Dr. Katharina Wandera

Profil

Derzeitige StellungDoktorand
FachgebietMedizinische Mikrobiologie und Mykologie, Hygiene, Molekulare Infektionsbiologie,Stoffwechselphysiologie, Biochemie und Genetik der Mikroorganismen
KeywordsJumbophages, bacterial defence systems, Phage-encoded anti-defence mechanisms, Phage-host interactions

Aktuelle Kontaktadresse

LandNeuseeland
OrtDunedin
Universität/InstitutionUniversity of Otago
Institut/AbteilungDepartment of Microbiology and Immunology

Gastgeber*innen während der Förderung

Prof. Dr. Peter FineranDepartment of Microbiology and Immunology, University of Otago, Dunedin
Beginn der ersten Förderung01.10.2024

Programm(e)

2023Feodor Lynen-Forschungsstipendien-Programm für Postdocs

Publikationen (Auswahl)

2025Wandera, Katharina G and Schmelz, Stefan and Migur, Angela and Kibe, Anuja and Lukat, Peer and Achmedov, Tatjana and Caliskan, Neva and Blankenfeldt, Wulf and Beisel, Chase L: AcrVIB1 inhibits CRISPR-Cas13b immunity by promoting unproductive crRNA binding accessible to RNase attack. In: Molecular Cell, 85, 2025, 1162--1175
2025Wandera, Katharina G and Dubrulle, Jeremy and Greene, Russell and Ozturk, Meric and Knott, Gavin and Sashital, Dipali G and Fineran, Peter C: CRISPR2025 New Zealand: Innovation and Collaboration. In: The CRISPR Journal, 8, 2025, 166--173
2025Mahler, Marina and Cui, Liang and Smith, Leah M and Wandera, Katharina G and Dietrich, Oliver and Mayo-Mu{\~n}oz, David and Balamkundu, Seetharamsing and Lee, Megan En and Ye, Hong and Liu, Chuan-Fa and others: Phage arabinosyl-hydroxy-cytosine DNA modifications result in distinct evasion and sensitivity responses to phage defense systems. In: Cell host \& microbe, 33, 2025, 1173--1190
2024Wimmer, Franziska and Englert, Frank and Wandera, Katharina G and Alkhnbashi, Omer S and Collins, Scott P and Backofen, Rolf and Beisel, Chase L: Interrogating two extensively self-targeting Type I CRISPR-Cas systems in Xanthomonas albilineans reveals distinct anti-CRISPR proteins that block DNA degradation. In: Nucleic Acids Research, 52, 2024, 769--783
2024Benz, Fabienne and Camara-Wilpert, Sarah and Russel, Jakob and Wandera, Katharina G and {\v{C}}epait{\.e}, Rimvyd{\.e} and Ares-Arroyo, Manuel and Gomes-Filho, Jos{\'e} Vicente and Englert, Frank and Kuehn, Johannes A and Gloor, Silvana and others: Type IV-A3 CRISPR-Cas systems drive inter-plasmid conflicts by acquiring spacers in trans. In: Cell host \& microbe, 32, 2024, 875--886
2023Dmytrenko, Oleg and Neumann, Gina C and Hallmark, Thomson and Keiser, Dylan J and Crowley, Valerie M and Vialetto, Elena and Mougiakos, Ioannis and Wandera, Katharina G and Domgaard, Hannah and Weber, Johannes and others: Cas12a2 elicits abortive infection through RNA-triggered destruction of dsDNA. In: Nature, 613, 2023, 588--594
2022Vialetto, Elena and Yu, Yanying and Collins, Scott P and Wandera, Katharina G and Barquist, Lars and Beisel, Chase L: A target expression threshold dictates invader defense and prevents autoimmunity by CRISPR-Cas13. In: Cell host \& microbe, 30, 2022, 1151--1162
2022Wandera, Katharina G and Alkhnbashi, Omer S and vI Bassett, Harris and Mitrofanov, Alexander and Hauns, Sven and Migur, Anzhela and Backofen, Rolf and Beisel, Chase L: Anti-CRISPR prediction using deep learning reveals an inhibitor of Cas13b nucleases. In: Molecular cell, 82, 2022, 2714--2726
2021Wandera, Katharina G and Beisel, Chase L: Rapidly Characterizing CRISPR-Cas13 Nucleases Using Cell-Free Transcription-Translation Systems. Post-Transcriptional Gene Regulation. Springer US New York, NY, 2021. 135--153
2020Wandera, Katharina G and Collins, Scott P and Wimmer, Franziska and Marshall, Ryan and Noireaux, Vincent and Beisel, Chase L: An enhanced assay to characterize anti-CRISPR proteins using a cell-free transcription-translation system. In: Methods, 172, 2020, 42--50