Prof. Dr. Mordecai P. Blaustein

Profil

Derzeitige StellungProfessor W-3 und Äquivalente
FachgebietAnatomie und Physiologie
KeywordsSodium transport, Calcium transport

Aktuelle Kontaktadresse

LandUSA
OrtBaltimore
Universität/InstitutionUniversity of Maryland, Baltimore
Institut/AbteilungSchool of Medicine, Department of Physiology

Gastgeber*innen während der Förderung

Prof. Dr. Ernst BambergMax-Planck-Institut für Biophysik, Frankfurt am Main
Prof. Dr. Karl Julius UllrichMax-Planck-Institut für Biophysik, Frankfurt am Main
Beginn der ersten Förderung16.04.1993

Programm(e)

1992Humboldt-Forschungspreis-Programm für Naturwissenschaftler*innen aus den USA

Projektbeschreibung der*des Nominierenden

Professor Blaustein is one of the leading physiologists and biophysicists in the field of hypertension. He developed the hypothesis on the molecular mechanism of the hypertension which includes the existence of the endogenous adrenocortical hormone ouabain, and the inhibition of the sodium pump by the hormone in vascular smooth muscle cells. Consequently, the rise of internal sodium causes via the sodium-calcium exchanger an elevated calcium ion level leading to the hypertension producing vasoconstriction. During his numerous research stays in Germany, Professor Blaustein studied the molecular mechanism of the sodium/calcium exchanger.