Dr. Lawrence A. D. Williams

Profil

Derzeitige StellungProfessor W-1 und Äquivalente
FachgebietBiochemie und Biophysik der Pflanzen,Systematik und Morphologie der Tiere,Naturstoffchemie
Keywordsagrochemical, anti-cellular, toxicology, natural products, medicinal

Aktuelle Kontaktadresse

LandJamaika
OrtKingston 6
Universität/InstitutionScientific Research Council

Gastgeber*innen während der Förderung

Prof. Dr. Wolfgang KrausInstitut für Chemie, Universität Hohenheim, Stuttgart
Prof. Dr. Harald RösnerInstitut für Zoologie, Universität Hohenheim, Stuttgart
Beginn der ersten Förderung01.06.1999

Programm(e)

1998Georg Forster-Forschungsstipendien-Programm

Publikationen (Auswahl)

2007Lawrence A. D. Williams, H. Rosner, HG. Levy, EN. Barton A critical review of the therapeutic potential of dibenzyl trisulphide isolated from Petiveria alliacea L (Guinea hen weed, anamu.). In: West Indian Medical Journal, 2007, 17-21
2007H. Leutbecher, Lawrence A. D. Williams, H. Rosner, U. Beifuss: Efficient synthesis of 7-methyl-2H,5H-pyrano [4,3-b] pyran-5-ones and evaluation of their in vitro anti-proliferative/cytotoxic activities . In: Bioorganic and Medicinal Chemistry Letters, 2007, 978-982
2007Lawrence A. D. Williams, J. Conrad, B. Vogler, H. Rosner, RBR. Porter, W. Setzer, EN. Barton, HG. Levy, S. Mika, I. Klaiber, JP. Nkurunziza, W. Kraus: In vitro anti-proliferation / cytotoxic acitivity of epingaione and its derivatives on the human SH-SY5Y neuroblastoma and TE-671 Sarcoma Cells. In: West Indian Medical Journal , 2007, 5-10
2006Lawrence A. D. Williams, S. L. Hibbert, R. B. R. Porter, Y. A. Bailey-Shaw, C. E. Green: Jamaican plants with in vitro anti-oxidant activity. In: Lawrence A. D. Williams, Biologically active natural products for the 21st Century. SignPost, 2006. 1-12
2006P. C. Facey, R. B. R. Porter, Lawrence A. D. Williams: The Chemical composition and isecticidal activity of the essential oils from Jamaican Hyptis capitata Jacq. . In: Lawrence A. D. Williams, Biologically active natural products for the 21st Century . SignPost, 2006. 13-19
2005P. C. Facey, B. R. Porter, P. B. Reese, Lawrence A. D. Williams: Biological activity and chemical composition of the essential oil from Jamaican Hyptis verticillata . In: Jacq. Journal of Agricultural and Food Chemistry, 2005, 4774-4777
2004Lawrence A. D. Williams, H. Rosner, W. Moller, W. Kraus: Anti-proliferation/cytotoxic action of Dibenzyl trisulphide, a secondary metabolite of Petiveria alliacea . In: Jamaican Journal of Science an Technology, 2004, 54-60
2004Lawrence A. D. Williams, H. Rösner, W. Möller, J. Conrad, J.P. Nkurunziza, W. Kraus: In Vitro Anti-Proliferation/Cytotoxic Activity of Sicty Natural Products on the Human SH-SY5Y Neuroblastoma Cells with Specific Reference to Dibenzyl Trisulphide. In: West Indian Med J, 2004, 208-219
2003Lawrence A. D. Williams: A sulfonic anhydride derivative from dibenzyl trisulphide with argochemical activities. In: Chemosphere, 2003, 701-706
2003Lawrence A. D. Williams, E. Vesques, W. Reid, R. Porter, W. Kraus: Biological activities of an extract from Cleome viscosa L. (Capparaceae). In: Naturwissenschaften , 2003, 468-472
2003Lawrence A. D. Williams, H. Rösner, W. Möller, E. Merisor, W. Kraus: In vitro antiproliferation/cytototoxic activity of cantharidin (Spanish fly) and related derivatives. In: West Indian Medical Journal, 2003, 10-13
2002Lawrence A. D. Williams, E. A. Vasquez, P. P. Milan, C. Zebitz, W. Kraus: In vitro anti-inflammatory and anti-microbial activities of phenylpropanoids from Piper betle Piperaceae. In: A. Rauter, E. Aranjo, F. Sales, J. Justino, S. P. Santos, Natural Products in the New Millenium: Prospects and Industrial Application. Kluwer Academic Publisher, 2002.
2002Lawrence A. D. Williams, H. Rösner, J. Conrad, W. Möller, U. Beifuss, K. Chiba, J. P. Nkurunziza, W. Kraus: Selected secondary metabolites from the phytolaccaceae and their biological/pharmaceutical significance. In: Recent Res. Devel. Phytochem, 2002, 13-68
2001W. Kraus. E. A. Vasquez, Lawrence A. D. Williams: Bioassay-guidd isolation of active compounds in plant extracts: Bioassay system. Proc.. In: University of the West Indies, Trends and Needs. Campus, 2001. 101-106
2001Lawrence A. D. Williams, H. Rösner, A. Jung, W. Kraus: Disassembly and microtubules and inhibition of neurite outgrowth, neuroblastoma cell proliferation, and MAP kinase tyrosine dephosphorylation by dibenzyl trisulphide. In: Biochimica et Biophysica Acta, 2001, 166-177
2001Lawrence A. D. Williams, R. C. Howell, R. Young, I. A. Kahwa: Neuropharmacological actions of some binuclear lanthanide (III) complexes. In: Comparative Biochemistry and Physiology, Part C, 2001, 121-127
2001A. Mansigh, Lawrence A. D. Williams: Pesticide potential of tropical plants-VIII: acute toxicity and inhibition of oogenesis in the ticks Boophilus microplus Canst. and Amblyomma cajennense Fab. by extracts of Azadirachta indica A. Juss and Artocapus altilis Parks. In: University of the West Indies, Trends and Needs. Mona Campus, 2001. 231-239
2000Lawrence A. D. Williams, D. O. Collins, W. A. Gallimore, W. F. Reynolds, P. B. Reese: New skeletial sesquiterpenoid, Caprariolides A-D from Capraria biflora and their insecticidal activity. In: Journal of Natural Product, 2000, 1515-1518