Prof. Dr. Saeid Bouzari

Profil

Derzeitige StellungProfessor W-3 und Äquivalente
FachgebietStoffwechselphysiologie, Biochemie und Genetik der Mikroorganismen
KeywordsEscherichia coli, diarrhoea, genomic, EHEC, EAEC, EPEC, microbial pathogenesis, virulence factors

Aktuelle Kontaktadresse

LandIran
OrtTehran
Universität/InstitutionInstitut Pasteur Iran
Institut/AbteilungMolecular Biology Unit

Gastgeber*innen während der Förderung

Prof. Dr. Trinad ChakrabortyInstitut für Medizinische Mikrobiologie, Universitätsklinikum Giessen und Marburg (UKGM), Gießen
Beginn der ersten Förderung01.09.2001

Programm(e)

2001Georg Forster-Forschungsstipendien-Programm

Publikationen (Auswahl)

2017Miri ST, Dashti A, Mostaan S, Kazemi F, Bouzari S.: Identification of different Escherichia coli pathotypes in north and north-west provinces of Iran. . In: Iran J Microbiol, 2017, 33--37.
2017Valiyari S, Salami M, Mahdian R, Shokrgozar MA, Oloomi M, Mohammadi Farsani A, Bouzari S.: sIL-24 peptide, a human interleukin-24 isoform, induces mitochondrial-mediated apoptosis in human cancer cells. . In: Cancer Chemother Pharmacol, 2017,
2017Sarshar S, Brandt S, Asadi Karam MR, Habibi M, Bouzari S, Lechtenberg M, Dobrindt U, Qin X, Goycoolea FM, Hensel A.: Aqueous extract from Orthosiphon stamineus leaves prevents bladder and kidney infection in mice. . In: Phytomedicine, 2017, 1--9.
2017Amraee M, Oloomi M, Yavari A, Bouzari S.: DNA aptamer identification and characterization for E. coli O157 detection using cell based SELEX method. . Aug ;536:. . In: Anal Biochem, 2017, 36--44
2017Afrough P, Bouzari S, Mousavi SF, Asadi Karam MR, Vaziri F, Fateh A, Behrouzi A, Malekan M, Siadat SD.: Evaluation of immunological responses to recombinant Porin A protein (rPoA) from native strains of Neisseria meningitidis serogroups A and B using OMV as an adjuvant in BALB/c mice. doi: 10.1016/j.micpath.2017.09.038. [Epub ahead of prin. In: Microb Pathog. Sep 20;, 2017, 209.--214
2017Habibi M, Asadi Karam MR, Bouzari S.: Evaluation of prevalence, immunogenicity and efficacy of FyuA iron receptor in uropathogenic Escherichia coli isolates as a vaccine target against urinary tract infection. . In: Microb Pathog., 2017, ;477--483.
2017Javadi M, Oloomi M, Bouzari S.: In Silico Signature Prediction Modeling in Cytolethal Distending Toxin-Producing Escherichia coli Strains. . In: Genomics Inform, 2017, 69--80.
2017Golshani M, Rafati S, Nejati-Moheimani M, Pourabdi S, Arsang A, Bouzari S.: Protein/Protein, DNA/DNA and DNA/Protein based vaccination strategies using truncated Omp2b against Brucella infection in BALB/c Mice. . In: Int J Med Microbiol, 2017, 249--256
2017Behrouzi A, Bouzari S, Vaziri F, Fateh A, Afrough P, Vijeh Motlagh AD, Siadat SD.: Recombinant truncated E protein as a new vaccine candidate against nontypeable H. influenzae: Its expression and immunogenic evaluation. . In: Microb Pathog., 2017, 431--438.
2016Golshani M, Rafati S, Nejati-Moheimani M, Ghasemian M, Bouzari S.: 14. Comparison of potential protection conferred by three immunization strategies (protein/protein, DNA/DNA, and DNA/protein) against Brucella infection using Omp2b in BALB/c Mice. . Dec 25;:.. In: Vet Microbiol, 2016, 47--52
2016Darbandi A, Owlia P, Bouzari S, Saderi H.: Diarrheagenic Escherichia coli pathotypes frequency in Khuzestan province of Iran. . Dec;. In: Iran J Microbiol, 2016, 352--358.
2016Tabasi M, Karam MR, Habibi M, Mostafavi E, Bouzari S.: Genotypic Characterization of Virulence Factors in Escherichia coli Isolated from Patients with Acute Cystitis, Pyelonephritis and Asymptomatic Bacteriuria. . In: J Clin Diagn Res, 2016,
2016Golshani M, Oloomi M, Bouzari S.: In silico analysis of Shiga toxins (Stxs) to identify new potential vaccine targets for Shiga toxin-producing Escherichia coli. . In: In Silico Pharmacol, 2016,
2016Asadi Karam MR, Habibi M, Bouzari S.: Use of flagellin and cholera toxin as adjuvants in intranasal vaccination of mice to enhance protective immune responses against uropathogenic Escherichia coli antigens. . In: Biologicals, 2016, 378--86.
2008Bergstrom KS, Guttman JA, Rumi M, Ma C, Bouzari S, Khan MA, Gibson DL, Vogl AW, Vallance BA . Modulations of intestinal goblet cell function during infection by an attaching and effacing bacterial pathogen.. In: Infect. Immun, 2008, 796-811
2008Oloomi M, Bouzari S, Ajdary S, . Immune response of mice immunized with active recombinant Shiga Toxin and its derivatives. . In: Iran J Allergy Asthema Immunol, 2008, 53-60
2008Mohammed A. Khan, Saeid Bouzari,1 Caixia Ma, Carrie M. Rosenberger, Kirk S. B. Bergstrom, Deanna L. Gibson, Theodore S. Steiner, and Bruce A. Vallance Flagellin-dependent and -independent inflammatory responses following infection by enteropathogenic Escherichia coli (EPEC) and Citrobacter rodentium. . In: Infect Immun, 2008, 1410 -1422
2008Habibi Roudkenar M, Bouzari, S., Kuwahara,Y., Mohammadi Roushandeh A, Baba T., Oloomi, M, Fukumoto, M., Induction of apoptosis on K562 cell line and double strand breaks on Colon cancer cell line expressing high affinity receptor for Granulocyte Macrophage ¿colony Stimulating Factor (GM-CSF). . In: Iran Biomed J, 2008, 1-6
2008M Oloomi, S Bouzari: Molecular profile and genetic diversity of cytolethal distending toxin (CDT)-producing Escherichia coli isolates from diarrheal patients. . In: APMIS., 2008, 125-32
2007Habibi Roudkenar M, Bouzari, S. Oloomi, M, Kuwahara,Y., Mohammadi Roushandeh A, Baba T., Fukumoto, M., Assessment of GM-CSF receptors by real-time RT-PCR on cell lines expressing high and low affinity receptors and their relation to cytotoxic effect of chimeric protein (StxA1-GM-CSF). . In: Daru, 2007, 151- -155
2007 Bouzari, S. Jafari, A., Zarepoor, M.,: Distribution of genes encoding different toxins and determination of resistance patterns among diarrhogenic Escherichia coli isolates in Iran. . In: East. Med. Health J. , 2007, 287-293
2006. Oloomi M, Bouzari S, Arshadi M: N-terminus leader sequence of shiga toxin (stx1) is essential for production of active recombinant protein in E. coli. . In: Protein Pept Lett, 2006, 5015
2006Mehryar Habibi Roudkenar, Saeid Bouzari*, Yoshikazu Kuwahara, Amaneh Mohammadi Roushandeh, Mana Oloomi, Manabu Fukumoto. Recombinant Hybrid Protein, Shiga-Toxin and granulocyte macrophage colony stimulating factor, Effectively Induces Apoptosis of Colon Cancer Cells.. In: World J Gasteroenterol , 2006, 2341--2344
2006M Oloomi and Bouzari, S. Comparison of PCR systems for Detection of different cdt genes in Escherichia coli isolates. . In: Lett Appl Microbiol , 2006, 445-451
2006Oloomi M, Bouzari S, Arshadi M. (2006). N-terminus leader sequence of shiga toxin (stx1) is essential for production of active recombinant protein in E. coli. . In: Protein Pept Lett,, 2006, 5015.
2006. Nader Shahrokhi, Saeid Bouzari and Anis Jafari Priming Hepatitis B Surface (HBsAg) and Core Antigen (HBcAg) Specific Immune Responses by chimeric HBcAg 'a' Determinant. . In: Iran Biomed J, 2006, 61 -68
2006Mehryar Habibi Roudkenar, Saeid Bouzari*, Yoshikazu Kuwahara, Amaneh Mohammadi Roushandeh, Mana Oloomi, Manabu Fukumoto. Recombinant Hybrid Protein, Shiga-Toxin and granulocyte macrophage colony stimulating factor, Effectively Induces Apoptosis of Colon Cancer Cells. . In: World J Gasteroenterol, 2006, 2341-2344
2006Mehryar Habibi Roudkenar, Anis Jafari, Mana Oloomi, and Saeid Bouzari: Selective cytotoxicity of recombinant STXA1-GM-CSF protein in hematopoetic cancer cells. . In: Cell Biol Toxicol , 2006, 213-219
2005.Bouzari, S Oloomi,.M. E.Oswald Detection of cytolethal distending toxin locus cdtB among diarrheagenic Escherichia coli human isolates from Iran.. In: Research in Microbiology, 2005, 137 -144
2005Bouzari, S. A.jafari., A.Zarepoor Distribution of virulence related genes among enteroaggregative Escherichia coli isolates: using Multiplex PCR and hybridization. . In: Infection Genetics and Evolution, 2005, 79 -83
2005Habibi Roudkenar,M., Bouzari S., Oloomi M., Jafari A., Shahrokhi N., Shokrgozar MA. Expression of a chimeric protein containing the catalytic domain of Shiga-toxin and human Granulocyte Macrophage Colony ¿ Stimulating Factor (h GM-CSF) in Escherichia coli and its recognition by reciprocal antibodies.. In: Iran Biomed J , 2005, 143-148
2004 Mana Oloomi and Saeid Bouzari Improvement of h GM-CSF expression using a fusion system by directing protein to the periplasmic space.. In: Medical Journal of IRI , 2004, 141-146
2003Aslani, M.M., Bouzari, S. An epidemiological study on Verotoxin producing Escherichia coli (VTEC) infection among population of Northern region of Iran. . In: European Journal of Epidemiology , 2003, 345-349
2002 Shahrokhi, N., Jafari, A., Bakayev, V., Schirnbeck, R., Reinan, J., Bouzari S. .Construction of Hybrid gene of Hepatitis B surface Antigen carrying Heat-stable Enterotoxin of Escherichia coli and it's Expression in mammalian cell line. . In: Iran Biomed J, 2002, 647-53
2001 Le Bouguenec C,Laliouli L,du Merle L,Jouve M,Courcoux P, Bouzari S, Selvarangan R, Nowicki BJ, Germani Y, Adremont A,Gounon P, Garcia MI Characterization of AfaE adhesins produced by extraintestinal and intestinal human Escherichia coli isolates: PCR assays for detection of Afa adhesins that do or do not recognize Dr blood group antigens. . In: J Clin Microbiol, 2001, 1738-45
2001Bouzari, S., Jafari, A., Azizi, A., Oloomi, M., Nataro, J.P. Characterization of enteroaggregative Escherichia coli (EAEC) isolates from Iranian children. Am J Trop Med Hug. . In: Am J Trop Med Hyg, 2001, 13-14
2001Jafari, A., Katouli M., Shokouhi, F,and Bouzari S. Detection and characterization of Verotoxin-producing strains among non-sorbitol fermenting Escherichia coli. . In: East. Med. Health J., 2001, 121-127