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Profile
| Academic position | Full Professor |
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| Research fields | Immunology |
| Keywords | Cancer, carbohydrates, mannan-binding, lectin, complement |
Current contact address
| Country | Denmark |
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| City | Aarhus |
| Institution | Aarhus University |
| Institute | Department of Medical Microbiology and Immunology |
Host during sponsorship
| Prof. Dr. Daniela Männel | Institut für Immunologie, Universität Regensburg, Regensburg |
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| Prof. Dr. Ferdinand Hofstädter | Institut für Pathologie, Universität Regensburg, Regensburg |
| Start of initial sponsorship | 01/07/2003 |
Programme(s)
| 2003 | Humboldt Research Award Programme |
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Nominator's project description
| The pioneering scientific contribution of Professor Jensenius is the molecular characterization of a new anti-micorbial system in innate immune defense. This so-called lectin pathway of complement activations is initiated by serum molecules recognizing sugars displayed on microorganisms but also on tumor cells. Genetically determined deficiency in theses defense molecules predisposes for infections. Since the may also play an important role in tumor defense we will investigate whether these molecules could present a therapeutic modality for tumor patients with such deficiency. |
Publications (partial selection)
| 2004 | Jens Christian Jensenius et al: Involvement of the Lectin Pathway of Complement Activation in Antimicrobial Immune Defense during Experimental Septic Peritonitis. In: Infection and Immunity, 2004, 5247-5252 |
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