Dr. Sergio Romero Romero

Profile

Academic positionAssociate Professor, Senior Lecturer, Reader
Research fieldsBiochemistry,Structural Biology
KeywordsProtein Evolution, Protein Engineering, Protein Design, Protein Folding, Ligand binding

Current contact address

CountryMexico
CityCiudad de Mexico
InstitutionUniversidad Nacional Autonoma de Mexico (UNAM)
InstituteInstituto de Fisiologia Celular
Homepagehttps://www.ifc.unam.mx/investigadores/sergio-romero

Host during sponsorship

Prof. Dr. Birte HöckerLehrstuhl für Biochemie, Universität Bayreuth, Bayreuth
Start of initial sponsorship01/10/2020

Programme(s)

2020Humboldt Research Fellowship Programme for Postdocs

Publications (partial selection)

2021Romero-Romero, Sergio and Kordes, Sina and Michel, Florian and Hocker, Birte: Evolution, folding, and design of TIM barrels and related proteins. In: Current Opinion in Structural Biology, 68, 2021, 94--104
2021Romero-Romero, Sergio and Costas, Miguel and Manzano, Daniel-Adriano Silva and Kordes, Sina and Rojas-Ortega, Erendira and Tapia, Cinthya and Guerra, Yasel and Shanmugaratnam, Sooruban and Rodriguez-Romero, Adela and Baker, David and Fernandez-Velasco, Daniel: The stability landscape of de novo TIM barrels explored by a modular design approach. In: Journal of Molecular Biology, 2021, 167153
2020Garcia-Garcia, Jorge Donato and Sanchez-Thomas, Rosina and Saavedra, Emma and Fernandez-Velasco, Daniel Alejandro and Romero-Romero, Sergio and Casanova-Figueroa, Karla I and Mendoza-Cozatl, David G and Moreno-Sanchez, Rafael: Mapping the metal-catalytic site of a zinc-activated phytochelatin synthase. In: Algal Research, 47, 2020, 101890
2020Vergara, Renan and Romero-Romero, Sergio and Velazquez-Lopez, Isabel and Espinoza-Perez, Georgina and Rodriguez-Hernandez, Annia and Pulido, Nancy O and Sosa-Peinado, Alejandro and Rodriguez-Romero, Adela and Fernandez-Velasco, D Alejandro: The interplay of protein-ligand and water-mediated interactions shape affinity and selectivity in the LAO binding protein. In: The FEBS Journal, 287, 2020, 763--782
2019Cristobal-Mondragon, Gema R and Lara-Chacon, Barbara and Santiago, Angel and De-la-Rosa, Victor and Gonzalez-Gonzalez, Rogelio and Muniz-Luna, Julio A and Ladron-de-Guevara, Ernesto and Romero-Romero, Sergio and Rangel-Yescas, Gisela E and Fernandez Velasco, D Alejandro and others: FRET-based analysis and molecular modeling of the human GPN-loop GTP ases 1 and 3 heterodimer unveils a dominant-negative protein complex. In: The FEBS Journal, 286, 2019, 4797--4818
2019Castro-Torres, Eduardo and Jimenez-Sandoval, Pedro and Romero-Romero, Sergio and Fuentes-Pascacio, Alma and Lopez-Castillo, Laura M and Diaz-Quezada, Corina and Fernandez-Velasco, D Alejandro and Torres-Larios, Alfredo and Brieba, Luis G: Structural basis for the modulation of plant cytosolic triosephosphate isomerase activity by mimicry of redox-based modifications. In: The Plant Journal, 99, 2019, 950--964
2019Balleza, Daniel and Rosas, Mario E. and Romero-Romero, Sergio: Voltage vs. Ligand I: Structural basis of the intrinsic flexibility of S3 segment and its significance in ion channel activation. In: Channels, 13, 2019, 455--476
2019Romero-Romero, Sergio and Martinez-Delgado, Gustavo and Balleza, Daniel: Voltage vs. Ligand II: Structural insights of the intrinsic flexibility in cyclic nucleotide-gated channels. In: Channels, 13, 2019, 382--399
2018Quezada, Andrea G and Cabrera, Nallely and Pineiro, Angel and Diaz-Salazar, A Jessica and Diaz-Mazariegos, Selma and Romero-Romero, Sergio and Perez-Montfort, Ruy and Costas, Miguel: A strategy based on thermal flexibility to design triosephosphate isomerase proteins with increased or decreased kinetic stability. In: Biochemical and biophysical research communications, 503, 2018, 3017--3022
2018Barrios-Villa, Edwin and Cortes-Cortes, Gerardo and Zarain, Patricia Lozano and Romero-Romero, Sergio and Flores, Norarizbeth Lara and Estepa, Vanesa and Somalo, Sergio and Torres, Carmen and del Carmen Rocha-Gracia, Rosa: Characterization of extended-spectrum and CMY-2 B-lactamases, and associated virulence genes in Escherichia coli from food of animal origin in Mexico. In: British Food Journal, 120, 2018, 1457--1473
2018Romero-Romero, Sergio and Fernandez-Velasco, D Alejandro and Costas, Miguel: Donde la termodinamica y las proteinas se encuentran. In: Educacion quimica, 29, 2018, 18--21
2018Romero-Romero, Sergio and Fernandez-Velasco, D Alejandro and Costas, Miguel: Estabilidad termodinamica de proteinas. In: Educacion quimica, 29, 2018, 3--17
2018Velazquez-Lopez, Isabel and Valdes-Garcia, Gilberto and Romero, Sergio Romero and Martinez, Roberto Maya and Leal-Cervantes, Ana I and Costas, Miguel and Sanchez-Lopez, Rosana and Amero, Carlos and Pastor, Nina and Velasco, D Alejandro Fernandez: Localized conformational changes trigger the pH-induced fibrillogenesis of an amyloidogenic lambda light chain protein. In: Biochimica et Biophysica Acta (BBA)-General Subjects, 1862, 2018, 1656--1666
2018Romero-Romero, Sergio and Becerril-Sesin, Luis A and Costas, Miguel and Rodriguez-Romero, Adela and Fernandez-Velasco, D Alejandro: Structure and conformational stability of the triosephosphate isomerase from Zea mays. Comparison with the chemical unfolding pathways of other eukaryotic TIMs. In: Archives of biochemistry and biophysics, 658, 2018, 66--76
2017Romero-Romero, Sergio and Gomez Lagunas, Froylan and Balleza, Daniel: Side chain flexibility and coupling between the S4-S5 linker and the TRP domain in thermo-sensitive TRP channels: Insights from protein modeling. In: Proteins: Structure, Function, and Bioinformatics, 85, 2017, 630--646
2015Romero-Romero, Sergio and Costas, Miguel and Rodriguez-Romero, Adela and Fernandez-Velasco, D Alejandro: Reversibility and two state behaviour in the thermal unfolding of oligomeric TIM barrel proteins. In: Physical Chemistry Chemical Physics, 17, 2015, 20699--20714
2012R. C. Rocha-Gracia, S. Romero-Romero, M. A. Mondragon-Salinas, P. Lozano-Zarain, Y. Martinez-Laguna: Haemophilus influenzae. Benemerita Universidad Autonoma de Puebla, 2012
2010Rocha-Gracia, Rosa and Ruiz, Elena and Romero-Romero, Sergio and Lozano-Zarain, Patricia and Somalo, Sergio and Palacios-Hernandez, J Martin and Caballero-Torres, Paula and Torres, Carmen: Detection of the plasmid-borne quinolone resistance determinant qepA1 in a CTX-M-15-producing Escherichia coli strain from Mexico. In: Journal of antimicrobial chemotherapy, 65, 2010, 169--171
2009H. M. M. P. Arenas, I. Garcia-Lopez, M. Pacheco-Blanco, S. Romero-Romero, J. A., Valencia-de Lima: Uso adecuado e irracional de los antibioticos. Benemerita Universidad Autonoma de Puebla, 2009
2009R. C. Rocha-Gracia, S. Romero-Romero, P. Lozano-Zarain, Y. Martinez-Laguna, E. Ruiz-Ruiz: Uso de antibioticos como promotores del crecimiento animal y sus consecuencias en la resistencia bacteriana y salud humana. Benemerita Universidad Autonoma de Puebla, 2009