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Profile
| Academic position | Full Professor |
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| Research fields | Biophysics,Cell Biology,Biophysical Chemistry |
| Keywords | Electron Microscopy, image processing, macromolecular complexes, three-dimensional structure |
Current contact address
| Country | United States of America |
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| City | Bethesda |
| Institution | National Institutes of Health (NIH) |
| Institute | Laboratory of Structural Biology |
Host during sponsorship
| Prof. Dr. Wolfgang Baumeister | Abteilung Molekulare Strukturbiologie, Max-Planck-Institut für Biochemie, Martinsried |
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| Prof. Dr. Wolfgang Baumeister | Abteilung Molekulare Strukturbiologie, Max-Planck-Institut für Biochemie, Planegg-Martinsried |
| Start of initial sponsorship | 01/11/2000 |
Programme(s)
| 2000 | Humboldt Research Award Programme |
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Nominator's project description
| The award is made in recognition of pioneering contributions to the analysis of regulatory conformational changes in macromolecular assemblies. These studies have featured creative innovations in the use of electron microscopy and image processing, combined with other biochemical, biophysical and genetic approaches. They have yielded fundamental new insights into the processes of virus assembly and maturation, amyloid filament formation by prions, structure-function relationships of intermediate filaments and energy-dependent proteases. Joint Project: Structural analysis of viruses, in particular Herpes simplex virus, by cryoelectron tomography. |
Publications (partial selection)
| 2003 | Alasdair Colin Steven and others: Three-dimensional Structure of Herpes Simplex Virus from Cryo-electron Tomography. In: Biophysical Chemistry, 2003, 577-591 |
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