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Profil
| Derzeitige Stellung | Professor W-3 und Äquivalente |
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| Fachgebiet | Immunologie |
| Keywords | Cancer, carbohydrates, mannan-binding, lectin, complement |
Aktuelle Kontaktadresse
| Land | Dänemark |
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| Ort | Aarhus |
| Universität/Institution | Aarhus University |
| Institut/Abteilung | Department of Medical Microbiology and Immunology |
Gastgeber*innen während der Förderung
| Prof. Dr. Daniela Männel | Institut für Immunologie, Universität Regensburg, Regensburg |
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| Prof. Dr. Ferdinand Hofstädter | Institut für Pathologie, Universität Regensburg, Regensburg |
| Beginn der ersten Förderung | 01.07.2003 |
Programm(e)
| 2003 | Forschungspreis-Programm auf Gegenseitigkeit für Wissenschaftler*innen aus dem Ausland |
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Projektbeschreibung der*des Nominierenden
| The pioneering scientific contribution of Professor Jensenius is the molecular characterization of a new anti-micorbial system in innate immune defense. This so-called lectin pathway of complement activations is initiated by serum molecules recognizing sugars displayed on microorganisms but also on tumor cells. Genetically determined deficiency in theses defense molecules predisposes for infections. Since the may also play an important role in tumor defense we will investigate whether these molecules could present a therapeutic modality for tumor patients with such deficiency. |
Publikationen (Auswahl)
| 2004 | Jens Christian Jensenius et al: Involvement of the Lectin Pathway of Complement Activation in Antimicrobial Immune Defense during Experimental Septic Peritonitis. In: Infection and Immunity, 2004, 5247-5252 |
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