Prof. Dr. Johannes Klein

Profil

Derzeitige StellungProfessor W-2 und Äquivalente
FachgebietEndokrinologie, Diabetologie, Metabolismus
KeywordsAdipose tissue, Diabetes, Inkretin Biology, Insulin Resistance Syndrome, Obesity

Aktuelle Kontaktadresse

LandDeutschland
OrtLübeck
Websitewww.adipo-site.org

Gastgeber*innen während der Förderung

Prof. Dr. Daniel C. DruckerToronto General Hospital, University of Toronto, Toronto
Dr. Chung-Wai ChowDepartment of Medicine, University of Toronto, Toronto
Beginn der ersten Förderung16.07.2004

Programm(e)

2004Feodor Lynen-Forschungsstipendien-Programm

Publikationen (Auswahl)

2008Sören Westphal, Nina Perwitz, K. Alexander H. Iwen, Daniel Kraus, Raffael Schick, Mathias Fasshauer, Johannes Klein: Expression of ATRAP in adipocytes and negative regulation by beta-adrenergic stimulation of JAK/STAT. In: Horm Metab Res, 2008, 165-171
2008Alexander Iwen, Özge Senyaman, Arne Schwartz, Maren Drenckhan, Britta Meier, Dirk Hadaschik, Johannes Klein: Melanocortin crosstalk with adipose functions: ACTH directly induces insulin resistance, promotes a pro-inflammatory adipokine profile, and stimulates UCP-1 in adipocytes. . In: Journal of Endocrinology, 2008, 465-472
2007Wanda Mäuser, Nina Perwitz, Britta Meier, Mathias Fasshauer, Johannes Klein: Direct adipotropic actions of atorvastatin: differentiation state-dependent induction of apoptosis, modulation of endocrine function, and inhibition of glucose uptake.. In: European Journal of Pharmacology, 2007, 37-46
2007Johannes Klein, Mathias Fasshauer: What are subcutaneous adipocytes really good for? . In: Exp Dermatol, 2007, 50-53
2006Johannes Klein, Nina Perwitz, Daniel Kraus, Mathias Fasshauer: Adipose tissue as source and target for novel therapies. In: Trends in Endocrinology and Metabolism, 2006, 26-32
2006Nina Perwitz, Mathias Fasshauer, Johannes Klein: Cannabinoid receptor signaling directly inhibits thermogenesis and alters expression of adiponectin and visfatin. . In: Horm Metab Res, 2006, 356-358
2006Alexander Iwen, Nina Perwitz, Daniel Kraus, Mathias Fasshauer, Johannes Klein: Putting fat cells onto the road map to novel therapeutic strategies.. In: Discovery Medicine, 2006, 75-81
2005Daniel Kraus, Jessica Jäger, Britta Meier, Mathias Fasshauer, Johannes Klein: Aldosterone Inhibits Uncoupling Protein-1, Induces Insulin Resistance, and Stimulates Proinflammatory Adipokines in Adipocytes. In: Horm Metab Res, 2005, 455-459
2005Nina Perwitz, Henning Sievert, Britta Meier, Maren Drenckhan, Mathias Fasshauer, Johannes Klein: Cocaine- and Amphetamine-Related Transcript (CART) directly stimulates UCP-1 expression and enhances insulin-induced glucose uptake. In: Adipocytes, 2005, 145-150
2005Daniel Kraus, Mathias Fasshauer, and Johannes Klein: NEUROPEPTIDE AND PERIPHERAL HORMONE CROSSTALK WITH ADIPOCYTE FUNCTION. In: Adipocytes, 2005, 95-120
2005Johannes Klein, Horst Lorenz Fehm: Unusual presentation of hypophysitis preceding an empty sella in a 75-year-old woman.. In: Neuro Endocrinol Lett, 2005, 757-758
2004Johannes Klein, Sören Westphal, Daniel Kraus, Britta Meier, Nina Perwitz, Volker Ott, Mathias Fasshauer and H Harald Klein: Metformin inhibits leptin secretion via a mitogen-activated protein kinase signalling pathway in brown adipocytes. In: J Endocrinol., 2004, 299-307