Prof. Dr. Hirobumi Yamamoto

Profil

Derzeitige StellungProfessor W-3 und Äquivalente
FachgebietPharmazie,Biochemie und Biophysik der Pflanzen
KeywordsLithospermum erythrorhizon, plant cell cultures, shikonin production, enzymes, biosynthesis

Aktuelle Kontaktadresse

LandJapan
OrtGunma
Universität/InstitutionToyo University
Institut/AbteilungFaculty of Sciences

Gastgeber*innen während der Förderung

Prof. Dr. Lutz HeideAbteilung Pharmazeutische Biologie, Eberhard Karls Universität Tübingen, Tübingen
Beginn der ersten Förderung01.08.1998

Programm(e)

1997Humboldt-Forschungsstipendien-Programm

Publikationen (Auswahl)

2008Kanako Sasaki, Kouji Mito, Kazuaki Ohara, Hirobumi Yamamoto, Kazufumi Yazaki: Cloning and Characterization of Naringenin 8-Prenyltransferase, a Flavonoid-Specific Prenyltransferase of Sophora flavescens. In: Plant Physiology, 2008, 1075-1084
2007Nobuyoshi Sato, Minoru Uehara, Koichiro Shimomura, Hirobumi Yamamoto, Kenichi Kamijo: Outlier Rejection in Massive Trace Element Data for Geographical Origin Identification System of Vegetables. In: Journal of Networks, 2007, 61-68
2006Nobuyoshi Sato, Minoru Uehara, Koichiro Shimomura, Hirobumi Yamamoto, Kenichi Kamijo: Efficient Retrieval on Dense Vector by Similarity Preserve Hash in Vegetable Geographical Origin Identification System. In: International Journal of Computer Science and Network Security, 2006, 227-235
2006Rahnab L.-ur, Kitamura Y., Yamaguchi J., Murai M., Akiyama K., Yamamoto H., Muranaka T., Ikenaga T.: Exogenous plant H6H but not bacterial HCHL gene is expressed in Duboisia leichhardtii hairy roots and affect tropane alkaloid production. In: Emzyme and Microbial Technology, 2006, 1183-1189
2005Sato N., Uehara M., Tamaoka J., Shimomura K., Yamamoto H., Kamijo K.: A Distributed Geographical Origin Identification System for Agricultural Products by Trace Element Compositions. In: International J. Computer Science and Network Security, 2005, 55-63
2005Taguchi G., Shitchi Y., Shirasawa S., Yamamoto H., Hayashida N.: Molecular cloning, characterization, and downregulation of an acyltransferase that catalyzes the malonylation of flavonoid and naphthol glucosides in tobacco cells. In: The Plant Journal, 2005, 481-491
2004Ohara K., Kokado Y., Yamamoto H., Sato F., Yazaki K: Engineering of ubiquinone biosynthesis using the yeast coq2 gene confers oxidative stress tolerance in transgenic tobacco. In: The Plant Journal, 2004, 734-743
2004Yamamoto H., Kuribayashi H., Seshima Y., Zhao P., Kouno I., Taguchi G., Shimomura K.: Metabolism of administered (2RS)-naringenin in flavonoid-producing cultured cells of Sophora flavescens. In: Plant Biotechnology, 2004, 355-359
2004Zhao P., Zhang Y.-G., Yamamoto H., Yang C.-G.: Recent advance on the chemistry, bioactivity and biosynthesis of prenylated flavonoids from Sophora flacescens. In: Tianran Chanwu Yanjiu Yu Kaifa, 2004, 172-178
2004P. Zhao, Y. Iwamoto, I. Kouno, Y. Egami, H. Yamamoto: Stimulating the production of homoisoflavonoids in cell suspension cultures of Caesalpinia pulcherrima using cork tissue. In: Phytochemistry , 2004, 2455-2461
2003P. Zhao, K. Inoue, I. Kouno, H. Yamamoto: Characterization of leachianone G 2'' -dimethylallyltransferase, a novel prenyl side-chain elongation enzyme for the formation of the lavandulyl group of sophoraflavanone G in Sophora flavescens Ait. cell suspension cultures. In: Plant Physiology, 2003, 1306-1313
2003G. Taguchi, T. Ubukata, N. Hayashida, H. Yamamoto, M. Okazaki: Cloning and characterization of a glucosyltransferase that reacts on 7-hydroxyl group of flavonol and 3-hydroxyl group of coumarin from tobacco cells. In: Arch. Biochem. Biophys., 2003, 95-102
2003P. Zhao, C. Hamada, K. Inoue, H. Yamamoto: Efficient production and capture of 8-prenylnaringenin and leachianone G ¿ biosynthetic intermediates of sophoraflavanone G ¿ by the addition of cork tissue to cell suspension cultures of Sophora flavescens. In: Phytochemistry, 2003, 1093-1099
2003H. Yamamoto, M. Hori, H. Kuwajima, K. Inoue: Formation of benzoquinol moiety in cornoside by salidroside mono-oxygenase, a cytochrome P450 enzyme, from Abeliophyllum distichum cell suspension cultures. In: Planta, 2003, 432-436
2003K. Terasaka, K. Sakai, F. Sato, H. Yamamoto, K. Yazaki: Thalictrum minus cell cultures and ABC-like transporter. In: Phytochemistry, 2003, 483-489
2002H. Yamamoto, M. Sha, Y. Kitamura, M. Yamaguchi, N. Katano, K. Inoue: Iridoid biosynthesis: 7-deoxyloganetic acid 1-O-glucosyltransferase in cultured Lonicera japonica cells. In: Plant Biotechnology, 2002, 295-301
2002H. Yamamoto, P. Zhao, K. Inoue: Origin of two isoprenoid units in a lavandulyl moiety of sophoraflavanone G from Sophora flavescens cultured cells. In: Phytochemistry, 2002, 263-267
2002H. Yamamoto, P. Zhao, K. Yazaki, K. Inoue: Regulation of lithospermic acid B and shikonin production in Lithospermum erythrorhizon cell suspension cultures. In: Chemical & Pharmaceutical Bulletin, 2002, 1086-1090
2001H. Yamamoto, A. Yatou, K. Yazaki, H. Hayashi, G. Taguchi, K. Inoue: Increases of secondary metabolite production in various plant cell cultures by co-cultivation with cork. In: Bioscience, Biotechnology and Biochemistry, 2001, 853-860
2001N. Katano, H. Yamamoto, R. Iio, K. Inoue: 7-Deoxyloganin 7-hydroxylase in Lonicera japonica cell cultures. . In: Phytochemistry, 2001, 53-58
2001H. Yamamoto, A. Yatou, K. Inoue: 8-Dimethylallylnaringenin 2¿-hydroxylase, the crucial cytochrome P450 monooxygenase for lavandulylated flavanone formation in Sophora flavescens cultured cells. In: Phytochemistry, 2001, 671-676
2001H. Yamamoto, A. Yatou, K. Yazaki, H. Hayashi, G. Taguchi, K. Inoue: Increases of secondary metabolite production in various plant cell cultures by co-cultivation with cork. In: Bioscience, Biotechnology and Biochemistry, 2001, 853-860
2001A.B. Kirakosyan, R.R. Vardapetyan, A.G. Charchoglyan, H. Yamamoto, H. Hayashi, K. Inoue: The effect of cork pieces on pseudohypericin production in cells of Hypericum perforantum shoots. In: Russian Journal of Plant Physiology, 2001, 816-819
2000H. Yamamoto, M. Senda, K. Inoue: Flavanone 8-dimethylallyltransferase in Sophora flavescens cell suspension cultures. In: Phytochemistry, 2000, 649-655
2000H. Yamamoto, K. Inoue, S.-M. Li, L. Heide: Geranylhydroquinone 3¿-hydroxylase, a cytochrome P-450 monooxygenase from Lithospermum erythrorhizon cell suspension cultures. In: Planta, 2000, 312-317
2000H. Hayashi, N. Hosono, M. Kondo, N. Hiraoka, Y. Ikeshiro, M. Shibano, G. Kusano, H. Yamamoto, T. Tanaka K. Inoue: Phylogenetic relationship of six Glycyrrhiza species based on rbcL sequences and chemical constituents. In: Biological & Pharmaceutical Bulletin, 2000, 602-606
2000H. Yamamoto, K. Yazaki, K. Inoue: Production of caffeic acid oligomers in Lithospermum erythrorhizon cell suspension cultures. In: Phytochemistry, 2000, 651-657
2000H. Yamamoto, N. Katano, A. Ooi, K. Inoue: Secologanin synthase which catalyzes the oxidative cleavage of loganin into secologanin is a cytochrome P-450. In: Phytochemistry, 2000, 7-12
2000H. Yamamoto, K. Yazaki, K. Inoue: Simultaneous analysis of shikimate-derived secondary metabolites in Lithospermum erythrorhizon cell suspension cultures by high-performance liquid chromatography. In: Journal of Chromatography B: Biomedical Sciences and Applications, 2000, 3-15