| 2021 | Salama, Yousef and Jaradat, Nidal and Hattori, Koichi and Heissig, Beate: Aloysia Citrodora Essential Oil Inhibits Melanoma Cell Growth and Migration by Targeting HB-EGF-EGFR Signaling. In: International journal of molecular sciences, 22, 2021, 8151 |
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| 2021 | Heissig, Beate and Salama, Yousef and Takahashi, Satoshi and Okumura, Ko and Hattori, Koichi: The Multifaceted Roles of EGFL7 in Cancer and Drug Resistance. In: Cancers, 13, 2021, 1014 |
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| 2021 | Heissig, Beate and Salama, Yousef and Osada, Taro and Okumura, Ko and Hattori, Koichi: The multifaceted role of plasminogen in cancer. In: International Journal of Molecular Sciences, 22, 2021, 2304 |
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| 2020 | Sato-Okabayashi, Yayoi and Isoda, Kikuo and Heissig, Beate and Kadoguchi, Tomoyasu and Akita, Koji and Kitamura, Kenichi and Shimada, Kazunori and Hattori, Koichi and Daida, Hiroyuki: Low-dose oral cyclophosphamide therapy reduces atherosclerosis progression by decreasing inflammatory cells in a murine model of atherosclerosis. In: IJC Heart \& Vasculature, 28, 2020, 100529 |
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| 2020 | Hattori, Koichi and Takahashi, Satoshi and Osada, Taro and Heissig, Beate: Roles of the fibrinolytic system in inflammatory diseases. In: Japanese Journal of Thrombosis and Hemostasis, 2020, 388--393 |
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| 2020 | Salama, Yousef and Heida, Andries Hendrik and Yokoyama, Kazuaki and Takahashi, Satoshi and Hattori, Koichi and Heissig, Beate: The EGFL7-ITGB3-KLF2 axis enhances survival of multiple myeloma in preclinical models. In: Blood advances, 4, 2020, 1021--1037 |
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| 2020 | Hattori, Koichi and Shimazu, Hiroshi and Takahashi, Satoshi and Heissig, Beate: The Role of Fibrinolytic Factors, a Subset of Angiocrine Factors in Cytokine Storm-Associated Diseases. In: Blood, 136, 2020, 33--34 |
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| 2020 | Heissig, Beate and Salama, Yousef and Takahashi, Satoshi and Osada, Taro and Hattori, Koichi: The multifaceted role of plasminogen in inflammation. In: Cellular signalling, 2020, 109761 |
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| 2019 | Salama, Yousef and Lin, Shiou-Yuh and Dhahri, Douaa and Hattori, Koichi and Heissig, Beate: The fibrinolytic factor tPA drives LRP1-mediated melanoma growth and metastasis. In: The FASEB Journal, 33, 2019, 3465--3480 |
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| 2018 | Munakata, Shinya and Honjo, Kumpei and Tashiro, Yoshihiro and Sakamoto, Kazuhiro and Yousef, Salama M and Hattori, Kouchi and Heissig, Beate: 811-Plasminogen Activator Inhibitor-1 is a Therapeutic Target for the Prevention of Postoperative Adhesion in Mice. In: Gastroenterology, 154, 2018, S--166 |
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| 2017 | Shimazu, Hiroshi and Munakata, Shinya and Tashiro, Yoshihiko and Salama, Yousef and Dhahri, Douaa and Eiamboonsert, Salita and Ota, Yasunori and Onoda, Haruo and Tsuda, Yuko and Okada, Yoshio and others: Pharmacological targeting of plasmin prevents lethality in a murine model of macrophage activation syndrome. In: Blood, The Journal of the American Society of Hematology, 130, 2017, 59--72 |
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| 2017 | Honjo, Kumpei and Munakata, Shinya and Tashiro, Yoshihiko and Salama, Yousef and Shimazu, Hiroshi and Eiamboonsert, Salita and Dhahri, Douaa and Ichimura, Atsuhiko and Dan, Takashi and Miyata, Toshio and others: Plasminogen activator inhibitor-1 regulates macrophage-dependent postoperative adhesion by enhancing EGF-HER1 signaling in mice. In: The FASEB Journal, 31, 2017, 2625--2637 |
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| 2017 | Salama, Yousef and Hattori, Koichi and Heissig, Beate: The angiogenic factor Egfl7 alters thymogenesis by activating Flt3 signaling. In: Biochemical and biophysical research communications, 490, 2017, 209--216 |
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| 2017 | Salama, Yousef and Hattori, Koichi and Heissig, Beate: The angiogenic factor Egfl7 enhances thymogenesis by activating Flt3 signaling. 2017, |
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| 2017 | Eiamboonsert, Salita and Salama, Yousef and Watarai, Hiroshi and Dhahri, Douaa and Tsuda, Yuko and Okada, Yoshio and Hattori, Koichi and Heissig, Beate: The role of plasmin in the pathogenesis of murine multiple myeloma. In: Biochemical and biophysical research communications, 488, 2017, 387--392 |
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| 2016 | Heissig, Beate and Eiamboonsert, Salita and Salama, Yousef and Shimazu, Hiroshi and Dhahri, Douaa and Munakata, Shinya and Tashiro, Yoshihiko and Hattori, Koichi: Cancer therapy targeting the fibrinolytic system. In: Advanced drug delivery reviews, 99, 2016, 172--179 |
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| 2016 | Dhahri, Douaa and Sato-Kusubata, Kaori and Ohki-Koizumi, Makiko and Nishida, Chiemi and Tashiro, Yoshihiko and Munakata, Shinya and Shimazu, Hiroshi and Salama, Yousef and Eiamboonsert, Salita and Nakauchi, Hiromitsu and others: Fibrinolytic crosstalk with endothelial cells expands murine mesenchymal stromal cells. In: Blood, The Journal of the American Society of Hematology, 128, 2016, 1063--1075 |
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| 2015 | Munakata, Shinya and Tashiro, Yoshihiko and Nishida, Chiemi and Sato, Aki and Komiyama, Hiromitsu and Shimazu, Hiroshi and Dhahri, Douaa and Salama, Yousef and Eiamboonsert, Salita and Takeda, Kazuyoshi and others: Inhibition of Plasmin Protects Against Colitis in Mice by Suppressing Matrix Metalloproteinase 9--Mediated Cytokine Release From Myeloid Cells. In: Gastroenterology, 148, 2015, 565--578 |
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| 2015 | Sato, A and Nishida, C and Sato-Kusubata, K and Ishihara, M and Tashiro, Y and Gritli, I and Shimazu, H and Munakata, S and Yagita, H and Okumura, K and others: Inhibition of plasmin attenuates murine acute graft-versus-host disease mortality by suppressing the matrix metalloproteinase-9-dependent inflammatory cytokine storm and effector cell trafficking. In: Leukemia, 29, 2015, 145--156 |
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| 2015 | Heissig, Beate and Dhahri, Douaa and Eiamboonsert, Salita and Salama, Yousef and Shimazu, Hiroshi and Munakata, Shinya and Hattori, Koichi: Role of mesenchymal stem cell-derived fibrinolytic factor in tissue regeneration and cancer progression. In: Cellular and molecular life sciences, 72, 2015, 4759--4770 |
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| 2015 | Munakata, Shinya and Tashiro, Yoshihiko and Sakamoto, Kazuhiro and Okada, Yoshio and Heissig, Beate and Hattori, Koichi: Sa1250 Inhibition of Plasmin Protects Against Experimental Colitis by Suppressing the Matrix Metalloproteinase-9-Mediated Cytokine Release From Myeloid Cells. In: Gastroenterology, 148, 2015, S--269 |
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| 2014 | Nakahara, Fumio and Kitaura, Jiro and Uchida, Tomoyuki and Nishida, Chiemi and Togami, Katsuhiro and Inoue, Daichi and Matsukawa, Toshihiro and Kagiyama, Yuki and Enomoto, Yutaka and Kawabata, Kimihito C and others: Hes1 promotes blast crisis in chronic myelogenous leukemia through MMP-9 upregulation in leukemic cells. In: Blood, The Journal of the American Society of Hematology, 123, 2014, 3932--3942 |
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| 2013 | Caiado, Francisco and Carvalho, T{\^a}nia and Rosa, Isadora and Rem{\'e}dio, Leonor and Costa, Ana and Matos, Jo{\~a}o and Heissig, Beate and Yagita, Hideo and Hattori, Koichi and da Silva, Jo{\~a}o Pereira and others: Bone Marrow--Derived CD11b+ Jagged2+ Cells Promote Epithelial-to-Mesenchymal Transition and Metastasization in Colorectal Cancer. In: Cancer research, 73, 2013, 4233--4246 |
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| 2012 | Tashiro, Yoshihiko and Nishida, Chiemi and Sato-Kusubata, Kaori and Ohki-Koizumi, Makiko and Ishihara, Makoto and Sato, Aki and Gritli, Ismael and Komiyama, Hiromitsu and Sato, Yayoi and Dan, Takashi and others: Inhibition of PAI-1 induces neutrophil-driven neoangiogenesis and promotes tissue regeneration via production of angiocrine factors in mice. In: Blood, The Journal of the American Society of Hematology, 119, 2012, 6382--6393 |
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| 2012 | Nishida, Chiemi and Sato-Kusubata, Kaori and Tashiro, Yoshihiko and Gritli, Ismael and Sato, Aki and Ohki-Koizumi, Makiko and Morita, Yohei and Nagano, Makoto and Sakamoto, Takeharu and Koshikawa, Naohiko and others: MT1-MMP Plays a Critical Role in Hematopoiesis by Regulating HIF-Mediated Chemo-/Cytokine Gene Transcription within Niche Cells.. In: Blood, 120, 2012, 2351 |
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| 2012 | Nishida, Chiemi and Kusubata, Kaori and Tashiro, Yoshihiko and Gritli, Ismael and Sato, Aki and Ohki-Koizumi, Makiko and Morita, Yohei and Nagano, Makoto and Sakamoto, Takeharu and Koshikawa, Naohiko and others: MT1-MMP plays a critical role in hematopoiesis by regulating HIF-mediated chemokine/cytokine gene transcription within niche cells. In: Blood, The Journal of the American Society of Hematology, 119, 2012, 5405--5416 |
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| 2012 | Heissig, Beate and Ohki-Koizumi, Makiko and Tashiro, Yoshihiko and Gritli, Ismael and Sato-Kusubata, Kaori and Hattori, Koichi: New functions of the fibrinolytic system in bone marrow cell-derived angiogenesis. In: International journal of hematology, 95, 2012, 131--137 |
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| 2012 | Ishihara, M and Nishida, C and Tashiro, Y and Gritli, I and Rosenkvist, J and Koizumi, M and Okaji, Y and Yamamoto, R and Yagita, H and Okumura, K and others: Plasmin inhibitor reduces T-cell lymphoid tumor growth by suppressing matrix metalloproteinase-9-dependent CD11b+/F4/80+ myeloid cell recruitment. In: Leukemia, 26, 2012, 332--339 |
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| 2012 | Okaji, Yurai and Tashiro, Yoshihiko and Gritli, Ismael and Nishida, Chiemi and Sato, Aki and Ueno, Yoko and Gonzalez, Sandra Del Canto and Ohki-Koizumi, Makiko and Akiyama, Haruyo and Nakauchi, Hiromitsu and others: Plasminogen deficiency attenuates postnatal erythropoiesis in male C57BL/6 mice through decreased activity of the LH-testosterone axis. In: Experimental hematology, 40, 2012, 143--154 |
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| 2011 | Piao, Jiang-Hu and Hasegawa, Mizuho and Heissig, Beate and Hattori, Koichi and Takeda, Kazuyoshi and Iwakura, Yoichiro and Okumura, Ko and Inohara, Naohiro and Nakano, Hiroyasu: Tumor Necrosis Factor Receptor-associated Factor (TRAF) 2 Controls Homeostasis of the Colon to Prevent Spontaneous Development of Murine Inflammatory Bowel Disease*♦. In: Journal of Biological Chemistry, 286, 2011, 17879--17888 |
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| 2010 | Aoki, Naohito and Yokoyama, Rumi and Asai, Noriyuki and Ohki, Makiko and Ohki, Yuichi and Kusubata, Kaori and Heissig, Beate and Hattori, Koichi and Nakagawa, Yoshimi and Matsuda, Tsukasa: Adipocyte-derived microvesicles are associated with multiple angiogenic factors and induce angiogenesis in vivo and in vitro. In: Endocrinology, 151, 2010, 2567--2576 |
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| 2010 | Nishida, Chiemi and Heissig, Beate and Tashiro, Yoshihiko and Seiki, Motoharu and Nakauchi, Hiromitsu and Hattori, Koichi: MT1-MMP Plays a Critical Role In the Modulation of Hematopoiesis.. In: Blood, 116, 2010, 3851 |
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| 2010 | Heissig, Beate and Nishida, Chiemi and Tashiro, Yoshihiko and Sato, Yayoi and Ishihara, Makoto and Ohki, Makiko and Gritli, Ismael and Rosenkvist, Jeanette and Hattori, Koichi: Role of neutrophil-derived matrix metalloproteinase-9 in tissue regeneration. In: Histology and histopathology, Vol. 25, n{\textordmasculine} 6 (2010), 2010, |
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| 2010 | Ohki, Makiko and Ohki, Yuichi and Ishihara, Makoto and Nishida, Chiemi and Tashiro, Yoshihiko and Akiyama, Haruyo and Komiyama, Hiromitsu and Lund, Leif R and Nitta, Atsumi and Yamada, Kiyofumi and others: Tissue type plasminogen activator regulates myeloid-cell dependent neoangiogenesis during tissue regeneration. In: Blood, The Journal of the American Society of Hematology, 115, 2010, 4302--4312 |
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| 2009 | Heissig, Beate and Ohki, Makiko and Ishihara, Makoto and Tashiro, Yoshihiko and Nishida, Chiemi and Gritli, Ismael and Rosenkvist, Jeanette and Hattori, Koichi: Contribution of the fibrinolytic pathway to hematopoietic regeneration. In: Journal of cellular physiology, 221, 2009, 521--525 |
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| 2008 | Hattori, Koichi and Ishihara, Makoto and Heissig, Beate: Bone marrow-derived cells contribute to niche formation in cancer progression. In: Clinical calcium, 18, 2008, 480--487 |
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| 2008 | Kerbel, Robert S and Benezra, Robert and Lyden, David C and Hattori, Koichi and Heissig, Beate and Nolan, Daniel J and Mittal, Vivek and Shaked, Yuval and Dias, Sergio and Bertolini, Francesco and others: Endothelial progenitor cells are cellular hubs essential for neoangiogenesis of certain aggressive adenocarcinomas and metastatic transition but not adenomas. In: Proceedings of the National Academy of Sciences, 105, 2008, E54--E54 |
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| 2008 | Nishikii, Hidekazu and Eto, Koji and Tamura, Noriko and Hattori, Koichi and Heissig, Beate and Kanaji, Taisuke and Sawaguchi, Akira and Goto, Shinya and Ware, Jerry and Nakauchi, Hiromitsu: Metalloproteinase regulation improves in vitro generation of efficacious platelets from mouse embryonic stem cells. In: The Journal of experimental medicine, 205, 2008, 1917--1927 |
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| 2007 | Kiaei, Mahmoud and Kipiani, Khatuna and Calingasan, Noel Y and Wille, Elizabeth and Chen, Junyu and Heissig, Beate and Rafii, Shahin and Lorenzl, Stefan and Beal, M Flint: Matrix metalloproteinase-9 regulates TNF-$\alpha$ and FasL expression in neuronal, glial cells and its absence extends life in a transgenic mouse model of amyotrophic lateral sclerosis. In: Experimental neurology, 205, 2007, 74--81 |
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| 2007 | HEISSIG, B: Novel functions for a fibrinolytic pathway in controlling hematopoiesis. In: Cell Stem Cell., 1, 2007, 658--670 |
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| 2007 | Heissig, Beate and Lund, Leif R and Akiyama, Haruyo and Ohki, Makiko and Morita, Yohei and R{\o}mer, John and Nakauchi, Hiromitsu and Okumura, Ko and Ogawa, Hideoki and Werb, Zena and others: The plasminogen fibrinolytic pathway is required for hematopoietic regeneration. In: Cell Stem Cell, 1, 2007, 658--670 |
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| 2006 | Jin, David K and Shido, Koji and Kopp, Hans-Georg and Petit, Isabelle and Shmelkov, Sergey V and Young, Lauren M and Hooper, Andrea T and Amano, Hideki and Avecilla, Scott T and Heissig, Beate and others: Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytes. In: Nature medicine, 12, 2006, 557--567 |
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| 2006 | Fietz, Thomas and Hattori, Koichi and Thiel, Eckhard and Heissig, Beate: Increased soluble urokinase plasminogen activator receptor (suPAR) serum levels after granulocyte colony-stimulating factor treatment do not predict successful progenitor cell mobilization in vivo. In: Blood, 107, 2006, 3408--3409 |
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| 2006 | Avecilla, ST and Heissig, B and Hattori, K and Zhang, F and Hicklin, DJ and Wu, Y and Zhu, Z and Dunn, A and Salari, H and Werb, Z and others: PMCID: PMC1794071.. In: Biophys Res Commun, 348, 2006, 192--9 |
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| 2005 | Heissig, Beate and Ohki, Yuichi and Sato, Yayoi and Rafii, Shahin and Werb, Zena and Hattori, Koichi: A role for niches in hematopoietic cell development. In: Hematology, 10, 2005, 247--253 |
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| 2005 | Sato, Yayoi and Ohki, Yuichi and Akiyama, Haruyo and Daida, Hiroyuki and Heissig, Beate and Hattori, Koichi: Administration of Low-Dose Cyclophosphamide Reduces Progression of Atherosclerosis in Mice by Controlling the Cellular Microenvironment.. In: Blood, 106, 2005, 4452 |
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| 2005 | Ohki, Yuichi and Heissig, Beate and Sato, Yayoi and Akiyama, Haruyo and Zhu, Zhenping and Hicklin, Daniel J and Shimada, Kazunori and Ogawa, Hideoki and Daida, Hiroyuki and Hattori, Koichi and others: Granulocyte colony-stimulating factor promotes neovascularization by releasing vascular endothelial growth factor from neutrophils. In: The FASEB journal, 19, 2005, 2005--2007 |
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| 2005 | Heissig, Beate and Rafii, Shahin and Akiyama, Haruyo and Ohki, Yuichi and Sato, Yayoi and Rafael, Tejada and Zhu, Zhenping and Hicklin, Daniel J and Okumura, Ko and Ogawa, Hideoki and others: Low-dose irradiation promotes tissue revascularization through VEGF release from mast cells and MMP-9--mediated progenitor cell mobilization. In: Journal of Experimental Medicine, 202, 2005, 739--750 |
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| 2005 | Fietz, Thomas and Hattori, Koichi and Thiel, Eckhard and Heissig, Beate: on May 13, 2016. by guest. In: Blood, 105, 2005, 2198--2205 |
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| 2004 | Avecilla, Scott T and Hattori, Koichi and Heissig, Beate and Tejada, Rafael and Liao, Fang and Shido, Koji and Jin, David K and Dias, Sergio and Zhang, Fan and Hartman, Travis E and others: Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis. In: Nature medicine, 10, 2004, 64--71 |
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| 2004 | Ohki, Yuichi and Hattori, Kouichi and Beate, Heissig and Satoh, Yayoi and Furuhata, Atsushi and Nakamura, Shinji and Shimada, Kazunori and Ohsaka, Akimichi and Daida, Hiroyuki: OE-208 Glanulocyte Colony-Stimulating Factor (G-CSF) Contributes to Mobilization of Bone Marrow-Derived Endothelial Progenitor Cells (EPCs) for Ischemic Neovascularization (Angiogenesis 1 (M): OE26)(Oral Presentation (English)). In: Circulation journal: official journal of the Japanese Circulation Society, 68, 2004, 191 |
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| 2003 | Heissig, Beate and Hattori, Koichi and Friedrich, Matthias and Rafii, Shahin and Werb, Zena: Angiogenesis: vascular remodeling of the extracellular matrix involves metalloproteinases. In: Current opinion in hematology, 10, 2003, 136--141 |
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| 2003 | Rafii, Shahin and Avecilla, Scott and Shmelkov, Sergey and Shido, Koji and Tejada, Rafael and Moore, Malcolm AS and Heissig, Beate and Hattori, Koichi: Angiogenic factors reconstitute hematopoiesis by recruiting stem cells from bone marrow microenvironment. In: Annals of the New York Academy of Sciences, 996, 2003, 49--60 |
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| 2003 | Ohki, Y and Heissig, B and Satoh, Y and Shibata, M and Shimada, K and Ohsaka, A and Daida, H and Hattori, K: Glanulocyte colony-stimulating factor (G-CSF) contributes to mobilization of bone marrow-derived endothelial progenitor cells for ischemic neovascularization.. BLOOD. 2003. 39A--39A |
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| 2003 | Heissig, B and Tejada, R and Werb, Z and Rafii, S and Hattori, K: Marrow regeneration requires a functional vascular niche.. BLOOD. 2003. 531A--531A |
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| 2003 | Rabbany, Sina Y and Heissig, Beate and Hattori, Koichi and Rafii, Shahin: Molecular pathways regulating mobilization of marrow-derived stem cells for tissue revascularization. In: Trends in molecular medicine, 9, 2003, 109--117 |
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| 2003 | Heissig, Beate and Werb, Zena and Rafii, Shahin and Hattori, Koichi: Role of c-kit/Kit ligand signaling in regulating vasculogenesis. In: Thrombosis and haemostasis, 90, 2003, 570--576 |
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| 2003 | Hattori, Koichi and Heissig, Beate and Rafii, Shahin: The regulation of hematopoietic stem cell and progenitor mobilization by chemokine SDF-1. In: Leukemia \& lymphoma, 44, 2003, 575--582 |
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| 2002 | Hattori, K and Heissig, B and Goshima, M and Eaton, D and Ferris, B and Tejeda, R and Nagaoka, I and Crystal, RG and Lyden, D and de Sauvage, FJ and others: Chemokine-mediated enhanced megakaryocyte motility is essential and sufficient for thrombopoietin-independent thrombopoiesis.. BLOOD. 2002. 125A--125A |
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| 2002 | Rafii, S and Heissig, B and Hattori, K: Efficient mobilization and recruitment of marrow-derived endothelial and hematopoietic stem cells by adenoviral vectors expressing angiogenic factors. In: Gene therapy, 9, 2002, 631--641 |
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| 2002 | Salven, Petri and Hattori, Koichi and Heissig, Beate and Rafii, Shahin: Interleukin-1$\alpha$ (IL-1$\alpha$) promotes angiogenesis in vivo via VEGFR-2 pathway by inducing inflammatory cell VEGF synthesis and secretion. In: The FASEB Journal, 16, 2002, 1471--1473 |
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| 2002 | Heissig, B and Tejeda, R and Friedrich, M and Werb, Z and Rafii, S and Hattori, K: MMP-9-mediated activation and release of pro-angiogenic factors following irradiation.. Blood. 2002. 124A--124A |
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| 2002 | Hattori, Koichi and Heissig, Beate and Wu, Yan and Dias, Sergio and Tejada, Rafael and Ferris, Barbara and Hicklin, Daniel J and Zhu, Zhenping and Bohlen, Peter and Witte, Larry and others: Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1+ stem cells from bone-marrow microenvironment. In: Nature medicine, 8, 2002, 841--849 |
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| 2002 | Rafii, Shahin and Lyden, David and Benezra, Robert and Hattori, Koichi and Heissig, Beate: Vascular and haematopoietic stem cells: novel targets for anti-angiogenesis therapy?. In: Nature Reviews Cancer, 2, 2002, 826--835 |
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| 2001 | Hattori, K and Heissig, B and Dias, S and Hicklin, DJ and Wu, Y and Witte, L and Zhu, Z and Lyden, D and Hendrikx, PJ and Visser, JWM and others: Activation of VEGF receptor-1 (VEGFR1, Flt-1) expressed on hematopoietic stem cells promotes cell motility and is essential for marrow reconstitution.. Blood. 2001. 710A--711A |
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| 2001 | Lyden, David and Hattori, Koichi and Dias, Sergio and Costa, Carla and Blaikie, Pamela and Butros, Linda and Chadburn, Amy and Heissig, Beate and Marks, Willy and Witte, Larry and others: Impaired recruitment of bone-marrow--derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. In: Nature medicine, 7, 2001, 1194--1201 |
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| 2001 | Dias, Sergio and Hattori, Koichi and Heissig, Beate and Zhu, Zhenping and Wu, Yan and Witte, Larry and Hicklin, Daniel J and Tateno, Masatoshi and Bohlen, Peter and Moore, Malcolm AS and others: Inhibition of both paracrine and autocrine VEGF/VEGFR-2 signaling pathways is essential to induce long-term remission of xenotransplanted human leukemias. In: Proceedings of the National Academy of Sciences, 98, 2001, 10857--10862 |
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| 2001 | Heissig, B and Hattori, K and Dias, S and Lyden, D and Crystal, RG and Werb, Z and Moore, MAS and Rafii, S: Matrix metalloproteinase-9 mediated release of stem cell active cytokines is essential for hematopoietic reconstitution and mobilization of stem cells.. BLOOD. 2001. 831A--831A |
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| 2001 | Moore, MAS and Hattori, K and Heissig, B and SHIEH, J-H and Dias, S and Crystal, RG and Rafii, S: Mobilization of endothelial and hematopoietic stem and progenitor cells by adenovector-mediated elevation of serum levels of SDF-1, VEGF, and angiopoietin-1. In: Annals of the New York Academy of Sciences, 938, 2001, 36--47 |
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| 2001 | Moore, MAS and Hattori, K and Heissig, B and Shieh, JH and Dias, S and Crystal, RG and Rafii, S: Part II Stem Cell Mobilization and Engraftment-Mobilization of Endothelial and Hematopoietic Stem and Progenitor Cells by Adenovector-mediated Elevation of Serum Levels of SDF-1, VEGF, and. In: Annals of the New York Academy of Sciences-Paper Edition, 938, 2001, 36--47 |
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| 2001 | Hattori, Koichi and Heissig, Beate and Tashiro, Kei and Honjo, Tasuku and Tateno, Masatoshi and Shieh, Jae-Hung and Hackett, Neil R and Quitoriano, Mannix S and Crystal, Ronald G and Rafii, Shahin and others: Plasma elevation of stromal cell--derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells. In: Blood, The Journal of the American Society of Hematology, 97, 2001, 3354--3360 |
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| 2001 | Rafii, DC and Shmelkov, S and Dias, S and Hattori, K and Heissig, B and Usenko, J and Chadburn, A and Benezra, R and Lyden, D: VEGF-induced upregulation of Id1 and Id3 proteins are required for mobilization of marrow-derived precursor cells to the tumor vasculature.. Blood. 2001. 822A--822A |
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| 2001 | Hattori, Koichi and Dias, Sergio and Heissig, Beate and Hackett, Neil R and Lyden, David and Tateno, Masatoshi and Hicklin, Daniel J and Zhu, Zhenping and Witte, Larry and Crystal, Ronald G and others: Vascular endothelial growth factor and angiopoietin-1 stimulate postnatal hematopoiesis by recruitment of vasculogenic and hematopoietic stem cells. In: The Journal of experimental medicine, 193, 2001, 1005--1014 |
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| 2000 | Dias, Sergio and Hattori, Koichi and Zhu, Zhenping and Heissig, Beate and Choy, Margaret and Lane, William and Wu, Yan and Chadburn, Amy and Hyjek, Elizabeth and Gill, Muhammad and others: Autocrine stimulation of VEGFR-2 activates human leukemic cell growth and migration. In: The Journal of clinical investigation, 106, 2000, 511--521 |
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| 2000 | Heissig, Beate and Pasternak, Günther and Hörner, Susanne and Schwerdtfeger, Rainer and Rossol, Siegfried and Hehlmann, Rüdiger: CD14+ peripheral blood mononuclear cells from chronic myeloid leukemia and normal donors are inhibitory to short-and long-term cultured colony-forming cells. In: Leukemia research, 24, 2000, 217--231 |
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| 2000 | Heissig, B and Hattori, K and Dias, S and Crystal, RG and Wood, J and Moore, MAS and Rafii, S: In vivo inhibition of matrix metalloproteinases blocks chemo-cytokine induced endothelial and hematopoietic stem cell mobilization.. Blood. 2000. 540A--540A |
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| 2000 | Hattori, K and Dias, S and Heissig, B and Crystal, RG and Zhu, Z and Witte, L and Hicklin, D and Moore, MAS and Rafii, S: Inhibition of VEGFR-2 signaling pathway ameliorates VEGF-induced fatal complications in mice.. BLOOD. 2000. 502A--502A |
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| 2000 | Dias, S and Hattori, K and Heissig, B and Zhu, Z and Hicklin, D and Witte, L and Moore, MAS and Rafii, S: Inhibition of both autocrine and paracrine VEGF/VEGFR-2 angiogenic pathways is essential to induce long term remission of human leukemias xenotransplanted into NOD-SCID mice.. Blood. 2000. 117A--117A |
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| 2000 | Schultheis, B and Heissig, B and Pasternak, G and Hörner, S and Hehlmann, R: Interferon-alpha-treated patients with chronic myelogenous leukemia show BCR/ABL-positive peripheral blood progenitor cells surviving long-term culture.. In: Folia biologica, 46, 2000, 251--255 |
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| 2000 | Lane, William J and Dias, Sergio and Hattori, Koichi and Heissig, Beate and Choy, Margaret and Rabbany, Sina Y and Wood, Jeanette and Moore, Malcolm AS and Rafii, Shahin: Stromal-derived factor 1--induced megakaryocyte migration and platelet production is dependent on matrix metalloproteinases. In: Blood, The Journal of the American Society of Hematology, 96, 2000, 4152--4159 |
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| 2000 | Hattori, K and Dias, S and Heissig, B and Crystal, RG and Moore, MAS and Rafii, S: VEGF and angiopoietin-1 stimulate post-natal hematopoiesis by mobilization and recruitment of vasculogenic and hematopoietic stem cells.. BLOOD. 2000. 820A--821A |
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| 1999 | Franco, S and Vyas, Y and McKenzie, KL and Boklan, J and Orme, L and Heissig, B and Feugier, P and Shieh, JH and Dupont, B and Moore, MAS: Differential upregulation of telomerase in NK (natural killer) and T lymphocytes in vitro.. BLOOD. 1999. 4A--4A |
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| 1999 | Pasternak, G and Schultheis, B and Heissig, B and Hörner, S and Sick, C and Hehlmann, R: Does long-term culture favor normal clonogenic cells from interferon-treated patients with chronic myelogenous leukemia?. In: Leukemia, 13, 1999, S55--S64 |
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| 1999 | Lane, WJ and Dias, S and Hattori, K and Heissig, B and Choy, M and Lam, G and Moore, MAS and Rafii, S: Matrix metalloproteinase-9 (MMP-9) is essential for chemokine-induced megakaryocyte migration and platelet formation: Induction of thrombocytopenia by a synthetic MMP inhibitor.. BLOOD. 1999. 689A--689A |
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| 1999 | Heissig, B and Hattori, K and Dias, S and Tashiro, K and Honjo, T and Rafii, S and Crystal, RG and Moore, MAS: Stormal-derived factor-1 (SDF1) induces TNF-alpha mediated progenitor cell apoptosis of CD34+ cells derived from chronic myeloid leukemia (CML).. BLOOD. 1999. 100A--100A |
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| 1998 | Horner, S and Heissig, B and Schwerdtfeger, R and Pasternak, G and Hehlmann, R: AC133-positive cells in the peripheral blood and bone marrow of patients with chronic myelogenous leukemia. Blood. 1998. 316B--316B |
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| 1998 | Heissig, B and Schultheis, B and Horner, S and Pasternak, G and Hehlmann, R: Stroma non-contact conditions improve the survival of benign long-term cultured cells in peripheral blood (PB) of CML patients.. BLOOD. 1998. 245B--245B |
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| 1997 | Sick, C and Schultheis, B and Pasternak, G and Heissig, B and Hehlmann, R: Follow-up of nonclonal hematopoetic progenitor cells in the peripheral blood of interferon-alpha treated patients with chronic myelogenous leukemia (CML).. BLOOD. 1997. 4016--4016 |
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| 1997 | Heissig, B and Pasternak, G and Schwerdtfeger, R and Hehlmann, R: Inhibition of short-and long-term cultured colony-forming cells caused by CD14+ peripheral blood cells is not a CML specific phenomenon.. BLOOD. 1997. 3995--3995 |
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| 1997 | Schultheis, B and Heissig, B and Sick, C and Hochhaus, A and Pasternak, G and Hehlmann, R: Long-term cultured colony-forming cells from peripheral blood of CML patients under interferon-alpha or hydroxyurea therapy show differences in BCR-ABL-positivity.. BLOOD. 1997. 4015--4015 |
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| n.n. | Heissig, Beate: Role of tissue plasminogen activator for hematopoietic-cell driven neoangiogenesis. In: 財団年報 第 22 号, n.n., |
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