemeh and Farahmand, Behrokh and Gado, Dorcas A. and Tabatabaian, Mansoureh and Fasanmi, Olubunmi G. and Eloff, Jacobus N. and McGaw, Lyndy J. and Fasina, Folorunso O.: South African medicinal plant extracts active against influenza A virus. In: BMC Complementary and Alternative Medicine, 18, 2018,
2018Motlhatlego, K. E. and {Mfotie Njoya}, E. and Abdalla, M. A. and Eloff, J. N. and McGaw, L. J.: The potential use of leaf extracts of two Newtonia (Fabaceae) species to treat diarrhoea. In: South African Journal of Botany, 116, 2018, 25--33
2018Adawaren, Emmanuel Oluwasegun and Mukandiwa, Lilian and Njoya, Emmanuel Mfotie and Bekker, Lizette and Duncan, Neil and Naidoo, Vinny: The use of liver slices from the Cape vulture ( Gyps coprotheres ) to better understand the role of liver toxicity of non-steroidal anti-inflammatory drugs (NSAIDs) in vultures. In: Environmental Toxicology and Pharmacology, 62, 2018, 147--155
2017{Mfotie Njoya}, Emmanuel and Munvera, Aristide Mfifen and Mkounga, Pierre and Nkengfack, Augustin Ephrem and McGaw, Lyndy Joy: Phytochemical analysis with free radical scavenging, nitric oxide inhibition and antiproliferative activity of Sarcocephalus pobeguinii extracts. In: BMC Complementary and Alternative Medicine, 17, 2017,
2014{Mfotie Njoya}, Emmanuel and Weber, Christian and Hernandez-Cuevas, Nora Adriana and Hon, Chung-Chau and Janin, Yves and Kamini, Melanie F. G. and Moundipa, Paul F. and Guill{\'e}n, Nancy: Bioassay-Guided Fractionation of Extracts from Codiaeum variegatum against Entamoeba histolytica Discovers Compounds That Modify Expression of Ceramide Biosynthesis Related Genes. In: PLoS Neglected Tropical Diseases, 8, 2014, e2607
2014{Mfotie Njoya}, Emmanuel and Moundipa, Paul F. and Stopper, Helga: in vitro genotoxic and mutagenic evaluation of the aqueous extract of Codiaeum variegatum and its amoebicidal sub-fraction. In: Journal of Ethnopharmacology, 155, 2014, 823--829