Dr. Jan Vincent Arafiles

Profil

Derzeitige StellungPost Doc
FachgebietBioorganische und Biologische Chemie,Biochemie
KeywordsCorrelative super-resolution microscopy and electr, Bioconjugation, Intracellular delivery, Chemical biology, Bicyclic cell-penetrating peptide
Auszeichnungen

2015: Japanese Government (Monbukagakusho) Scholarship

Aktuelle Kontaktadresse

LandDeutschland
OrtBerlin
Universität/InstitutionLeibniz-Institut für Molekulare Pharmakologie (FMP)
Institut/AbteilungAbteilung Chemische Biologie

Gastgeber*innen während der Förderung

Prof. Dr. Christian HackenbergerAbteilung Chemische Biologie, Leibniz-Institut für Molekulare Pharmakologie (FMP), Berlin
Beginn der ersten Förderung01.10.2022

Programm(e)

2022Humboldt-Forschungsstipendien-Programm für Postdocs

Publikationen (Auswahl)

2023 Jan Vincent V. Arafiles, Jonathan Franke, Luise Franz, Jacobo Gómez-González, Kristin Kemnitz-Hassanin, and Christian P. R. Hackenberger: Cell-Surface-Retained Peptide Additives for the Cytosolic Delivery of Functional Proteins. In: Journal of the Americal Chemical Society, 145, 2023, 24535–24548
2020Hsu, Wei-Yuan, Masuda Toshihiro, Afonin Sergii, Sakai Takayuki, Arafiles Jan Vincent V., Kawano Kenichi, Hirose Hisaaki, Imanishi Miki, Ulrich Anne S. and Futaki Shiroh: Enhancing the activity of membrane remodeling epsin-peptide by trimerization. In: Bioorganic & Medicinal Chemistry Letters, 30, 2020, 127190
2020Futaki, Shiroh and Arafiles, Jan Vincent V. and Hirose, Hisaaki: {Peptide-assisted Intracellular Delivery of Biomacromolecules}. In: Chemistry Letters, 49, 2020, 1088--1094
2020Arafiles, Jan Vincent V. and Hirose, Hisaaki and Akishiba, Misao and Tsuji, Shogo and Imanishi, Miki and Futaki, Shiroh: {Stimulating Macropinocytosis for Intracellular Nucleic Acid and Protein Delivery: A Combined Strategy with Membrane-Lytic Peptides to Facilitate Endosomal Escape}. In: Bioconjugate Chemistry, 31, 2020, 547--553
n.n.Sakamoto, Kentarou and Furukawa, Hiroto and Arafiles, Jan Vincent and Imanishi, Miki and Matsuura, Kazunori and Futaki, Shiroh: {Artificial Nanocage Formed via Self-Assembly of $\beta$-Annulus Peptide for Delivering Biofunctional Proteins into Cell Interiors}. In: Bioconjugate Chemistry, 33, n.n., 311 -- 320
n.n.Nagano, Yuki and Arafiles, Jan Vincent and Kuwata, Keiko and Kawaguchi, Yoshimasa and Imanishi, Miki and Hirose, Hisaaki and Futaki, Shiroh: {Grafting Hydrophobic Amino Acids Critical for Inhibition of Protein–Protein Interactions on a Cell-Penetrating Peptide Scaffold}. In: Molecular Pharmaceutics, 0, n.n., null -- null
n.n.Nakagawa, Yuna and Arafiles, Jan Vincent and Kawaguchi, Yoshimasa and Nakase, Ikuhiko and Hirose, Hisaaki and Futaki, Shiroh: {Stearylated Macropinocytosis-Inducing Peptides Facilitating the Cellular Uptake of Small Extracellular Vesicles}. In: Bioconjugate Chemistry, 0, n.n., null -- null