Dr. Rory Little

Profile

Academic positionPost Doc
Research fieldsBioorganic and Biological Chemistry,Natural Product Chemistry,Biochemistry
KeywordsTranscriptomics, Microbiology, Biosynthesis, Structural Biology, Enzyme mechanisms

Current contact address

CountryNew Zealand
CityWellington
InstitutionVictoria University of Wellington
InstituteSchool of Biological Sciences

Host during sponsorship

Prof. Dr. Christian HertweckLeibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut, Jena
Start of initial sponsorship01/03/2021

Programme(s)

2020Humboldt Research Fellowship Programme for Postdocs

Publications (partial selection)

2022Rory Little, Felix Trottmann, Miriam Preissler, and Christian Hertweck: An intramodular thioesterase domain catalyses chain release in the biosynthesis of a cytotoxic virulence factor. In: RSC Chem. Biol., 3, 2022,
2022Rory F. Little and Christian Hertweck Chain release mechanisms in polyketide and non-ribosomal peptide biosynthesis. In: Natural Product Reports, 39, 2022, 163-205
2020S. P. Niehs, J. Kumpfmüller, B. Dose, R. F. Little, K. Ishida, L. V. Flórez, M. Kaltenpoth, C. Hertweck: Insect-Associated Bacteria Assemble the Antifungal Butenolide Gladiofungin by Non-Canonical Polyketide Chain Termination. In: Angew. Chem. Int. Ed., 59, 2020, 23122